mesna has been researched along with Thymus-Neoplasms* in 1 studies
1 other study(ies) available for mesna and Thymus-Neoplasms
| Article | Year |
|---|---|
The effect of sodium-2-mercaptoethane-sulphonate, N-acetylcysteine and cysteine on the uptake of cytosine arabinoside by normal and neoplastic thymus cells of mice.
The effect of some sulfhydryl compounds on the uptake of cytosine arabinoside (Ara-C) by normal and neoplastically transformed mouse thymus cells was studied. Sodium 2-mercaptoethanesulphonate (Mesna) was found to greatly inhibit (in 80%) the uptake of Ara-C by normal cells. Two other SH-compounds (cysteine and N-acetyl-cysteine) displayed no such effect. None of the three compounds reduced the uptake of Ara-C by neoplastic thymus cells. The possible pharmacological implications of these findings are discussed. Topics: Acetylcysteine; Animals; Cells, Cultured; Cysteine; Cytarabine; Female; Male; Mercaptoethanol; Mesna; Mice; Thymus Gland; Thymus Neoplasms; Tumor Cells, Cultured | 1988 |