mesalamine has been researched along with Ulcer in 20 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Mesalazine suppository was given to her for about 4 months, and glutamine capsules for 2 months, but the rectal ulcer remained unhealed." | 4.12 | Platelet-rich plasma for the treatment of chronic rectal ulcer: A case report. ( Ge, D; Li, P; Li, Y; Liu, G; Liu, J; Liu, Z; Wang, H; Wang, L; Zhao, G, 2022) |
| " The prodrugs exhibited comparable ameliorating effect as that of sulfasalazine on trinitrobenzenesulfonic acid-induced experimental colitis in rats with a better safety profile." | 3.75 | Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease. ( Bhatt, L; Dhaneshwar, SS; Gairola, N; Kadam, SS; Kandpal, M; Rathi, B; Vadnerkar, G, 2009) |
| "Endoscopic postoperative recurrences occur early after 'curative' surgery for Crohn's disease." | 2.68 | Placebo-controlled clinical trial of mesalazine in the prevention of early endoscopic recurrences after resection for Crohn's disease. Groupe d'Etudes Thérapeutiques des Affections Inflammatoires Digestives (GETAID). ( Belaiche, J; Cortot, A; Daurat, M; Dupas, JL; Faucheron, JL; Florent, C; Gendre, JP; Jacquet, N; Lerebours, E; Malafosse, M; Michot, F; Modigliani, R; Quandale, P; Rothman, N; Sahmound, T; Sarfaty, E; Soulé, JC; Valleur, P, 1996) |
| "Thirty-eight patients with distal ulcerative colitis (n = 17) or ulcerative proctitis (n = 21) in clinical, endoscopic, and histologic remission were randomly assigned to receive either oral mesalazine (0." | 2.67 | Intermittent therapy with high-dose 5-aminosalicylic acid enemas maintains remission in ulcerative proctitis and proctosigmoiditis. ( Hatzis, A; Mantzaris, GJ; Petraki, K; Spiliadi, C; Triantaphyllou, G, 1994) |
| "Distal ulcerative colitis (UC) is responsible for distressing symptoms and reduces quality of life (QoL)." | 1.72 | Real-world evidence of quality of life improvement in patients with distal ulcerative colitis treated by mesalazine: the Quartz study. ( Caron, B; Gonzalez, F; Paupard, T; Peyrin-Biroulet, L; Siproudhis, L, 2022) |
| "Furthermore, the ulcer has since maintained the scar stage despite successfully weaning the patient from PSL." | 1.48 | Effects of the Concomitant Use of Low-dose Clarithromycin with an Anti-TNFα Antibody in a Patient with Intestinal Behçet Disease. ( Hirayama, T; Honda, A; Ikegami, T; Iwamoto, J; Konishi, N; Matsuzaki, Y; Monma, T; Murakami, M; Ueda, H; Yara, S, 2018) |
| "This syndrome is diagnosed based on clinical symptoms and endoscopic and histological findings, but SRUS often goes unrecognized or is easily confused with other diseases such as inflammatory bowel disease, amoebiasis, malignancy, and other causes of rectal bleeding such as a juvenile polyps." | 1.39 | Solitary rectal ulcer syndrome in children: a report of six cases. ( Eken, KG; Kalyoncu, D; Urgancı, N, 2013) |
| "During the follow-up period, cumulative recurrence rates for intestinal BD were 24." | 1.36 | Response rates to medical treatments and long-term clinical outcomes of nonsurgical patients with intestinal Behçet disease. ( Cheon, JH; Chung, MJ; Kim, NK; Kim, SU; Kim, TI; Kim, WH; Park, JJ, 2010) |
| "Intestinal Behcet's disease in a 19-year-old girl was diagnosed because of the history of recurrent oral aphthous ulcers and typical endoscopic findings of esophageal and ileal ulcers." | 1.31 | The beneficial effect of mesalazine on esophageal ulcers in intestinal Behcet's disease. ( Araki, Y; Chijiiwa, Y; Harada, N; Koubokawa, M; Nawata, H; Ochiai, T; Sonta, T; Tamura, Y, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 10 (50.00) | 24.3611 |
| 2020's | 3 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhaneshwar, SS | 2 |
| Chail, M | 1 |
| Patil, M | 1 |
| Naqvi, S | 1 |
| Vadnerkar, G | 2 |
| Gairola, N | 1 |
| Kandpal, M | 1 |
| Bhatt, L | 1 |
| Rathi, B | 1 |
| Kadam, SS | 1 |
| Paupard, T | 1 |
| Gonzalez, F | 1 |
| Caron, B | 1 |
| Siproudhis, L | 1 |
| Peyrin-Biroulet, L | 1 |
| Liu, G | 1 |
| Li, Y | 2 |
| Wang, L | 1 |
| Li, P | 1 |
| Liu, Z | 1 |
| Liu, J | 1 |
| Ge, D | 1 |
| Zhao, G | 1 |
| Wang, H | 1 |
| Ahmad, H | 1 |
| Verma, S | 1 |
| Kumar, VL | 1 |
| Iwamoto, J | 1 |
| Murakami, M | 1 |
| Konishi, N | 1 |
| Monma, T | 1 |
| Ueda, H | 1 |
| Yara, S | 1 |
| Hirayama, T | 1 |
| Ikegami, T | 1 |
| Honda, A | 1 |
| Matsuzaki, Y | 1 |
| Awaji, K | 1 |
| Inokuchi, R | 1 |
| Maehara, H | 1 |
| Moriyama, M | 1 |
| Ohmae, T | 1 |
| Okamoto, M | 1 |
| Suyama, Y | 1 |
| Tominaga, K | 1 |
| Kamimura, K | 1 |
| Takahashi, K | 1 |
| Yokoyama, J | 1 |
| Terai, S | 1 |
| Sato, S | 1 |
| Yashiro, M | 1 |
| Matsuoka, N | 1 |
| Kawana, S | 1 |
| Asano, T | 1 |
| Kobayashi, H | 1 |
| Tasaki, K | 1 |
| Watanabe, H | 1 |
| Hashimoto, Y | 1 |
| Migita, K | 1 |
| Newton, AMJ | 1 |
| Lakshmanan, P | 1 |
| Urgancı, N | 1 |
| Kalyoncu, D | 1 |
| Eken, KG | 1 |
| Nishizaki, Y | 1 |
| Yamagami, S | 1 |
| Hayakawa, D | 1 |
| Takashima, S | 1 |
| Nomura, O | 1 |
| Sai, E | 1 |
| Kon, K | 1 |
| Matsuyama, S | 1 |
| Watanabe, S | 1 |
| Daida, H | 1 |
| Bain, JA | 1 |
| Chung, MJ | 1 |
| Cheon, JH | 1 |
| Kim, SU | 1 |
| Park, JJ | 1 |
| Kim, TI | 1 |
| Kim, NK | 1 |
| Kim, WH | 1 |
| Perito, ER | 1 |
| Mileti, E | 1 |
| Dalal, DH | 1 |
| Cho, SJ | 1 |
| Ferrell, LD | 1 |
| McCracken, M | 1 |
| Heyman, MB | 1 |
| Ono, M | 1 |
| Murakami, K | 1 |
| Oda, M | 1 |
| Miyajima, H | 1 |
| Watanabe, K | 1 |
| Sato, R | 1 |
| Nasu, M | 1 |
| Kashima, K | 1 |
| Mantzaris, GJ | 1 |
| Hatzis, A | 1 |
| Petraki, K | 1 |
| Spiliadi, C | 1 |
| Triantaphyllou, G | 1 |
| Florent, C | 1 |
| Cortot, A | 1 |
| Quandale, P | 1 |
| Sahmound, T | 1 |
| Modigliani, R | 1 |
| Sarfaty, E | 1 |
| Valleur, P | 1 |
| Dupas, JL | 1 |
| Daurat, M | 1 |
| Faucheron, JL | 1 |
| Lerebours, E | 1 |
| Michot, F | 1 |
| Belaiche, J | 1 |
| Jacquet, N | 1 |
| Soulé, JC | 1 |
| Rothman, N | 1 |
| Gendre, JP | 1 |
| Malafosse, M | 1 |
| Sonta, T | 1 |
| Araki, Y | 1 |
| Koubokawa, M | 1 |
| Tamura, Y | 1 |
| Ochiai, T | 1 |
| Harada, N | 1 |
| Chijiiwa, Y | 1 |
| Nawata, H | 1 |
| Kosaka, T | 1 |
| Tanaka, J | 1 |
| Tomita, T | 1 |
| Matsumura, T | 1 |
| Ohnishi, K | 1 |
| Fukuda, Y | 1 |
| Tamura, K | 1 |
| Shimoyama, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| QUality of Life in pAtients With Mild to modeRate Active procTitis Treated by mesalaZine (Pentasa®)[NCT02368743] | 117 participants (Actual) | Observational | 2015-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mesalamine and Ulcer
| Article | Year |
|---|---|
[A case of simple ulcer with ulcerative colitis].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Behcet Syndrome; Cecal Diseases; Colit | 2005 |
2 trials available for mesalamine and Ulcer
| Article | Year |
|---|---|
Intermittent therapy with high-dose 5-aminosalicylic acid enemas maintains remission in ulcerative proctitis and proctosigmoiditis.
Topics: Administration, Oral; Administration, Rectal; Adolescent; Adult; Aged; Aminosalicylic Acids; Colitis | 1994 |
Placebo-controlled clinical trial of mesalazine in the prevention of early endoscopic recurrences after resection for Crohn's disease. Groupe d'Etudes Thérapeutiques des Affections Inflammatoires Digestives (GETAID).
Topics: Administration, Oral; Adolescent; Adult; Aged; Aminosalicylic Acids; Anastomosis, Surgical; Anti-Inf | 1996 |
17 other studies available for mesalamine and Ulcer
| Article | Year |
|---|---|
Colon-specific mutual amide prodrugs of 4-aminosalicylic acid for their mitigating effect on experimental colitis in rats.
Topics: Aminosalicylic Acids; Animals; Colitis; Colon; Drug Delivery Systems; Drug Stability; Drug-Related S | 2009 |
Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease.
Topics: Aminosalicylic Acids; Animals; Arthritis; Colitis; Colon; Female; Inflammatory Bowel Diseases; Male; | 2009 |
Real-world evidence of quality of life improvement in patients with distal ulcerative colitis treated by mesalazine: the Quartz study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Humans; Inflammatory Bowel Diseases; M | 2022 |
Platelet-rich plasma for the treatment of chronic rectal ulcer: A case report.
Topics: Capsules; Colonic Diseases; Female; Glutamine; Humans; Mesalamine; Platelet-Rich Plasma; Rectal Dise | 2022 |
Effect of roxithromycin on mucosal damage, oxidative stress and pro-inflammatory markers in experimental model of colitis.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Diclofenac; Edema; | 2018 |
Effects of the Concomitant Use of Low-dose Clarithromycin with an Anti-TNFα Antibody in a Patient with Intestinal Behçet Disease.
Topics: Adalimumab; Aged; Anti-Inflammatory Agents; Behcet Syndrome; Cecal Diseases; Clarithromycin; Drug Th | 2018 |
Gastrointestinal Behçet's disease: periodic fever, multiple ulcers and trisomy 8 in elderly man.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; Capsule Endoscopy; Chromosomes, Huma | 2018 |
A case of Behçet's disease with various gastrointestinal findings.
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; Colitis, U | 2018 |
Behçet disease associated with gastrointestinal amyloidosis manifested as hematochezia: A case report.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; Colchicine; Colon; Colonic Diseases; Gastr | 2018 |
Comparative Efficacy of Chitosan, Pectin Based Mesalamine Colon Targeted Drug Delivery Systems on TNBS-induced IBD Model Rats.
Topics: Animals; Anti-Inflammatory Agents; Chitosan; Colon; Disease Models, Animal; Drug Delivery Systems; H | 2020 |
Solitary rectal ulcer syndrome in children: a report of six cases.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Child; Colonoscopy; Female; | 2013 |
Esophageal ulcer of unknown origin complicated by left atrial myxoma.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Esophageal Diseases; Female; Heart Atria; Heart Neop | 2015 |
Mesalamine-induced fever: an important reminder to prescribers.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Fever; Humans; Male; Mesalamine; Middle A | 2015 |
Response rates to medical treatments and long-term clinical outcomes of nonsurgical patients with intestinal Behçet disease.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Azathiopr | 2010 |
Solitary rectal ulcer syndrome in children and adolescents.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Child; Female; Follow-Up Studies; Humans; Infla | 2012 |
The beneficial effect of mesalazine on esophageal ulcers in intestinal Behcet's disease.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Behcet Syndrome; Esophagea | 2000 |
[A case of successful mesalazine enema for rectal cavitating ulcer of Crohn's disease].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Enema; Female; Humans; Mesalamine; Re | 2001 |