metallothionein has been researched along with Gout* in 1 studies
1 other study(ies) available for metallothionein and Gout
Article | Year |
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Increased Metallothionein-1 Associated with Gout Activity and Tophi.
Gout is a chronic self-limiting inflammatory arthritis. An increase in metallothionein-1 (MT-1) has been reported in rheumatoid arthritis and osteoarthritis, and it attenuates inflammation and the pathology of diseases. This study aims to detect MT-1 levels in patients with gout and to explore its correlation with disease activity, clinical indexes, and inflammatory cytokines.. The expression of MT-1 messenger RNAs (mRNAs) and protein levels in patients with gout were measured using real-time polymerase chain reaction and enzyme-linked immunosorbent assay. Correlations between MT-1 and clinical indexes or inflammatory mediators were analyzed using Spearman's correlation test.. Compared with healthy controls (HCs,. The higher levels of MT-1 were found in patients with gout, which were correlated with disease activity and gout related pro-inflammatory cytokines. Indicating MT-1 may serve as a new marker for predicting disease activity. Topics: C-Reactive Protein; Cytokines; Gout; Humans; Interleukin-6; Leukocytes, Mononuclear; Metallothionein | 2023 |