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mesalamine and Proteinuria

mesalamine has been researched along with Proteinuria in 11 studies

Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"A randomized, 2-way, crossover study was conducted in 30 volunteers to compare the pharmacokinetic profile of a new once-daily dosing regimen of mesalazine (1 x 4 g/d) with the current twice-daily dosage (2 x 2 g/d) used in many European countries."2.73Is once-daily mesalazine equivalent to the currently used twice-daily regimen? A study performed in 30 healthy volunteers. ( Gandia, P; Houin, G; Idier, I, 2007)
"Patients with ulcerative colitis have a higher rate of tubular nephropathies."2.72[Characterization of proteinuria in patients with ulcerative colitis and therapy with aminosalicylates]. ( Aymaz, S; Buschhausen, L; Krakamp, B; Kruis, W; Weber, M, 2006)
"Tubular proteinuria is an extra-intestinal manifestation of inflammatory bowel disease irrespective of 5-ASA treatment."2.70Renal tubular injury is present in acute inflammatory bowel disease prior to the introduction of drug therapy. ( Fraser, JS; Lamb, EJ; Muller, AF; Newman, DJ; Smith, DJ, 2001)
"In an uncontrolled trial, patients with IgA nephropathy (IgAN) were treated with drugs that can alter the intestinal mucosal permeability to food antigens."2.67Low doses of drugs able to alter intestinal mucosal permeability to food antigens (5-aminosalicylic acid and sodium cromoglycate) do not reduce proteinuria in patients with IgA nephropathy: a preliminary noncontrolled trial. ( Arrigo, G; Bazzi, C; D'Amico, G; Petrini, C; Ragni, A; Rizza, V; Sinico, RA; Torpia, R, 1992)
"At least 1% of patients with Crohn's disease develop amyloidosis."2.45Crohn's disease and secondary amyloidosis: early complication? A case report and review of the literature. ( Basturk, T; Kusaslan, R; Ozagari, A; Ozturk, T; Unsal, A, 2009)
"The renal biopsy was performed and IgA nephropathy (type IV) was diagnosed."1.35[Crohn's disease in association with IgA nephropathy]. ( Choi, YJ; Chung, WC; Kim, HW; Lee, JM; Lee, JR; Lee, KM; Paik, CN; Yang, JM, 2008)
"Microproteinuria is mainly associated with UC and its activity but not affected by 5-ASA."1.33Microproteinuria in patients with inflammatory bowel disease: is it associated with the disease activity or the treatment with 5-aminosalicylic acid? ( Archimandritis, A; Dandakis, DC; Georgouli, A; Goumas, KE; Panagiotaki, M; Poulou, AC; Soutos, DC; Tyrmpas, I, 2006)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's7 (63.64)29.6817
2010's1 (9.09)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Guillo, L1
D'Amico, F1
Achit, H1
Ayav, C1
Guillemin, F1
Danese, S1
Frimat, L1
Peyrin-Biroulet, L1
Lee, JM1
Lee, KM1
Kim, HW1
Chung, WC1
Paik, CN1
Lee, JR1
Choi, YJ1
Yang, JM1
Basturk, T1
Ozagari, A1
Ozturk, T1
Kusaslan, R1
Unsal, A1
Velciov, S1
Gluhovschi, G1
Sporea, I1
Trandafirescu, V1
Petrica, L1
Bozdog, G1
Gluhovschi, C1
Bob, F1
Gădălean, F1
Buzaş, R1
Bobu, M1
Voicu, L1
Poulou, AC1
Goumas, KE1
Dandakis, DC1
Tyrmpas, I1
Panagiotaki, M1
Georgouli, A1
Soutos, DC1
Archimandritis, A1
Buschhausen, L1
Kruis, W2
Aymaz, S1
Weber, M1
Krakamp, B1
Gandia, P1
Idier, I1
Houin, G1
Schreiber, S1
Hämling, J1
Zehnter, E1
Howaldt, S1
Daerr, W1
Raedler, A1
Russo, GE1
Bauco, B1
Bosco, M1
Bonello, M1
Bisciglia, MF1
De Paola, A1
Villatico Campbell, S1
Fava, D1
Vitaliano, E1
Fraser, JS1
Muller, AF1
Smith, DJ1
Newman, DJ1
Lamb, EJ1
Bazzi, C1
Sinico, RA1
Petrini, C1
Rizza, V1
Torpia, R1
Arrigo, G1
Ragni, A1
D'Amico, G1

Reviews

2 reviews available for mesalamine and Proteinuria

ArticleYear
Kidney function monitoring to prevent 5-aminosalicylic acid nephrotoxicity: What the gastroenterologist should know.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2021, Volume: 53, Issue:6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Creatinine; Glomerular Filtration Rate

2021
Crohn's disease and secondary amyloidosis: early complication? A case report and review of the literature.
    Journal of renal care, 2009, Volume: 35, Issue:3

    Topics: Adult; Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Colchicine; Crohn Disease; Dise

2009

Trials

4 trials available for mesalamine and Proteinuria

ArticleYear
[Characterization of proteinuria in patients with ulcerative colitis and therapy with aminosalicylates].
    Medizinische Klinik (Munich, Germany : 1983), 2006, Oct-15, Volume: 101, Issue:10

    Topics: Acute Disease; Adolescent; Adult; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Col

2006
Is once-daily mesalazine equivalent to the currently used twice-daily regimen? A study performed in 30 healthy volunteers.
    Journal of clinical pharmacology, 2007, Volume: 47, Issue:3

    Topics: Acetylglucosaminidase; Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroi

2007
Renal tubular injury is present in acute inflammatory bowel disease prior to the introduction of drug therapy.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:8

    Topics: Acetylglucosaminidase; Adult; Aged; Aged, 80 and over; Alpha-Globulins; Anti-Inflammatory Agents, No

2001
Low doses of drugs able to alter intestinal mucosal permeability to food antigens (5-aminosalicylic acid and sodium cromoglycate) do not reduce proteinuria in patients with IgA nephropathy: a preliminary noncontrolled trial.
    Nephron, 1992, Volume: 61, Issue:2

    Topics: Adult; Aminosalicylic Acids; Antigens; Cromolyn Sodium; Female; Food; Glomerulonephritis, IGA; Human

1992

Other Studies

5 other studies available for mesalamine and Proteinuria

ArticleYear
[Crohn's disease in association with IgA nephropathy].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2008, Volume: 52, Issue:2

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antimetabo

2008
Asymptomatic urinary anomalies, hematuria and proteinuria, in patients with inflammatory bowel disease. Preliminary study.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2011, Volume: 49, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Crohn Disease; Diagnosis, Diffe

2011
Microproteinuria in patients with inflammatory bowel disease: is it associated with the disease activity or the treatment with 5-aminosalicylic acid?
    World journal of gastroenterology, 2006, Feb-07, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Aged; Colitis, Ulcerative; Creatinine; Crohn Disease; Female; Humans; Inflammator

2006
Renal tubular dysfunction in patients with inflammatory bowel disease treated with aminosalicylate.
    Gut, 1997, Volume: 40, Issue:6

    Topics: Adult; Alkaline Phosphatase; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Dose-Res

1997
Pyelonephritis caused by mesalazine.
    Nephron, 2000, Volume: 86, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Blood Cell Count; Blood Sedimentation; Hematuria; Hu

2000