mesalamine has been researched along with Injuries, Radiation in 13 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effectiveness of metronidazole in combination with corticosteroids in enema and mesalazine (5-aminosalicylic acid) in comparison with the same protocol without metronidazole in the treatment of chronic radiation proctitis." | 9.09 | Metronidazole in the treatment of chronic radiation proctitis: clinical trial. ( Cavcić, J; Jelincić, Z; Martinac, P; Panijan-Pezerović, R; Turcić, J; Unusić, J; Zupancić, B, 2000) |
| "To evaluate the effectiveness of metronidazole in combination with corticosteroids in enema and mesalazine (5-aminosalicylic acid) in comparison with the same protocol without metronidazole in the treatment of chronic radiation proctitis." | 5.09 | Metronidazole in the treatment of chronic radiation proctitis: clinical trial. ( Cavcić, J; Jelincić, Z; Martinac, P; Panijan-Pezerović, R; Turcić, J; Unusić, J; Zupancić, B, 2000) |
| "Balsalazide is a new-generation 5-ASA drug that yields a high concentration of active drug to the distal colon." | 2.71 | Prevention of acute radiation-induced proctosigmoiditis by balsalazide: a randomized, double-blind, placebo controlled trial in prostate cancer patients. ( Bettenhausen, D; Jahraus, CD; Malik, U; Sellitti, M; St Clair, WH, 2005) |
| "Radiation enteritis is a severe problem in patients receiving irradiation of the abdomen or pelvis in the course of cancer treatment." | 2.44 | Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review. ( Böcker, U; Singer, MV; Wenz, F; Zimmerer, T, 2008) |
| "Radiation proctitis is a common complication of pelvic radiation for which an optimal treatment remains undetermined." | 1.37 | The efficacy of the combination therapy with oral and topical mesalazine for patients with the first episode of radiation proctitis. ( Joo, HR; Kim, TG; Kim, TO; Moon, YS; Park, J; Park, MJ; Park, SH; Ryu, DY; Seo, EH; Song, GA; Yang, SY, 2011) |
| "Radiation proctitis is a well-known complication of abdominal and pelvic radiation." | 1.28 | Failure of 5-aminosalicylic acid enemas to improve chronic radiation proctitis. ( Baum, CA; Biddle, WL; Miner, PB, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goodhand, J | 1 |
| Dawson, R | 1 |
| Hefferon, M | 1 |
| Tshuma, N | 1 |
| Swanson, G | 1 |
| Wahed, M | 1 |
| Croft, NM | 1 |
| Lindsay, JO | 1 |
| Seo, EH | 1 |
| Kim, TO | 1 |
| Kim, TG | 1 |
| Joo, HR | 1 |
| Park, J | 1 |
| Park, SH | 1 |
| Yang, SY | 1 |
| Moon, YS | 1 |
| Park, MJ | 1 |
| Ryu, DY | 1 |
| Song, GA | 1 |
| Sanguineti, G | 1 |
| Franzone, P | 1 |
| Marcenaro, M | 1 |
| Foppiano, F | 1 |
| Vitale, V | 1 |
| Jahraus, CD | 2 |
| Rubin, DT | 1 |
| Scherl, EJ | 1 |
| Bettenhausen, D | 2 |
| Malik, U | 1 |
| Sellitti, M | 1 |
| St Clair, WH | 1 |
| Zimmerer, T | 1 |
| Böcker, U | 1 |
| Wenz, F | 1 |
| Singer, MV | 1 |
| Baughan, CA | 1 |
| Canney, PA | 1 |
| Buchanan, RB | 1 |
| Pickering, RM | 1 |
| Resbeut, M | 1 |
| Marteau, P | 1 |
| Cowen, D | 1 |
| Richaud, P | 1 |
| Bourdin, S | 1 |
| Dubois, JB | 1 |
| Mere, P | 1 |
| N'Guyen, TD | 1 |
| Teshima, T | 1 |
| Hanks, GE | 1 |
| Hanlon, AL | 1 |
| Peter, RS | 1 |
| Schultheiss, TE | 1 |
| Cavcić, J | 1 |
| Turcić, J | 1 |
| Martinac, P | 1 |
| Jelincić, Z | 1 |
| Zupancić, B | 1 |
| Panijan-Pezerović, R | 1 |
| Unusić, J | 1 |
| Triantafillidis, JK | 1 |
| Dadioti, P | 1 |
| Nicolakis, D | 1 |
| Mericas, E | 1 |
| Baum, CA | 1 |
| Biddle, WL | 1 |
| Miner, PB | 1 |
| Freund, U | 1 |
| Schölmerich, J | 1 |
| Siems, H | 1 |
| Kluge, F | 1 |
| Schäfer, HE | 1 |
| Wannenmacher, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Postoperative or Salvage Radiotherapy for Node Negative Prostate Cancer Following Radical Prostatectomy[NCT00969111] | 70 participants (Anticipated) | Interventional | 2009-08-31 | Recruiting | |||
| An Expanded Phase II Study of Hypofractionated Dose Intense Image Guided Proton Radiation Therapy for Low and Intermediate Risk Adenocarcinoma of the Prostate[NCT01368055] | 361 participants (Actual) | Interventional | 2011-09-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for mesalamine and Injuries, Radiation
| Article | Year |
|---|---|
Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review.
Topics: Abdominal Neoplasms; Acute Disease; Chronic Disease; Combined Modality Therapy; Controlled Clinical | 2008 |
6 trials available for mesalamine and Injuries, Radiation
| Article | Year |
|---|---|
Sucralfate versus mesalazine versus hydrocortisone in the prevention of acute radiation proctitis during conformal radiotherapy for prostate carcinoma. A randomized study.
Topics: Acute Disease; Aged; Aged, 80 and over; Contraindications; Data Interpretation, Statistical; Dose Fr | 2003 |
Prevention of acute radiation-induced proctosigmoiditis by balsalazide: a randomized, double-blind, placebo controlled trial in prostate cancer patients.
Topics: Acute Disease; Aged; Aminosalicylic Acids; Anti-Ulcer Agents; Colon, Sigmoid; Double-Blind Method; H | 2005 |
A randomized trial to assess the efficacy of 5-aminosalicylic acid for the prevention of radiation enteritis.
Topics: Aminosalicylic Acids; Diarrhea; Double-Blind Method; Enteritis; Female; Humans; Male; Mesalamine; Pe | 1993 |
A randomized double blind placebo controlled multicenter study of mesalazine for the prevention of acute radiation enteritis.
Topics: Acute Disease; Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; | 1997 |
Metronidazole in the treatment of chronic radiation proctitis: clinical trial.
Topics: Aged; Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Beta | 2000 |
Metronidazole in the treatment of chronic radiation proctitis: clinical trial.
Topics: Aged; Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Beta | 2000 |
Metronidazole in the treatment of chronic radiation proctitis: clinical trial.
Topics: Aged; Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Beta | 2000 |
Metronidazole in the treatment of chronic radiation proctitis: clinical trial.
Topics: Aged; Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Beta | 2000 |
[Unwanted side-effects in using mesalazine (5-aminosalicylic acid) during radiotherapy].
Topics: Aged; Aged, 80 and over; Aminosalicylic Acids; Clinical Trials as Topic; Double-Blind Method; Humans | 1987 |
6 other studies available for mesalamine and Injuries, Radiation
| Article | Year |
|---|---|
Inflammatory bowel disease in young people: the case for transitional clinics.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Aged; Aged, 80 and over; Antibodies, Monocl | 2010 |
The efficacy of the combination therapy with oral and topical mesalazine for patients with the first episode of radiation proctitis.
Topics: Administration, Oral; Administration, Topical; Aged; Anti-Inflammatory Agents, Non-Steroidal; Female | 2011 |
Inflammation's role in rectal cancer following prostate radiotherapy, and emerging evidence for a protective role for balsalazide.
Topics: Aminosalicylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Male; | 2005 |
Rectal bleeding after conformal 3D treatment of prostate cancer: time to occurrence, response to treatment and duration of morbidity.
Topics: Aged; Aged, 80 and over; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Gastrointest | 1997 |
High doses of 5-aminosalicylic acid enemas in chronic radiation proctitis: comparison with betamethasone enemas.
Topics: Adult; Aged; Aminosalicylic Acids; Betamethasone; Chronic Disease; Enema; Female; Humans; Mesalamine | 1990 |
Failure of 5-aminosalicylic acid enemas to improve chronic radiation proctitis.
Topics: Aminosalicylic Acids; Chronic Disease; Drug Evaluation; Enema; Female; Humans; Male; Mesalamine; Pro | 1989 |