mesalamine has been researched along with Pouchitis in 7 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Pouchitis: Acute INFLAMMATION in the INTESTINAL MUCOSA of the continent ileal reservoir (or pouch) in patients who have undergone ILEOSTOMY and restorative proctocolectomy (PROCTOCOLECTOMY, RESTORATIVE).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To test the hypothesis that sulfasalazine (SASP) might have a synergistic beneficial effect in acute pouchitis, by combining the anti-inflammatory activity of 5-aminosalicylic Acid and the bacteriostatic effect of sulphapyridine." | 9.14 | Pilot study: the use of sulfasalazine for the treatment of acute pouchitis. ( Belluzzi, A; Bianchi, ML; Castellani, L; Grazia, M; Roda, E; Roda, G; Rosati, G; Serrani, M; Ugolini, G, 2010) |
| "To test the hypothesis that sulfasalazine (SASP) might have a synergistic beneficial effect in acute pouchitis, by combining the anti-inflammatory activity of 5-aminosalicylic Acid and the bacteriostatic effect of sulphapyridine." | 5.14 | Pilot study: the use of sulfasalazine for the treatment of acute pouchitis. ( Belluzzi, A; Bianchi, ML; Castellani, L; Grazia, M; Roda, E; Roda, G; Rosati, G; Serrani, M; Ugolini, G, 2010) |
| "Treatment of pouchitis is largely empirical and few controlled studies have been carried-out." | 2.41 | Review article: treatment of mild to moderate ulcerative colitis and pouchitis. ( Amadini, C; Campieri, M; Gionchetti, P; Rizzello, F; Venturi, A, 2002) |
| "The incidence of PPI in patients with ulcerative colitis/indeterminate colitis is 5." | 1.35 | Incidence and short-term implications of prepouch ileitis following restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis. ( Bell, AJ; Ciclitira, PJ; Clark, SK; McLaughlin, SD; Nicholls, RJ; Tekkis, PP, 2009) |
| "Firstly we used ciprofloxacin to treat pouchitis." | 1.33 | Diffuse gastroduodenitis and pouchitis associated with ulcerative colitis. ( Hori, K; Ikeuchi, H; Kaibe, N; Nakamura, M; Nakano, H; Nishigami, T; Noda, M; Uchino, M; Yamamura, T; Yanagi, H, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersson, P | 1 |
| Norblad, R | 1 |
| Söderholm, JD | 1 |
| Myrelid, P | 1 |
| McLaughlin, SD | 1 |
| Clark, SK | 1 |
| Bell, AJ | 1 |
| Tekkis, PP | 1 |
| Ciclitira, PJ | 1 |
| Nicholls, RJ | 1 |
| Belluzzi, A | 1 |
| Serrani, M | 1 |
| Roda, G | 1 |
| Bianchi, ML | 1 |
| Castellani, L | 1 |
| Grazia, M | 1 |
| Rosati, G | 1 |
| Ugolini, G | 1 |
| Roda, E | 1 |
| Matthes, H | 1 |
| Moser, G | 1 |
| Jantschek, G | 1 |
| Böhm, S | 1 |
| Kruis, W | 1 |
| Ikeuchi, H | 1 |
| Hori, K | 1 |
| Nishigami, T | 1 |
| Nakano, H | 1 |
| Uchino, M | 1 |
| Nakamura, M | 1 |
| Kaibe, N | 1 |
| Noda, M | 1 |
| Yanagi, H | 1 |
| Yamamura, T | 1 |
| Gionchetti, P | 1 |
| Amadini, C | 1 |
| Rizzello, F | 1 |
| Venturi, A | 1 |
| Campieri, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-Blind, Placebo-Controlled Study of VSL#3 Versus Placebo in the Maintenance of Remission in Crohn's Disease[NCT00114465] | Phase 4 | 38 participants (Actual) | Interventional | 2005-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for mesalamine and Pouchitis
| Article | Year |
|---|---|
[Probiotics in chronic inflammatory bowel disease].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bifidobacterium; Colitis, Ulcerative; Crohn Disease; Escher | 2006 |
Review article: treatment of mild to moderate ulcerative colitis and pouchitis.
Topics: Administration, Oral; Administration, Rectal; Anti-Infective Agents; Anti-Inflammatory Agents; Anti- | 2002 |
1 trial available for mesalamine and Pouchitis
| Article | Year |
|---|---|
Pilot study: the use of sulfasalazine for the treatment of acute pouchitis.
Topics: Adult; Colonic Pouches; Female; Humans; Intestinal Mucosa; Male; Mesalamine; Middle Aged; Pilot Proj | 2010 |
4 other studies available for mesalamine and Pouchitis
| Article | Year |
|---|---|
Ileorectal anastomosis in comparison with ileal pouch anal anastomosis in reconstructive surgery for ulcerative colitis--a single institution experience.
Topics: Abdominal Neoplasms; Adenocarcinoma; Adolescent; Adrenal Cortex Hormones; Adult; Anastomosis, Surgic | 2014 |
Incidence and short-term implications of prepouch ileitis following restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis.
Topics: Adult; Aged; Anti-Infective Agents; Anti-Inflammatory Agents; Budesonide; Ciprofloxacin; Colitis, Ul | 2009 |
[Ulcerative colitis. Complementary therapies].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Colitis, Ulcerative; Complementary Therapies; | 2004 |
Diffuse gastroduodenitis and pouchitis associated with ulcerative colitis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Duodenitis; Female; Gastritis; | 2006 |