metallothionein and Acrodermatitis

metallothionein has been researched along with Acrodermatitis* in 3 studies

Reviews

3 review(s) available for metallothionein and Acrodermatitis

ArticleYear
The Functions of Metallothionein and ZIP and ZnT Transporters: An Overview and Perspective.
    International journal of molecular sciences, 2016, Mar-04, Volume: 17, Issue:3

    Around 3000 proteins are thought to bind zinc in vivo, which corresponds to ~10% of the human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component that functions in numerous physiological processes. It is more widely used as a structural element in proteins than any other transition metal ion, is a catalytic component of many enzymes, and acts as a cellular signaling mediator. Thus, it is expected that zinc metabolism and homeostasis have sophisticated regulation, and elucidating the underlying molecular basis of this is essential to understanding zinc functions in cellular physiology and pathogenesis. In recent decades, an increasing amount of evidence has uncovered critical roles of a number of proteins in zinc metabolism and homeostasis through influxing, chelating, sequestrating, coordinating, releasing, and effluxing zinc. Metallothioneins (MT) and Zrt- and Irt-like proteins (ZIP) and Zn transporters (ZnT) are the proteins primarily involved in these processes, and their malfunction has been implicated in a number of inherited diseases such as acrodermatitis enteropathica. The present review updates our current understanding of the biological functions of MTs and ZIP and ZnT transporters from several new perspectives.

    Topics: Acrodermatitis; Animals; Cation Transport Proteins; Epigenesis, Genetic; Gene Expression Regulation; Genetic Predisposition to Disease; Homeostasis; Humans; Metallothionein; Phylogeny; Polymorphism, Single Nucleotide; Repressor Proteins; Zinc

2016
Trace elements in development and disease.
    Current problems in pediatrics, 1986, Volume: 16, Issue:2

    Topics: Acrodermatitis; Cadmium; Chromium; Copper; Disease; Disease Models, Animal; Growth; Hemochromatosis; Hepatolenticular Degeneration; Humans; Iron; Magnesium; Male; Menkes Kinky Hair Syndrome; Metallothionein; Milk, Human; Nucleic Acids; Selenium; Testis; Trace Elements; Zinc

1986
Physiological ligands for copper and zinc.
    Annual review of nutrition, 1983, Volume: 3

    Topics: Absorption; Acrodermatitis; Animals; Biological Availability; Biological Transport, Active; Blood Proteins; Copper; Enzymes; Hepatolenticular Degeneration; Humans; Ligands; Menkes Kinky Hair Syndrome; Metallothionein; Zinc

1983