mesalamine has been researched along with Renal Insufficiency in 10 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The package inserts for products containing 5-aminosalicylic acid, or mesalamine, include the following language regarding the risk of adverse kidney effects: "renal impairment, including minimal change nephropathy, acute and chronic interstitial nephritis, and rarely renal failure, has been reported in patients given products such as mesalamine delayed-release tablets that contain mesalamine or are converted to mesalamine." | 5.05 | The Association of Mesalamine With Kidney Disease. ( Adiga, A; Goldfarb, DS, 2020) |
| "A total of 103 patients (93." | 1.62 | Knowledge of 5-aminosalicylic acid nephrotoxicity and adherence to kidney function monitoring of patients with inflammatory bowel disease. ( Achit, H; Ayav, C; D'Amico, F; Danese, S; Frimat, L; Guillemin, F; Guillo, L; Peyrin-Biroulet, L; Weislinger, L, 2021) |
| " The aim of this study was to investigate the effect of long-term use of 5-ASA on renal function in patients with Crohn's disease (CD)." | 1.33 | 5-Aminosalicylates and effects on renal function in patients with Crohn's disease. ( de Jong, DJ; Habraken, CM; Naber, AH; Tielen, J; Wetzels, JF, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Menon, S | 1 |
| Bressler, B | 1 |
| Adiga, A | 1 |
| Goldfarb, DS | 1 |
| Weislinger, L | 1 |
| Guillo, L | 1 |
| D'Amico, F | 1 |
| Danese, S | 1 |
| Achit, H | 1 |
| Ayav, C | 1 |
| Guillemin, F | 1 |
| Peyrin-Biroulet, L | 1 |
| Frimat, L | 1 |
| Druez, A | 1 |
| Rahier, JF | 1 |
| Hébuterne, X | 1 |
| Akbal, E | 1 |
| Köklü, S | 1 |
| Koçak, E | 1 |
| Cakal, B | 1 |
| Kılıç, F | 1 |
| Masuda, H | 1 |
| Takahashi, Y | 1 |
| Nishida, Y | 1 |
| Asai, S | 1 |
| Elseviers, MM | 1 |
| D'Haens, G | 1 |
| Lerebours, E | 1 |
| Plane, C | 1 |
| Stolear, JC | 1 |
| Riegler, G | 1 |
| Capasso, G | 1 |
| Van Outryve, M | 1 |
| Mishevska-Mukaetova, P | 1 |
| Djuranovic, S | 1 |
| Pelckmans, P | 1 |
| De Broe, ME | 1 |
| de Jong, DJ | 1 |
| Tielen, J | 1 |
| Habraken, CM | 1 |
| Wetzels, JF | 1 |
| Naber, AH | 1 |
| Marteau, P | 1 |
| Devaux, CB | 1 |
| Musil, D | 1 |
1 review available for mesalamine and Renal Insufficiency
| Article | Year |
|---|---|
The Association of Mesalamine With Kidney Disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Monitoring; Humans; Inflammatory Bowel Diseases; Mesal | 2020 |
9 other studies available for mesalamine and Renal Insufficiency
| Article | Year |
|---|---|
Editorial: aminosalicylates and nephrotoxicity-an issue put to rest.
Topics: Case-Control Studies; Cohort Studies; Colitis, Ulcerative; Humans; Mesalamine; Renal Insufficiency | 2019 |
Knowledge of 5-aminosalicylic acid nephrotoxicity and adherence to kidney function monitoring of patients with inflammatory bowel disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Humans; Inflammatory Bowel Diseases; K | 2021 |
Methaemoglobinaemia and renal failure following mesalazine for treatment of inflammatory bowel disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Inflammatory Bowel Diseases; Mesalamine; Me | 2014 |
5-aminosalicylic acid induced multisystem disorders in the course of Crohn' s disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Female; Humans; Liver; Mesalamine; Pa | 2010 |
Comparison of the effect of mesalazine and sulfasalazine on laboratory parameters: a retrospective observational study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cohort Studi | 2012 |
Renal impairment in patients with inflammatory bowel disease: association with aminosalicylate therapy?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcera | 2004 |
5-Aminosalicylates and effects on renal function in patients with Crohn's disease.
Topics: Adult; Aging; Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Crohn Disease; Female; Health Sur | 2005 |
Mesalazine during pregnancy.
Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Infant, Newb | 1994 |
[Early renal failure caused by mesalazine].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Humans; Male; Mesalamine; Renal | 2000 |