mesalamine has been researched along with Precancerous Conditions in 9 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Precancerous Conditions: Pathological conditions that tend eventually to become malignant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In familial and sporadic colorectal cancer, aspirin, other nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 inhibitors have been tested for their ability to reduce polyp and cancer development in clinical studies." | 2.42 | Review article: the chemoprevention of colorectal carcinoma. ( Gasche, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 3 (33.33) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Velayos, FS | 3 |
| Lee, JK | 1 |
| Jegadeesan, R | 1 |
| Navaneethan, U | 1 |
| Gutierrez, NG | 1 |
| Venkatesh, PG | 1 |
| Hammel, JP | 1 |
| Sanaka, MR | 1 |
| Shen, B | 1 |
| Lyakhovich, A | 1 |
| Gasche, C | 3 |
| Di Sabatino, A | 1 |
| Biancheri, P | 1 |
| Rovedatti, L | 1 |
| Macdonald, TT | 1 |
| Corazza, GR | 1 |
| Itzkowitz, SH | 1 |
| Harpaz, N | 1 |
| Jess, T | 1 |
| Loftus, EV | 1 |
| Winther, KV | 1 |
| Tremaine, WJ | 1 |
| Zinsmeister, AR | 1 |
| Scott Harmsen, W | 1 |
| Langholz, E | 1 |
| Binder, V | 1 |
| Munkholm, P | 1 |
| Sandborn, WJ | 1 |
| Rubin, DT | 1 |
| Cruz-Correa, MR | 1 |
| Jass, JR | 1 |
| Lichtenstein, GR | 1 |
| Montgomery, EA | 1 |
| Riddell, RH | 1 |
| Rutter, MD | 1 |
| Ullman, TA | 1 |
| Itzkowitz, S | 1 |
| Narisawa, T | 1 |
| Fukaura, Y | 1 |
| Takeba, N | 1 |
| Nakai, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Azione Chemiopreventiva Della Mesalazina Sul Cancro Del Colon-retto: Studio Pilota Per la Valutazione Degli Effetti Molecolari in Vivo Sulla Via di Segnalazione Proliferativa Della β-catenina (Official Title in Italian Language)"[NCT02077777] | Phase 2 | 21 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
| A Pilot Study to Evaluate the Applicability of the Crohn's Disease Endoscopy Index of Severity to Data Obtained by the Colonic Capsule Endoscopy in Ileocolonic Crohn's Disease[NCT01183845] | Phase 4 | 24 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for mesalamine and Precancerous Conditions
| Article | Year |
|---|---|
Systematic review: molecular chemoprevention of colorectal malignancy by mesalazine.
Topics: Cell Line, Tumor; Chemoprevention; Colorectal Neoplasms; Humans; Inflammatory Bowel Diseases; Intest | 2010 |
Recent advances in understanding ulcerative colitis.
Topics: Biopsy, Needle; Colectomy; Colitis, Ulcerative; Colorectal Neoplasms; Combined Modality Therapy; Dis | 2012 |
Diagnosis and management of dysplasia in patients with inflammatory bowel diseases.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colonoscopy; Colorectal Neoplasms; Humans; Inflammatory Bow | 2004 |
Review article: the chemoprevention of colorectal carcinoma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Chemoprevention; Chromosoma | 2004 |
Colorectal cancer prevention in inflammatory bowel disease and the role of 5-aminosalicylic acid: a clinical review and update.
Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Colorectal Neoplasms; Humans; I | 2008 |
4 other studies available for mesalamine and Precancerous Conditions
| Article | Year |
|---|---|
Endoscopic Surveillance and Dysplasia Management in IBD: Plus Ça Change, Plus C'est la Même Chose.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colonoscopy; Early Detection of Cancer | 2022 |
Pattern of Inflammation on Surveillance Colonoscopy Does Not Predict Development of Colitis-associated Neoplasia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Colitis, Ulcerative; Colonic N | 2016 |
Risk factors for colorectal neoplasia in inflammatory bowel disease: a nested case-control study from Copenhagen county, Denmark and Olmsted county, Minnesota.
Topics: Adult; Case-Control Studies; Colonoscopy; Colorectal Neoplasms; Denmark; Female; Gastrointestinal Ag | 2007 |
Chemoprevention of N-methylnitrosourea-induced colon carcinogenesis by ursodeoxycholic acid-5-aminosalicylic acid conjugate in F344 rats.
Topics: Animals; Anticarcinogenic Agents; Bile Acids and Salts; Colonic Neoplasms; Female; Mesalamine; Methy | 2002 |