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metaraminol and Endotoxin Shock

metaraminol has been researched along with Endotoxin Shock in 33 studies

Metaraminol: A sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. It has been used primarily as a vasoconstrictor in the treatment of HYPOTENSION.
metaraminol : A member of the class of phenylethanolamines that is 2-amino-1-phenylethanol substituted by a methyl group at position 2 and a phenolic hydroxy group at position 1. A sympathomimetic agent , it is used in the treatment of hypotension.

Research Excerpts

ExcerptRelevanceReference
" Indications for adrenergic stimulators include severe hypotensive episodes, in which case an alpha-beta stimulator such as metaraminol or norepinephrine is the therapy of choice; hemorrhagic shock, in which administration of an alpha-beta stimulator will help maintain essential cerebral and cardiac function by shunting blood to these areas while volume is being replaced; cardiogenic shock, in which vasodilators may reduce cardiac work by reducing diastolic blood pressure but coronary blood flow will also be reduced, counteracting the effects of decreasing the cardiac load; and endotoxic shock, in which the circulating blood volume decreases and venous return and cardiac output also decrease."3.65Vasopressor agents in shock. ( Mills, LC; Moyer, JH, 1975)
"Ten consecutive septic shock patients receiving norepinephrine to maintain the mean arterial pressure higher than 65 mmHg."2.71Norepinephrine and metaraminol in septic shock: a comparison of the hemodynamic effects. ( Bernardini, A; Natalini, G; Pletti, C; Rosano, A; Schivalocchi, V; Taranto, M, 2005)
"We hypothesised that in septic shock there is an impaired autoregulation of microcirculation, and blood flow is totally dependent on CDP."1.42Endotoxaemic myocardial dysfunction: the role of coronary driving pressure in subendocardial perfusion. ( Ariga, SK; Batista, TR; Lorigados, CB; Soriano, FG; Velasco, IT, 2015)
"Ninety-eight patients with septic shock were divided into three groups according to the highest infusing rate of metaraminol, with the lightest infusing rate of (0."1.34Effect of dopamine and metaraminol on the renal function of patients with septic shock. ( Chen, M; Chen, SY; Hou, LC; Hu, WN; Huo, TT; Li, SZ; Wang, Q; Wang, YL; Xiong, LZ; Zhang, XJ, 2007)
"Bacteremic shock is second in frequency only to myocardial infarction as a cause of hypotension and death in hospitalized medical patients."1.24BACTEREMIC SHOCK--A MEDICAL EMERGENCY. ( CAMERON, DG; DIRKS, JH; RUEDY, J, 1963)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199029 (87.88)18.7374
1990's0 (0.00)18.2507
2000's2 (6.06)29.6817
2010's1 (3.03)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Abu Sardaneh, A1
Goradia, S1
Narayan, SW1
Penm, J1
McLachlan, AJ1
Patanwala, AE1
Lorigados, CB1
Ariga, SK1
Batista, TR1
Velasco, IT1
Soriano, FG1
VICK, JA1
LAFAVE, J1
MACLEAN, LD1
RUEDY, J1
DIRKS, JH1
CAMERON, DG1
BOOKRAJIAN, EN1
LEFEVRE, H1
NIELSEN, B1
SPOEREL, WE1
SELENY, FL1
WILLIAMSON, RD1
SAMBHI, MP1
WEIL, MH3
UDHOJI, VN1
ROSOFF, L1
SMULYAN, H1
CUDDY, RP1
EICH, RH1
WATTS, FB1
MORRIS, JA1
SMITH, RW1
ASSALI, NS1
DAUGHERTY, RM1
ROBARDS, VL1
THOMPSON, IM1
LINDBERG, DA1
CONACHER, WD1
DOSHI, C1
JAMES, OB1
SHUBIN, H2
Natalini, G1
Schivalocchi, V1
Rosano, A1
Taranto, M1
Pletti, C1
Bernardini, A1
Hou, LC1
Li, SZ1
Xiong, LZ1
Chen, SY1
Chen, M1
Zhang, XJ1
Huo, TT1
Wang, Q1
Wang, YL1
Hu, WN1
Kardos, GG1
Bourry, J1
Sainty, JM1
Roux, JJ1
Ressiot, G1
Moyer, JH3
Mills, LC3
Cavanagh, D1
Dahm, CH1
Marshall, BR1
Hepler, JK1
Jinguji, MS1
Berger, RL1
Saini, VK1
Long, W1
Hechtman, H1
Hood, W1
Sugerman, HJ1
Diaco, JF1
Pollock, TW1
Miller, LD1
Martinez, JT1
Fernandez, G1
Vazquez-Leon, H1
Shoemaker, WC2
Brown, RS2
Torsti, P1
Blair, E1
Carey, JS1
Woodward, NW1
Mohr, PA1
Speroff, L1

Trials

2 trials available for metaraminol and Endotoxin Shock

ArticleYear
Norepinephrine and metaraminol in septic shock: a comparison of the hemodynamic effects.
    Intensive care medicine, 2005, Volume: 31, Issue:5

    Topics: Dose-Response Relationship, Drug; Hemodynamics; Humans; Metaraminol; Middle Aged; Norepinephrine; Ox

2005
Clinical evaluation of new therapeutic concepts in septic shock.
    Obstetrics and gynecology, 1966, Volume: 27, Issue:2

    Topics: Abortion, Septic; Clinical Trials as Topic; Female; Heparin; Humans; Metaraminol; Phenoxybenzamine;

1966

Other Studies

31 other studies available for metaraminol and Endotoxin Shock

ArticleYear
Dose equivalence between metaraminol and norepinephrine in critical care.
    British journal of clinical pharmacology, 2022, Volume: 88, Issue:1

    Topics: Adult; Aged; Critical Care; Critical Illness; Humans; Male; Metaraminol; Norepinephrine; Retrospecti

2022
Endotoxaemic myocardial dysfunction: the role of coronary driving pressure in subendocardial perfusion.
    Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2015, Volume: 17, Issue:1

    Topics: Animals; Coronary Circulation; Coronary Vessels; Endotoxemia; Heart; Hemodynamics; Male; Metaraminol

2015
RENAL FAILURE ASSOCIATED WITH ENDOTOXIN SHOCK.
    Minnesota medicine, 1963, Volume: 46

    Topics: Acute Kidney Injury; Animals; Dogs; Endotoxins; Escherichia coli; Hydrocortisone; Metaraminol; Minne

1963
BACTEREMIC SHOCK--A MEDICAL EMERGENCY.
    Canadian Medical Association journal, 1963, Nov-23, Volume: 89

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Emergencies; Humans; Hypotension; Metaraminol; M

1963
SEPTIC ABORTION WITH BACTEREMIC SHOCK.
    The Journal of the Medical Society of New Jersey, 1963, Volume: 60

    Topics: Abortion, Septic; Chloramphenicol; Female; Humans; Hydrocortisone; Metaraminol; Norepinephrine; Oxyg

1963
[SEPTIC SHOCK IN ABORTION].
    Ugeskrift for laeger, 1963, Dec-13, Volume: 125

    Topics: Abortion, Induced; Abortion, Septic; Abortion, Therapeutic; Anti-Bacterial Agents; Antibiotics, Anti

1963
SHOCK CAUSED BY CONTINUOUS INFUSION OF METARAMINOL BITARTRATE (ARAMINE).
    Canadian Medical Association journal, 1964, Feb-01, Volume: 90

    Topics: Asthma; Blood Pressure; Blood Pressure Determination; Bronchitis; Geriatrics; Hemorrhoids; Humans; H

1964
EFFECT OF PRESSOR AMINES ON CARDIAC OUTPUT IN PATIENTS WITH ACUTE HYPOTENSION.
    Circulation, 1964, Volume: 30

    Topics: Amines; Barbiturates; Blood Pressure; Cardiac Output; Chlorpromazine; Dehydration; Drug Therapy; Dye

1964
HEMODYNAMIC EFFECTS OF PRESSOR AGENTS IN SEPTIC AND MYOCARDIAL INFARCTION SHOCK.
    JAMA, 1964, Oct-19, Volume: 190

    Topics: Angiotensins; Biomedical Research; Blood Circulation; Capillary Resistance; Drug Therapy; Heart Func

1964
MYOCARDIAL INFARCTION, GRAM-NEGATIVE BACTEREMIA, PROLONGED SHOCK, AND LEUKEMOID REACTION.
    American heart journal, 1965, Volume: 69

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Bacteremia; Diagnosis; Drug Therapy; Enterobacter ae

1965
HEMODYNAMIC ACTION OF VASOPRESSOR AND VASODEPRESSOR AGENTS IN ENDOTOXIN SHOCK.
    American journal of obstetrics and gynecology, 1965, Feb-15, Volume: 91

    Topics: Angiotensins; Blood Circulation; Blood Pressure; Blood Pressure Determination; Cardiac Output; Dogs;

1965
STEROIDS AND BACTEREMIC SHOCK.
    The Journal of the Oklahoma State Medical Association, 1965, Volume: 58

    Topics: Drug Therapy; Humans; Hydrocortisone; Metaraminol; Norepinephrine; Sepsis; Shock, Septic; Steroids

1965
UROLOGIC ASPECTS OF BACTEREMIA AND SEPTICEMIC SHOCK.
    The Journal of urology, 1965, Volume: 93

    Topics: Adrenal Cortex Hormones; Angiotensins; Anti-Bacterial Agents; Bacteremia; Drug Therapy; Geriatrics;

1965
BACTERAEMIC SHOCK AS MEDICAL EMERGENCY.
    Lancet (London, England), 1965, Jul-10, Volume: 1, Issue:7402

    Topics: Ampicillin; Angina Pectoris; Anti-Bacterial Agents; Bacteriological Techniques; Diagnosis, Different

1965
THE MECHANISM OF SHOCK FOLLOWING SUICIDAL DOSES OF BARBITURATES, NARCOTICS AND TRANQUILIZER DRUGS, WITH OBSERVATIONS ON THE EFFECTS OF TREATMENT.
    The American journal of medicine, 1965, Volume: 38

    Topics: Barbiturates; Blood Pressure; Blood Vessels; Blood Volume; Cardiac Catheterization; Cardiac Output;

1965
Effect of dopamine and metaraminol on the renal function of patients with septic shock.
    Chinese medical journal, 2007, Apr-20, Volume: 120, Issue:8

    Topics: Adult; APACHE; beta 2-Microglobulin; Blood Pressure; Blood Urea Nitrogen; Dopamine; Female; Heart Ra

2007
Isoproterenol in the treatment of shock due to bacteremia with gram-negative pathogens.
    The New England journal of medicine, 1966, Apr-21, Volume: 274, Issue:16

    Topics: Anti-Bacterial Agents; Bacteremia; Cardiotonic Agents; Drug Therapy, Combination; Female; Gram-Negat

1966
[Acute pancreatitis in the course of meprobamate poisoning. Possible role of pressor amine therapy].
    La Nouvelle presse medicale, 1976, Sep-18, Volume: 5, Issue:30

    Topics: Acute Disease; Adult; Amylases; Ascitic Fluid; Female; Humans; Hypothermia; Male; Meprobamate; Metar

1976
Vasopressor agents in shock.
    The American journal of nursing, 1975, Volume: 75, Issue:4

    Topics: Brain; Cerebrovascular Circulation; Humans; Metaraminol; Morphine; Myocardial Infarction; Nalorphine

1975
Endotoxic shock.
    Obstetrics and gynecology annual, 1972, Volume: 1

    Topics: Abortion, Septic; Animals; Anti-Bacterial Agents; Bacterial Infections; Blood Coagulation; Catechola

1972
Fatal Streptococcus pyogenes septicemia associated with an intrauterine device.
    Obstetrics and gynecology, 1973, Volume: 41, Issue:1

    Topics: Adult; Cervix Uteri; Chloramphenicol; Dexamethasone; Endometritis; Endometrium; Female; Humans; Intr

1973
The use of diastolic augmentation with the intra-aortic balloon in human septic shock with associated coronary artery disease.
    Surgery, 1973, Volume: 74, Issue:4

    Topics: Aged; Assisted Circulation; Blood Pressure; Blood Urea Nitrogen; Carbon Dioxide; Cardiac Output; Cen

1973
Treatment of shock caused by bacterial infections.
    California medicine, 1973, Volume: 119, Issue:5

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bicarbonates; Glucocorticoids; Heparin; Human

1973
Vasopressors for treating shock.
    Postgraduate medicine, 1974, Volume: 56, Issue:2

    Topics: Bacteria; Chloramphenicol; Epinephrine; Humans; Isoproterenol; Metaraminol; Methoxamine; Morphine; M

1974
Physiologic management of septicemic shock in man.
    Surgical forum, 1971, Volume: 22

    Topics: Hemodynamics; Humans; Isoproterenol; Metaraminol; Middle Aged; Pulmonary Edema; Sepsis; Shock, Septi

1971
The dilemma of vasopressors and vasodilators in the therapy of shock.
    Surgery, gynecology & obstetrics, 1971, Volume: 132, Issue:1

    Topics: Blood Pressure; Cardiac Output; Central Venous Pressure; Chlorpromazine; Heart Rate; Hemodynamics; H

1971
[The use of sympathomimetics and sympatholytics in shock].
    Duodecim; laaketieteellinen aikakauskirja, 1971, Volume: 87, Issue:4

    Topics: Chlorpromazine; Dopamine; Humans; Isoproterenol; Metaraminol; Norepinephrine; Phenoxybenzamine; Phen

1971
Acid-base balance in bacteremic shock.
    Archives of internal medicine, 1971, Volume: 127, Issue:4

    Topics: Acid-Base Equilibrium; Acidosis; Alkalosis; Alkalosis, Respiratory; Bicarbonates; Blood Pressure; Bu

1971
Indications for adrenergic stimulators in shock.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:4

    Topics: Blood Pressure; Blood Volume; Cardiac Output; Carotid Arteries; Central Venous Pressure; Cerebrovasc

1971
Hemodynamic effects of sympathomimetic amines in clinical shock.
    Surgery, gynecology & obstetrics, 1966, Volume: 122, Issue:2

    Topics: Blood Circulation; Cardiac Output; Humans; Isoproterenol; Metaraminol; Norepinephrine; Shock, Hemorr

1966
Bacterial shock in obstetrics and gynecology; with emphasis on the surgical management of septic abortion.
    American journal of obstetrics and gynecology, 1966, May-01, Volume: 95, Issue:1

    Topics: Abortion, Septic; Adult; Anti-Bacterial Agents; Female; Humans; Hysterectomy; Metaraminol; Middle Ag

1966