Page last updated: 2024-10-30

mesalamine and Kidney Diseases

mesalamine has been researched along with Kidney Diseases in 19 studies

Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Tubular proteinuria is an extra-intestinal manifestation of inflammatory bowel disease irrespective of 5-ASA treatment."2.70Renal tubular injury is present in acute inflammatory bowel disease prior to the introduction of drug therapy. ( Fraser, JS; Lamb, EJ; Muller, AF; Newman, DJ; Smith, DJ, 2001)
"A 29-year-old male patient with ulcerative colitis, who underwent haemodialysis thrice a week because of severe renal dysfunction."1.32Sulphasalazine-induced leucopenia in a patient with renal dysfunction. ( Hino, B; Iida, M; Itoh, Y; Joh, Y; Makino, K; Oishi, R; Teshima, D; Yano, T, 2003)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's7 (36.84)18.2507
2000's8 (42.11)29.6817
2010's3 (15.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jairath, V1
Hokkanen, SRK1
Guizzetti, L1
Boxall, N1
Campbell-Hill, S1
Patel, H1
Moum, B1
Velciov, S1
Gluhovschi, G1
Sporea, I1
Trandafirescu, V1
Petrica, L1
Bozdog, G1
Gluhovschi, C1
Bob, F1
Gădălean, F1
Buzaş, R1
Bobu, M1
Voicu, L1
Zallot, C1
Billioud, V1
Frimat, L1
Faure, P1
Peyrin-Biroulet, L1
Teshima, D1
Hino, B1
Makino, K1
Yano, T1
Itoh, Y1
Joh, Y1
Iida, M1
Oishi, R1
Logan, RF2
van Staa, TP1
Siveke, JT1
Egert, J1
Sitter, T1
Schiemann, U1
Walcher, P1
Török, HP1
Glas, J1
Folwaczny, C1
Muller, AF2
Stevens, PE1
McIntyre, AS1
Ellison, H1
Gisbert, JP1
González-Lama, Y1
Maté, J1
Briggs, D1
Calder, I1
Woods, R1
Tange, J1
Rhodes, J1
Coles, GA1
Sninsky, CA1
Colombel, JF1
Brabant, G1
Gubler, MC1
Locquet, A1
Comes, MC1
Dehennault, M1
Delcroix, M1
Kreisel, W1
Wolf, LM1
Grotz, W1
Grieshaber, M1
Schreiber, S1
Hämling, J1
Zehnter, E1
Howaldt, S1
Daerr, W1
Raedler, A1
Kruis, W1
Elseviers, MM1
De Broe, ME1
Birketvedt, GS1
Berg, KJ1
Fausa, O1
Florholmen, J1
Fraser, JS1
Smith, DJ1
Newman, DJ1
Lamb, EJ1
Daneshmend, TK1

Reviews

2 reviews available for mesalamine and Kidney Diseases

ArticleYear
5-Aminosalicylates and renal function in inflammatory bowel disease: a systematic review.
    Inflammatory bowel diseases, 2007, Volume: 13, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Humans; Inflammatory Bowel Diseases; Kidney; Kidney Disea

2007
Epidemiology of toxic nephropathies.
    Advances in nephrology from the Necker Hospital, 1997, Volume: 27

    Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammatory Bowel Diseases; Kidney Dis

1997

Trials

1 trial available for mesalamine and Kidney Diseases

ArticleYear
Renal tubular injury is present in acute inflammatory bowel disease prior to the introduction of drug therapy.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:8

    Topics: Acetylglucosaminidase; Adult; Aged; Aged, 80 and over; Alpha-Globulins; Anti-Inflammatory Agents, No

2001

Other Studies

16 other studies available for mesalamine and Kidney Diseases

ArticleYear
No increased risk of nephrotoxicity associated with 5-aminosalicylic acid in IBD: a population-based cohort and nested case-control study.
    Alimentary pharmacology & therapeutics, 2019, Volume: 50, Issue:4

    Topics: Aged; Aged, 80 and over; Case-Control Studies; Cohort Studies; Colitis, Ulcerative; Crohn Disease; D

2019
Which are the 5-ASA compound side effects and how is it possible to avoid them?
    Inflammatory bowel diseases, 2008, Volume: 14 Suppl 2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Dose-Response Relationship, Drug; Female; Humans;

2008
Asymptomatic urinary anomalies, hematuria and proteinuria, in patients with inflammatory bowel disease. Preliminary study.
    Romanian journal of internal medicine = Revue roumaine de medecine interne, 2011, Volume: 49, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Crohn Disease; Diagnosis, Diffe

2011
5-Aminosalicylates and renal function monitoring in inflammatory bowel disease: a nationwide survey.
    Journal of Crohn's & colitis, 2013, Volume: 7, Issue:7

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Creatinine; Cross-Sectional Studies; France; Gastroenterolo

2013
Sulphasalazine-induced leucopenia in a patient with renal dysfunction.
    Journal of clinical pharmacy and therapeutics, 2003, Volume: 28, Issue:3

    Topics: Adult; Arylamine N-Acetyltransferase; Colitis, Ulcerative; Gastrointestinal Agents; Humans; Kidney D

2003
Sulphasalazine and mesalazine: serious adverse reactions re-evaluated on the basis of suspected adverse reaction reports to the Committee on Safety of Medicines.
    Gut, 2003, Volume: 52, Issue:10

    Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Data Interpretatio

2003
5-ASA therapy and renal function in inflammatory bowel disease.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Humans; Inflammatory Bowel Diseases; Kidney Diseases; Mesal

2005
Experience of 5-aminosalicylate nephrotoxicity in the United Kingdom.
    Alimentary pharmacology & therapeutics, 2005, May-15, Volume: 21, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Drug Monitoring; Epidemiolo

2005
The influence of metabolic variation on analgesic nephrotoxicity. Experiments with the Gunn rat.
    Pathology, 1982, Volume: 14, Issue:4

    Topics: Acetaminophen; Aminophenols; Aminosalicylic Acids; Analgesics; Animals; Aspirin; Genetic Carrier Scr

1982
An alternative view of 5-ASA formulations.
    Gut, 1995, Volume: 36, Issue:4

    Topics: Aminosalicylic Acids; Chemistry, Pharmaceutical; Humans; Inflammatory Bowel Diseases; Kidney Disease

1995
New salicylates as maintenance treatment in ulcerative colitis.
    Gut, 1995, Volume: 36, Issue:4

    Topics: Aminosalicylic Acids; Colitis, Ulcerative; Humans; Kidney Diseases; Mesalamine

1995
Renal insufficiency in infant: side-effect of prenatal exposure to mesalazine?
    Lancet (London, England), 1994, Aug-27, Volume: 344, Issue:8922

    Topics: Adult; Aminosalicylic Acids; Crohn Disease; Female; Fetus; Humans; Infant; Kidney Diseases; Male; Me

1994
Renal tubular damage: an extraintestinal manifestation of chronic inflammatory bowel disease.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, N

1996
Renal tubular dysfunction in patients with inflammatory bowel disease treated with aminosalicylate.
    Gut, 1997, Volume: 40, Issue:6

    Topics: Adult; Alkaline Phosphatase; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Dose-Res

1997
Glomerular and tubular renal functions after long-term medication of sulphasalazine, olsalazine, and mesalazine in patients with ulcerative colitis.
    Inflammatory bowel diseases, 2000, Volume: 6, Issue:4

    Topics: Adult; Aged; Aminosalicylic Acids; Colitis, Ulcerative; Female; Gastrointestinal Agents; Humans; Kid

2000
Mesalazine-associated thrombocytopenia.
    Lancet (London, England), 1991, May-25, Volume: 337, Issue:8752

    Topics: Aminosalicylic Acids; Female; Headache; Humans; Kidney Diseases; Mesalamine; Middle Aged; Thrombocyt

1991