Page last updated: 2024-10-30

mesalamine and Sterility, Male

mesalamine has been researched along with Sterility, Male in 13 studies

Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.

Research Excerpts

ExcerptRelevanceReference
"The prevalence rate of Crohn's disease and ulcerative colitis in our male infertile patients was 163 per 100,000 men and 490 per 100,000 men, respectively."1.40Inflammatory bowel disease in subfertile men and the effect of mesalazine on fertility. ( Arai, G; Iwahata, T; Kobori, Y; Okada, H; Shin, T; Soh, S; Suzuki, K; Yagi, H, 2014)
"Use of sulphasalazine in ulcerative colitis patients is hampered by a variety of side-effects, including male infertility."1.31Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects. ( Crispino, P; Di Paolo, MC; Iacopini, F; Paoluzi, OA; Paoluzi, P; Pica, R; Rivera, M; Spera, G, 2001)
"A male patient suffering from ulcerative colitis, presented with primary infertility due to sulphasalazine therapy."1.28Sulphasalazine-induced reversible male infertility. ( Delaere, KP; Meuleman, EJ; Strijbos, WE, 1989)
"Sixteen patients with quiescent ulcerative colitis were studied."1.27Sulphasalazine induced seminal abnormalities in ulcerative colitis: results of mesalazine substitution. ( Goodman, MJ; Lecarpentier, J; Mandal, BK; Mani, V; Riley, SA; Turnberg, LA, 1987)
"We report the case of a man with ulcerative colitis in whom infertility and a markedly abnormal SPA were demonstrated while he was taking sulfasalazine."1.27Sulfasalazine-induced abnormal sperm penetration assay reversed on changing to 5-aminosalicylic acid enemas. ( Batzer, FR; Chatzinoff, M; Corson, SL; Friedman, LS; Guarino, JM, 1988)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19909 (69.23)18.7374
1990's0 (0.00)18.2507
2000's3 (23.08)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shin, T1
Kobori, Y1
Suzuki, K1
Iwahata, T1
Yagi, H1
Soh, S1
Arai, G1
Okada, H1
Saha, S1
Esposti, SD1
Chermesh, I1
Eliakim, R1
McIntyre, PB1
Lennard-Jones, JE1
Cann, PA1
Holdsworth, CD1
Shaffer, JL1
Kershaw, A1
Berrisford, MH1
Di Paolo, MC1
Paoluzi, OA1
Pica, R1
Iacopini, F1
Crispino, P1
Rivera, M1
Spera, G1
Paoluzi, P1
Friedman, LS2
Delaere, KP1
Strijbos, WE1
Meuleman, EJ1
Wu, FC1
Aitken, RJ1
Ferguson, A1
Riley, SA2
Lecarpentier, J1
Mani, V1
Goodman, MJ1
Mandal, BK1
Turnberg, LA1
Chatzinoff, M1
Guarino, JM1
Corson, SL1
Batzer, FR1

Reviews

1 review available for mesalamine and Sterility, Male

ArticleYear
Reproductive issues in inflammatory bowel disease.
    Medicine and health, Rhode Island, 2009, Volume: 92, Issue:4

    Topics: Adaptation, Psychological; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathio

2009

Other Studies

12 other studies available for mesalamine and Sterility, Male

ArticleYear
Inflammatory bowel disease in subfertile men and the effect of mesalazine on fertility.
    Systems biology in reproductive medicine, 2014, Volume: 60, Issue:6

    Topics: Anti-Inflammatory Agents; Colitis, Ulcerative; Crohn Disease; Female; Fertility; Gastrointestinal Ag

2014
Mesalazine-induced reversible infertility in a young male.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:8

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Humans; Infertility, Male; Male; Mesalamine; Proctoc

2004
Reversal with balsalazide of infertility caused by sulphsalazine.
    British medical journal (Clinical research ed.), 1984, Jun-02, Volume: 288, Issue:6431

    Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Humans; Infertility, Male; Male; Mesalamine; Pheny

1984
Reversal of male infertility on changing treatment from sulphasalazine to 5-aminosalicylic acid.
    Lancet (London, England), 1984, May-19, Volume: 1, Issue:8386

    Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Humans; Infertility, Male; Male; Mesalamine; Sulfa

1984
Sulphasalazine-induced infertility reversed on transfer to 5-aminosalicylic acid.
    Lancet (London, England), 1984, Jun-02, Volume: 1, Issue:8388

    Topics: Adult; Aminosalicylic Acids; Delayed-Action Preparations; Humans; Infertility, Male; Male; Mesalamin

1984
Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2001, Volume: 33, Issue:7

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Desensitization, Im

2001
Male infertility related to 5-ASA enemas.
    Digestive diseases and sciences, 1989, Volume: 34, Issue:5

    Topics: Aminosalicylic Acids; Colitis, Ulcerative; Enema; Humans; Infertility, Male; Male; Mesalamine; Sulfa

1989
Sulphasalazine-induced reversible male infertility.
    Acta urologica Belgica, 1989, Volume: 57, Issue:1

    Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Follicle Stimulating Hormone; Humans; Infertility,

1989
Inflammatory bowel disease and male infertility: effects of sulfasalazine and 5-aminosalicylic acid on sperm-fertilizing capacity and reactive oxygen species generation.
    Fertility and sterility, 1989, Volume: 52, Issue:5

    Topics: Adult; Aminosalicylic Acids; Animals; Cricetinae; Female; Free Radicals; Humans; Infertility, Male;

1989
Sulphasalazine induced seminal abnormalities in ulcerative colitis: results of mesalazine substitution.
    Gut, 1987, Volume: 28, Issue:8

    Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Humans; Infertility, Male; Male; Mesalamine; Oligo

1987
Sulfasalazine-induced abnormal sperm penetration assay reversed on changing to 5-aminosalicylic acid enemas.
    Digestive diseases and sciences, 1988, Volume: 33, Issue:1

    Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Enema; Female; Humans; Infant, Newborn; Infertilit

1988
Sulfasalazine-induced abnormal sperm penetration.
    Digestive diseases and sciences, 1988, Volume: 33, Issue:11

    Topics: Aminosalicylic Acids; Female; Humans; Infertility, Male; Male; Mesalamine; Sperm-Ovum Interactions;

1988