mesalamine has been researched along with Postoperative Complications in 24 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.
| Excerpt | Relevance | Reference |
|---|---|---|
| "At two years, 1/6 patient had clinical recurrence and 1/6 patient had endoscopic and clinical recurrence." | 2.79 | Low serum trough levels are associated with post-surgical recurrence in Crohn's disease patients undergoing prophylaxis with adalimumab. ( Baldissarro, I; Bodini, G; de Cassan, C; Dulbecco, P; Fazio, V; Giambruno, E; Peyrin-Biroulet, L; Savarino, E; Savarino, V, 2014) |
| " No clear relationship, however, has been shown between dosage and response." | 2.71 | Two mesalazine regimens in the prevention of the post-operative recurrence of Crohn's disease: a pragmatic, double-blind, randomized controlled trial. ( Annese, V; Cammà, C; Caprilli, R; Castiglione, F; Corrao, G; Cottone, M; Latella, G; Papi, C; Sturniolo, G; Tonelli, F; Viscido, A, 2003) |
| "Diarrhea is a common clinical feature of inflammatory bowel diseases and may be accompanied by abdominal pain, urgency, and fecal incontinence." | 2.48 | Diarrhea in chronic inflammatory bowel diseases. ( Wenzl, HH, 2012) |
| "Crohn's recurrence is the appearance of objective signs defined radiologically, endoscopically or pathologically of Crohn's disease in the bowel of a patient who has previously had a resection of all macroscopically diseased tissue." | 2.40 | [Drug prevention of Crohn disease recurrence in the neo-terminal ileum after ileocolic resection]. ( Rutgeerts, P; Vermeire, S, 1998) |
| "The recurrence rate of Crohn's disease after surgery is very high." | 2.40 | [Therapy of Crohn disease in internal medicine: postoperative recurrence and fistulas]. ( Blum, HE; Volk-Zeiher, BA, 1998) |
| "Gastroduodenal Crohn disease is a complex and difficult problem that is associated with serious complications and need for reoperation." | 1.30 | An audit of gastroduodenal Crohn disease: clinicopathologic features and management. ( Allan, RN; Keighley, MR; Yamamoto, T, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.17) | 18.7374 |
| 1990's | 8 (33.33) | 18.2507 |
| 2000's | 6 (25.00) | 29.6817 |
| 2010's | 7 (29.17) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Farag, AFA | 1 |
| Mostafa, M | 1 |
| Yehia Elbarmelgi, M | 1 |
| Law, CCY | 1 |
| Koh, D | 1 |
| Bao, Y | 1 |
| Jairath, V | 1 |
| Narula, N | 1 |
| Kominami, Y | 1 |
| Ohe, H | 1 |
| Higashi, R | 1 |
| Hirao, K | 1 |
| Ogawa, T | 1 |
| Nakagawa, M | 1 |
| Araki, Y | 1 |
| Mizuno, M | 1 |
| Chayama, K | 1 |
| Calafat, M | 1 |
| Mañosa, M | 1 |
| Cabré, E | 2 |
| Domènech, E | 2 |
| Bodini, G | 1 |
| Savarino, V | 1 |
| Peyrin-Biroulet, L | 1 |
| de Cassan, C | 1 |
| Dulbecco, P | 1 |
| Baldissarro, I | 1 |
| Fazio, V | 1 |
| Giambruno, E | 1 |
| Savarino, E | 1 |
| Lee, JL | 1 |
| Yu, CS | 1 |
| Lim, SB | 1 |
| Park, IJ | 1 |
| Yoon, YS | 1 |
| Kim, CW | 1 |
| Yang, SK | 1 |
| Kim, JC | 1 |
| Yamamoto, T | 3 |
| Umegae, S | 1 |
| Matsumoto, K | 1 |
| Sorrentino, D | 1 |
| Terrosu, G | 1 |
| Paviotti, A | 1 |
| Geraci, M | 1 |
| Avellini, C | 1 |
| Zoli, G | 1 |
| Fries, W | 1 |
| Danese, S | 1 |
| Occhipinti, P | 1 |
| Croatto, T | 1 |
| Zarifi, D | 1 |
| Wenzl, HH | 1 |
| Jussila, A | 1 |
| Färkkilä, M | 1 |
| Järvinen, HJ | 1 |
| Caprilli, R | 1 |
| Cottone, M | 1 |
| Tonelli, F | 1 |
| Sturniolo, G | 1 |
| Castiglione, F | 1 |
| Annese, V | 1 |
| Papi, C | 1 |
| Viscido, A | 1 |
| Cammà, C | 1 |
| Corrao, G | 1 |
| Latella, G | 1 |
| Scala, L | 1 |
| Bernal, I | 1 |
| García-Planella, E | 1 |
| Casalots, A | 1 |
| Piñol, M | 1 |
| Esteve-Comas, M | 1 |
| Boix, J | 1 |
| Gassull, MA | 1 |
| Cima, RR | 1 |
| Pemberton, JH | 1 |
| Sufiyarov, IF | 1 |
| Hallak, A | 1 |
| Baratz, M | 1 |
| Santo, M | 1 |
| Halpern, Z | 1 |
| Rabau, M | 1 |
| Werbin, N | 1 |
| Gilat, T | 1 |
| Korelitz, BI | 1 |
| Vermeire, S | 1 |
| Rutgeerts, P | 1 |
| Volk-Zeiher, BA | 1 |
| Blum, HE | 1 |
| Jauch, KW | 1 |
| Rentsch, M | 1 |
| Schölmerich, J | 1 |
| Allan, RN | 1 |
| Keighley, MR | 1 |
| Triantafillidis, JK | 1 |
| Nicolakis, D | 1 |
| Mountaneas, G | 1 |
| Pomonis, E | 1 |
| Mayberry, JF | 1 |
| Balfour, TW | 1 |
| Long, RG | 1 |
| Miglioli, M | 1 |
| Barbara, L | 1 |
| Di Febo, G | 1 |
| Gozzetti, G | 1 |
| Lauri, A | 1 |
| Paganelli, GM | 1 |
| Poggioli, G | 1 |
| Santucci, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Biologic Onset of Crohn's Disease: A Screening Study in First Degree Relatives[NCT03291743] | 38 participants (Actual) | Interventional | 2017-02-10 | Terminated (stopped due to Death of Principal Investigator) | |||
| A Pilot Study of the Safety and Efficacy of AST-120 in the Treatment of Antibiotic-Refractory Pouchitis[NCT00583531] | Phase 2 | 2 participants (Actual) | Interventional | 2007-03-31 | Terminated (stopped due to Lack of enrollment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for mesalamine and Postoperative Complications
| Article | Year |
|---|---|
Risk of Postoperative Infectious Complications From Medical Therapies in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.
Topics: Adrenal Cortex Hormones; Digestive System Surgical Procedures; Humans; Immunologic Factors; Infectio | 2020 |
Diarrhea in chronic inflammatory bowel diseases.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidiarrheals; Bacterial Infections | 2012 |
[Can the postoperative relapse of Crohn disease be influenced?].
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Clinical Trials as Top | 2001 |
Medical and surgical management of chronic ulcerative colitis.
Topics: Anastomosis, Surgical; Antibodies, Monoclonal; Chronic Disease; Colectomy; Colitis, Ulcerative; Colo | 2005 |
[Drug prevention of Crohn disease recurrence in the neo-terminal ileum after ileocolic resection].
Topics: Anti-Inflammatory Agents; Budesonide; Colon; Crohn Disease; Follow-Up Studies; Humans; Ileum; Mesala | 1998 |
[Therapy of Crohn disease in internal medicine: postoperative recurrence and fistulas].
Topics: Combined Modality Therapy; Crohn Disease; Female; Humans; Immunosuppressive Agents; Male; Mesalamine | 1998 |
[Crohn disease--principle of longitudinal therapy planning with early surgical indications].
Topics: Crohn Disease; Humans; Longitudinal Studies; Mesalamine; Patient Care Planning; Patient Care Team; P | 1998 |
4 trials available for mesalamine and Postoperative Complications
| Article | Year |
|---|---|
Low serum trough levels are associated with post-surgical recurrence in Crohn's disease patients undergoing prophylaxis with adalimumab.
Topics: Adalimumab; Adult; Aged; Antibodies, Monoclonal, Humanized; Crohn Disease; Dose-Response Relationshi | 2014 |
Impact of infliximab therapy after early endoscopic recurrence following ileocolonic resection of Crohn's disease: a prospective pilot study.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodi | 2009 |
Early diagnosis and treatment of postoperative endoscopic recurrence of Crohn's disease: partial benefit by infliximab--a pilot study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Chemoprevention; Colonoscopy | 2012 |
Two mesalazine regimens in the prevention of the post-operative recurrence of Crohn's disease: a pragmatic, double-blind, randomized controlled trial.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Dose-Response R | 2003 |
13 other studies available for mesalamine and Postoperative Complications
| Article | Year |
|---|---|
Calprotectin in Low anterior resection syndrome patients; a new insight into diagnosis and management: A pilot study.
Topics: Humans; Leukocyte L1 Antigen Complex; Mesalamine; Pilot Projects; Postoperative Complications; Quali | 2022 |
[A case of diversion colitis successfully treated with 5-aminosalicylic acid].
Topics: Aged, 80 and over; Colectomy; Colitis; Enema; Humans; Ileostomy; Male; Mesalamine; Postoperative Com | 2013 |
[Acute pericarditis associated with oral or topical mesalazine therapy in patients with ulcerative colitis].
Topics: Administration, Oral; Administration, Rectal; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agen | 2014 |
Surgical Treatment of Crohn Colitis Involving More Than 2 Colonic Segments: Long-Term Outcomes From a Single Institution.
Topics: Adult; Age of Onset; Colectomy; Colitis; Crohn Disease; Female; Humans; Immunosuppressive Agents; Ma | 2016 |
Infliximab for early endoscopic recurrence in patients with Crohn's disease.
Topics: Antibodies, Monoclonal; Colonoscopy; Crohn Disease; Female; Humans; Male; Mesalamine; Postoperative | 2012 |
[Azathioprine and mesalazine in the prevention of postsurgical recurrence of Crohn's disease: a retrospective study].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Crohn Disease; Female; Humans; Immunos | 2004 |
Experimental validation for the use of a film on the basis of modified hyaluronic acid for prevention of postoperative peritoneal adhesions.
Topics: Animals; Biocompatible Materials; Hyaluronic Acid; Materials Testing; Mesalamine; Peritoneal Disease | 2007 |
Ileitis after colectomy for ulcerative colitis or carcinoma.
Topics: Adult; Aged; Aminosalicylic Acids; Azathioprine; Colectomy; Colitis, Ulcerative; Colonic Neoplasms; | 1994 |
Drug choice in preventing postoperative Crohn's disease.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Humans; Mesalamine; Po | 1996 |
An audit of gastroduodenal Crohn disease: clinicopathologic features and management.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Child; Constriction, Pathologic; C | 1999 |
Treatment of diversion colitis with 5-aminosalicylic acid enemas: comparison with betamethasone enemas.
Topics: Aminosalicylic Acids; Betamethasone; Colitis; Enema; Female; Humans; Mesalamine; Middle Aged; Postop | 1991 |
Inflammation in the rectal stump: the role of 5-amino salicylic acid suppositories.
Topics: Adult; Aminosalicylic Acids; Colitis, Ulcerative; Female; Humans; Inflammation; Male; Mesalamine; Po | 1990 |
Topical administration of 5-aminosalicylic acid: a therapeutic proposal for the treatment of pouchitis.
Topics: Administration, Topical; Adolescent; Adult; Aminosalicylic Acids; Anal Canal; Anastomosis, Surgical; | 1989 |