mesna and Bronchial-Neoplasms

mesna has been researched along with Bronchial-Neoplasms* in 2 studies

Other Studies

2 other study(ies) available for mesna and Bronchial-Neoplasms

ArticleYear
Difference in bioactivity between two preparations of cyclophosphamide.
    Lancet (London, England), 1983, Mar-26, Volume: 1, Issue:8326 Pt 1

    Topics: Animals; Bronchial Neoplasms; Cyclophosphamide; Humans; Mass Spectrometry; Mercaptoethanol; Mesna; Rats

1983
[Prevention of urinary tract toxicity of oxazaphosphorines by a "uroprotector". Report on a field study (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1979, Jun-01, Volume: 121, Issue:22

    In an open multicenter phase III trial, prophylaxis of the urinary tract with sodium 2-mercaptoethanesulfonate (Mesnum) was carried out in 242 patients treated with oxazaphosphorines for various malignant tumors. Under the protection of Mesnum 29 patients were treated with cyclophosphamide (Endoxan), 195 with ifosfamide (Holoxan) and 8 with trofosfamide (Ixoten). Other cytostatics were also used (polychemotherapy) in 92 cases. On administration of Mesnum, 7 macrohematurias reappeared, only 3 of them however with correct application, and 22 microhematurias, 12 of them with correct application. Cylindrurias were re-established in 3 patients. In Mesnum we have a compound which can control the urotoxicity ("uroprotector") of oxazaphosphorines which limits their therapeutic use.

    Topics: Adolescent; Adult; Aged; Bronchial Neoplasms; Child; Cyclophosphamide; Female; Gastrointestinal Diseases; Hematuria; Humans; Ifosfamide; Male; Mercaptoethanol; Mesna; Middle Aged; Ovarian Neoplasms; Phosphoramide Mustards; Testicular Neoplasms

1979