metallothionein and Leukemia--Monocytic--Acute

metallothionein has been researched along with Leukemia--Monocytic--Acute* in 1 studies

Other Studies

1 other study(ies) available for metallothionein and Leukemia--Monocytic--Acute

Article	Year
Fragile sites at 16q22 are not at the breakpoint of the chromosomal rearrangement in AMMoL. Science (New York, N.Y.), 1987, Apr-03, Volume: 236, Issue:4797 There is much speculation about fragile sites on human chromosomes predisposing to specific chromosome rearrangements seen in cancer. Acute myelomonocytic leukemia is characterized by neoplastic chromosome rearrangements involving band 16q22 in patients who carry the rare fragile site at 16q22. This specific leukemic breakpoint is within the metallothionein gene cluster, which is here shown to be proximal to the rare fragile site (FRA16B) and to a common fragile site (FRA16C) in this region. Hence neither of these fragile sites are at the breakpoint in this leukemic chromosomal rearrangement. Topics: Chromosome Fragile Sites; Chromosome Fragility; Chromosome Mapping; Chromosomes, Human, Pair 16; DNA, Neoplasm; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Metallothionein; Translocation, Genetic	1987

Article

Year

Fragile sites at 16q22 are not at the breakpoint of the chromosomal rearrangement in AMMoL.

Science (New York, N.Y.), 1987, Apr-03, Volume: 236, Issue:4797

There is much speculation about fragile sites on human chromosomes predisposing to specific chromosome rearrangements seen in cancer. Acute myelomonocytic leukemia is characterized by neoplastic chromosome rearrangements involving band 16q22 in patients who carry the rare fragile site at 16q22. This specific leukemic breakpoint is within the metallothionein gene cluster, which is here shown to be proximal to the rare fragile site (FRA16B) and to a common fragile site (FRA16C) in this region. Hence neither of these fragile sites are at the breakpoint in this leukemic chromosomal rearrangement.

Topics: Chromosome Fragile Sites; Chromosome Fragility; Chromosome Mapping; Chromosomes, Human, Pair 16; DNA, Neoplasm; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Metallothionein; Translocation, Genetic

1987