metallothionein has been researched along with Rhabdomyosarcoma* in 1 studies
1 other study(ies) available for metallothionein and Rhabdomyosarcoma
| Article | Year |
|---|---|
Basal metallothionein in tumors: widespread presence of apoprotein.
A survey has been conducted of solid and ascites tumors from mice and solid tumors in rats for the presence of metallothionein or metallothionein-like protein. In most tumors, a positive identification was made on the basis of Sephadex G-75 and HPLC-DEAE chromatography followed by competitive radioimmunoassay for metallothionein. Apometallothionein was revealed in a number of tumors for the first time by comparing the Sephadex G-75 chromatographic profiles of Zn in native cytosol and Cd in cytosol incubated briefly with CdCl2 to saturate free binding sites on the protein before Sephadex G-75 chromatography. In two cases unsaturation of metallothionein was correlated with a lack of zinc in the ascites fluid which supplies the tumor with zinc. Topics: Animals; Apoproteins; Binding, Competitive; Cadmium; Chromatography, Gel; Chromatography, High Pressure Liquid; Humans; Male; Mammary Neoplasms, Experimental; Melanoma, Experimental; Metallothionein; Mice; Neoplasms, Experimental; Radioimmunoassay; Rats; Rhabdomyosarcoma; Sarcoma, Experimental; Splenic Neoplasms; Zinc | 1994 |