mesoridazine has been researched along with Dementia Praecox in 25 studies
Mesoridazine: A phenothiazine antipsychotic with effects similar to CHLORPROMAZINE.
mesoridazine : A phenothiazine substituted at position 2 (para to the S atom) by a methylsulfinyl group, and on the nitrogen by a 2-(1-methylpiperidin-2-yl)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The relationship of plasma and red blood cell (RBC) levels of thioridazine to clinical response in schizophrenia was evaluated in a fixed-dose study." | 7.67 | Plasma and red cell levels of thioridazine and clinical response in schizophrenia. ( Allen, P; Baumgartner, R; Johnson, R; Ravichandran, GK; Schoolar, JC; Shvartsburd, A; Smith, RC, 1984) |
| "The relationship of plasma and red blood cell (RBC) levels of thioridazine to clinical response in schizophrenia was evaluated in a fixed-dose study." | 3.67 | Plasma and red cell levels of thioridazine and clinical response in schizophrenia. ( Allen, P; Baumgartner, R; Johnson, R; Ravichandran, GK; Schoolar, JC; Shvartsburd, A; Smith, RC, 1984) |
| "Mesoridazine besylate (Serentil) was evaluated in an eight-week open-label trial in 12 male and 41 female patients with chronic schizophrenia who had ceased to progress beyond a certain level of functioning despite continued psychotropic medication not including Serentil." | 3.65 | An open study of mesoridazine (Serentil) in chronic schizophrenics. ( Aguilar, SJ, 1975) |
| " Concentrations of THD, mesoridazine, and sulforidazine were measured in plasma samples obtained from 10 male inpatients, aged 36 to 78 years, at three different time points: A, during habitual monotherapy with THD at 88 +/-54 mg/day; B, after addition of a low dosage of fluvoxamine (25 mg twice a day) for 1 week; and C, 2 weeks after fluvoxamine discontinuation." | 1.30 | Pharmacokinetic interaction of fluvoxamine and thioridazine in schizophrenic patients. ( Agundez, JA; Benítez, J; Berecz, R; Carrillo, JA; Duran, M; Herraiz, AG; Llerena, A; Ramos, SI, 1999) |
| "Mesoridazine was found to have earlier peak blood levels and lower fecal excretion." | 1.25 | Absorption and excretion of thioridazine and mesoridazine in man. ( Charalampous, KD; Estevez, V; Johnson, PC, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (88.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thanacoody, RH | 1 |
| Daly, AK | 1 |
| Reilly, JG | 1 |
| Ferrier, IN | 1 |
| Thomas, SH | 1 |
| Charalampous, KD | 1 |
| Johnson, PC | 1 |
| Estevez, V | 1 |
| White, K | 2 |
| Busk, J | 2 |
| Eaton, E | 1 |
| Gomez, G | 1 |
| Razani, J | 1 |
| Sloane, RB | 2 |
| Jeste, DV | 1 |
| Linnoila, M | 1 |
| Wagner, RL | 1 |
| Wyatt, RJ | 1 |
| Shvartsburd, A | 2 |
| Nwokeafor, V | 1 |
| Smith, RC | 2 |
| Baumgartner, R | 1 |
| Ravichandran, GK | 1 |
| Schoolar, JC | 1 |
| Allen, P | 1 |
| Johnson, R | 1 |
| Carrillo, JA | 1 |
| Ramos, SI | 1 |
| Herraiz, AG | 1 |
| Llerena, A | 1 |
| Agundez, JA | 1 |
| Berecz, R | 1 |
| Duran, M | 1 |
| Benítez, J | 1 |
| Dallaire, S | 1 |
| Eaton, EM | 1 |
| Maloney, MP | 1 |
| Whipple, K | 1 |
| Tecce, JJ | 1 |
| Gardos, G | 1 |
| Cole, JO | 1 |
| Bowers, PA | 1 |
| Gottschalk, LA | 3 |
| Dinovo, E | 1 |
| Bierner, R | 1 |
| Gottlieb, JI | 1 |
| Lustberg, T | 1 |
| Swett, C | 1 |
| Lingjaerde, O | 1 |
| Aguilar, SJ | 1 |
| Vital-Herne, J | 1 |
| Gerbino, L | 1 |
| Kay, SR | 1 |
| Katz, IR | 1 |
| Opler, LA | 1 |
| Rao, ML | 1 |
| Brown, WA | 1 |
| Wagner, R | 1 |
| Bankier, RG | 1 |
| Mathewson, FA | 1 |
| Jost, F | 1 |
| Zmorski, T | 1 |
| Pieschl, D | 1 |
| Hamid, TA | 1 |
| Wertz, WJ | 1 |
| Dillenkoffer, RL | 1 |
| Gallant, DM | 1 |
| Phillips, JH | 1 |
| Palestine, ML | 1 |
| Dinovo, EC | 1 |
| Noble, EP | 1 |
| Biener, R | 1 |
2 reviews available for mesoridazine and Dementia Praecox
| Article | Year |
|---|---|
The pharmacokinetics of some psychoactive drugs and relationships to clinical response.
Topics: Humans; Kinetics; Mental Disorders; Mesoridazine; Psychotropic Drugs; Research; Schizophrenia; Thior | 1985 |
[The cardiovascular effects of neuroleptics based on current knowledge].
Topics: Adolescent; Adult; Aged; Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Blood Pressure; Ca | 1973 |
9 trials available for mesoridazine and Dementia Praecox
| Article | Year |
|---|---|
Dysphoric response to neuroleptics as a predictor of treatment outcome with schizophrenics. A comparative study of haloperidol versus mesoridazine.
Topics: Adult; Antipsychotic Agents; Clinical Trials as Topic; Double-Blind Method; Emotions; Female; Halope | 1981 |
Red blood cell and plasma levels of thioridazine and mesoridazine in schizophrenic patients.
Topics: Adolescent; Adult; Aged; Aging; Chromatography, Gas; Dose-Response Relationship, Drug; Erythrocytes; | 1984 |
Hemispheric dysfunction in schizophrenia: assessment by visual perception tasks.
Topics: Acute Disease; Adult; Cerebral Cortex; Dominance, Cerebral; Double-Blind Method; Female; Haloperidol | 1979 |
Plasma levels of mesoridazine and its metabolites and clinical response in acute schizophrenia after a single intramuscular drug dose.
Topics: Acute Disease; Clinical Trials as Topic; Half-Life; Humans; Injections, Intramuscular; Kinetics; Mes | 1975 |
Mesoridazine and thioridazine: clinical effects and blood levels in refractory schizophrenics.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Female; Hospitalization; Huma | 1986 |
A clinical study of mesoridazine and chlorpromazine in relapsed schizophrenic patients.
Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Blood Cell Count; Blood Sedimentation; Blood Urea | 1972 |
[Mesoridazine (TPS 23 Sandoz) in acute psychotic states].
Topics: Acute Disease; Aggression; Clinical Trials as Topic; Depersonalization; Evaluation Studies as Topic; | 1973 |
Mesoridazine versus chlorpromazine in acute schizophrenia: a double-blind investigation.
Topics: Acute Disease; Adolescent; Adult; Aged; Attitude; Chlorpromazine; Clinical Trials as Topic; Evaluati | 1973 |
Electrocardiographic evaluation of mesoridazine (Serentil).
Topics: Adult; Cardiovascular System; Clinical Trials as Topic; Electrocardiography; Female; Humans; Male; M | 1972 |
14 other studies available for mesoridazine and Dementia Praecox
| Article | Year |
|---|---|
Factors affecting drug concentrations and QT interval during thioridazine therapy.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alleles; Antipsychotic Agents; Aryl Hydrocarbon Hydroxy | 2007 |
Absorption and excretion of thioridazine and mesoridazine in man.
Topics: Absorption; Antipsychotic Agents; Feces; Humans; Male; Mesoridazine; Schizophrenia; Thioridazine; Ti | 1974 |
Serum neuroleptic concentrations and tardive dyskinesia.
Topics: Aged; Antipsychotic Agents; Biotransformation; Dose-Response Relationship, Drug; Dyskinesia, Drug-In | 1982 |
Plasma and red cell levels of thioridazine and clinical response in schizophrenia.
Topics: Adult; Dose-Response Relationship, Drug; Erythrocytes; Humans; Mesoridazine; Plasma; Psychiatric Sta | 1984 |
Pharmacokinetic interaction of fluvoxamine and thioridazine in schizophrenic patients.
Topics: Adult; Aged; Antipsychotic Agents; Cytochrome P-450 CYP2D6; Drug Interactions; Fluvoxamine; Humans; | 1999 |
Thioridazine (Mellaril) and mesoridazine (Serentil): prolongation of the QTc interval.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Contraindications; Heart Conduction System; Humans; Long | 2001 |
A CNV typology of chronic schizophrenics and response to drug treatment.
Topics: Adult; Contingent Negative Variation; Electrophysiology; Female; Humans; Male; Mesoridazine; Middle | 1979 |
Phenothiazine-induced priapism: a case report.
Topics: Adult; Chlorpromazine; Depression; Humans; Male; Mesoridazine; Priapism; Schizophrenia | 1977 |
Drug-induced dystonia.
Topics: Adjustment Disorders; Adult; Basal Ganglia Diseases; Chlorpromazine; Chlorprothixene; Female; Fluphe | 1975 |
[Mesoridazine (Lidanor"Sandoz")--a new neuroleptic closely related to thioridazine].
Topics: Humans; Mesoridazine; Schizophrenia | 1975 |
An open study of mesoridazine (Serentil) in chronic schizophrenics.
Topics: Adult; Aged; Chronic Disease; Drug Administration Schedule; Drug Evaluation; Female; Humans; Male; M | 1975 |
Radioreceptor assay and high-performance liquid chromatography yield similar results for serum thioridazine and its major metabolites.
Topics: Adult; Antidepressive Agents; Chromatography, High Pressure Liquid; Humans; Mesoridazine; Phenothiaz | 1988 |
Comparative study of two antipsychotic drugs in a state hospital.
Topics: Adult; Alcoholism; Bipolar Disorder; Chlorpromazine; Depression; Evaluation Studies as Topic; Female | 1972 |
Isolation of a possible new metabolite of thioridazine and mesoridazine from human plasma.
Topics: Chromatography, Gas; Chromatography, Thin Layer; Fluorometry; Humans; Mesoridazine; Schizophrenia; T | 1974 |