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mesalamine and Ileitis

mesalamine has been researched along with Ileitis in 17 studies

Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.

Ileitis: Inflammation of any segment of the ILEUM and the ILEOCECAL VALVE.

Research Excerpts

ExcerptRelevanceReference
"Ninety-four patients with Crohn's ileitis (Crohn's Disease Activity Index [CDAI], 180-350) were randomly assigned to receive for 12 weeks mesalamine tablets, 4 g (35 patients); mesalamine microgranular preparation, 4 g (28 patients); and 6-methylprednisolone, 40 mg (31 patients)."9.09Mesalamine in the treatment of mild to moderate active Crohn's ileitis: results of a randomized, multicenter trial. ( Annese, V; Bianchi Porro, G; Cerutti, R; Cottone, M; Franzè, A; Pallone, F; Prantera, C, 1999)
"Ninety-four patients with Crohn's ileitis (Crohn's Disease Activity Index [CDAI], 180-350) were randomly assigned to receive for 12 weeks mesalamine tablets, 4 g (35 patients); mesalamine microgranular preparation, 4 g (28 patients); and 6-methylprednisolone, 40 mg (31 patients)."5.09Mesalamine in the treatment of mild to moderate active Crohn's ileitis: results of a randomized, multicenter trial. ( Annese, V; Bianchi Porro, G; Cerutti, R; Cottone, M; Franzè, A; Pallone, F; Prantera, C, 1999)
"The effects of 5-aminosalicylic acid (5-ASA), 4-ASA, N-acetyl-5-ASA, and sulfapyridine on mucosal permeability were determined in an experimental model of acute ileitis."3.67Sulfasalazine metabolites and dapsone attenuate formyl-methionyl-leucyl-phenylalanine-induced mucosal injury in rat ileum. ( Granger, DN; Grisham, MB; von Ritter, C, 1989)
"In patients with Crohn's colitis or ileocolitis, or in those with ileitis, no statistically significant differences were noted with respect to the relapse rates between the 5-ASA and the placebo treatment groups."2.68Mesalazine (Mesasal/Claversal) 1.5 g b.d. vs. placebo in the maintenance of remission of patients with Crohn's disease. ( Adler, M; Bailey, RJ; Rachmilewitz, D; Thomson, AB; Vatn, M; Wilson-Lynch, KA; Wright, JP, 1995)
"The incidence of PPI in patients with ulcerative colitis/indeterminate colitis is 5."1.35Incidence and short-term implications of prepouch ileitis following restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis. ( Bell, AJ; Ciclitira, PJ; Clark, SK; McLaughlin, SD; Nicholls, RJ; Tekkis, PP, 2009)
"Recurrence of Crohn's disease quite inevitably occurs after resection of distal small bowel and proximal colon, involving the neoterminal ileum close to the anastomosis."1.31Anastomotic configuration and mucosal 5-aminosalicyclic acid (5-ASA) concentrations in patients with Crohn's disease: a GISC study. Gruppo Italiano per lo Studio del Colon e del Retto. ( Andreoli, A; Annese, V; Caprilli, R; Comberlato, M; Corrao, G; Frieri, G; Palumbo, G; Pimpo, MT; Sturniolo, GC; Tonelli, F, 2000)
"Relapse was defined by CD Activity Index > or = 150, CD Endoscopic Index of Severity > or =4, and by an abnormal increase of C-reactive protein, white blood cell count, and erythrocyte sedimentation rate; moreover, if it was confirmed by x-ray and/or endoscopy."1.31Does the initial location of Crohn's disease have an influence on the time-to-relapse in patients under maintenance treatment with oral mesalamine? ( Bertoni, M; Bresci, G; Capria, A; Masolino, P; Parisi, G; Scatena, F, 2000)
"Treatment with hydroxyurea was effective in lowering the thrombocyte count."1.30[Clinical decision making in family practice. A patient with abdominal pain and chills]. ( de Meijer, PH; Meinders, AE; Schippers, EF, 1998)
"Crohn's recurrence is the appearance of objective signs--defined radiologically, endoscopically or pathologically--of Crohn's disease in the bowel of a patient who has previously had a resection of all macroscopically diseased tissue."1.29Recurrence of Crohn's disease in the neoterminal ileum after ileal resection: is prevention therapy possible? ( Rutgeerts, P, 1994)
"A patient with chronic Reiter's syndrome (RS) refractory to nonsteroidal antiinflammatory therapy was prescribed mesalamine (Pentasa) therapy for a 4-month trial."1.29Mesalamine therapy in Reiter's syndrome. ( Inman, RD; McKibbon, C; Thomson, GT, 1994)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.76)18.7374
1990's6 (35.29)18.2507
2000's8 (47.06)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Busoni, VB1
Lemale, J1
Dubern, B1
Frangi, F1
Bourgeois, P1
Orsi, M1
Badens, C1
Fabre, A1
Requena, P1
Daddaoua, A1
Martínez-Plata, E1
González, M1
Zarzuelo, A1
Suárez, MD1
Sánchez de Medina, F1
Martínez-Augustin, O1
McLaughlin, SD1
Clark, SK1
Bell, AJ1
Tekkis, PP1
Ciclitira, PJ1
Nicholls, RJ1
Tursi, A1
Brandimarte, G1
Giorgetti, G1
Nasi, G1
Prantera, C2
Bellinvia, S1
Kubota, D1
Takishima, C1
Ishii, K1
Kawamura, T1
Matsumoto, T1
Itsui, Y1
Okada, E1
Chin, S1
Oooka, S1
Tsuchiya, K1
Araki, A1
Sakamoto, N1
Miyata, T1
Kanai, T1
Watanabe, M1
Nandi, J1
Saud, B1
Zinkievich, JM1
Palma, DT1
Levine, RA1
Rutgeerts, P1
Thomson, GT1
McKibbon, C1
Inman, RD1
Hallak, A1
Baratz, M1
Santo, M1
Halpern, Z1
Rabau, M1
Werbin, N1
Gilat, T1
Thomson, AB1
Wright, JP1
Vatn, M1
Bailey, RJ1
Rachmilewitz, D1
Adler, M1
Wilson-Lynch, KA1
Schippers, EF1
de Meijer, PH1
Meinders, AE1
Cottone, M1
Pallone, F1
Annese, V2
Franzè, A1
Cerutti, R1
Bianchi Porro, G1
Frieri, G1
Pimpo, MT1
Palumbo, G1
Tonelli, F1
Sturniolo, GC1
Andreoli, A1
Comberlato, M1
Corrao, G1
Caprilli, R1
Bresci, G1
Parisi, G1
Bertoni, M1
Masolino, P1
Scatena, F1
Capria, A1
von Ritter, C1
Grisham, MB1
Granger, DN1
Verhagen, PF1
Berenschot, H1
Breteler, L1

Trials

3 trials available for mesalamine and Ileitis

ArticleYear
The suspension of an announced trial on relapse prevention in Crohn's ileitis with a 5-ASA formulation in microgranular form.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2005, Volume: 37, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Dose-Response Relationship, Drug; Double-Bli

2005
Mesalazine (Mesasal/Claversal) 1.5 g b.d. vs. placebo in the maintenance of remission of patients with Crohn's disease.
    Alimentary pharmacology & therapeutics, 1995, Volume: 9, Issue:6

    Topics: Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Canada; Colitis; Crohn D

1995
Mesalamine in the treatment of mild to moderate active Crohn's ileitis: results of a randomized, multicenter trial.
    Gastroenterology, 1999, Volume: 116, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Female; Humans; Ileitis; Italy; Male;

1999

Other Studies

14 other studies available for mesalamine and Ileitis

ArticleYear
IBD-Like Features in Syndromic Diarrhea/Trichohepatoenteric Syndrome.
    Journal of pediatric gastroenterology and nutrition, 2017, Volume: 64, Issue:1

    Topics: Anti-Inflammatory Agents; Biological Therapy; Colitis; Colon; Diarrhea; Diarrhea, Infantile; Facies;

2017
Bovine glycomacropeptide ameliorates experimental rat ileitis by mechanisms involving downregulation of interleukin 17.
    British journal of pharmacology, 2008, Volume: 154, Issue:4

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Cattle; Disease Models, Animal; Down-Regula

2008
Incidence and short-term implications of prepouch ileitis following restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis.
    Diseases of the colon and rectum, 2009, Volume: 52, Issue:5

    Topics: Adult; Aged; Anti-Infective Agents; Anti-Inflammatory Agents; Budesonide; Ciprofloxacin; Colitis, Ul

2009
Assessment of orocaecal transit time in different localization of Crohn's disease and its possible influence on clinical response to therapy.
    European journal of gastroenterology & hepatology, 2003, Volume: 15, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Breath Tests; Colitis; Crohn Disease; Delayed-

2003
[A case report: Severe bone marrow suppression caused by 6-mercaptopurin in Crohn's disease patient].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 2006, Volume: 103, Issue:9

    Topics: Abscess; Adult; Anus Diseases; Bone Marrow; Crohn Disease; Drug Therapy, Combination; Granulocyte Co

2006
5-aminosalicylic acid improves indomethacin-induced enteropathy by inhibiting iNOS transcription in rats.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Blotting, Western; Cyclooxygenase Inhi

2008
Recurrence of Crohn's disease in the neoterminal ileum after ileal resection: is prevention therapy possible?
    The Netherlands journal of medicine, 1994, Volume: 45, Issue:2

    Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Crohn Disease; Humans; Ileitis; Mesalamine; Recurren

1994
Mesalamine therapy in Reiter's syndrome.
    The Journal of rheumatology, 1994, Volume: 21, Issue:3

    Topics: Adult; Aminosalicylic Acids; Arthritis, Reactive; Colitis; Gastroenteritis; Humans; Ileitis; Male; M

1994
Ileitis after colectomy for ulcerative colitis or carcinoma.
    Gut, 1994, Volume: 35, Issue:3

    Topics: Adult; Aged; Aminosalicylic Acids; Azathioprine; Colectomy; Colitis, Ulcerative; Colonic Neoplasms;

1994
[Clinical decision making in family practice. A patient with abdominal pain and chills].
    Nederlands tijdschrift voor geneeskunde, 1998, Jun-27, Volume: 142, Issue:26

    Topics: Abdominal Pain; Aged; Aged, 80 and over; Crohn Disease; Diagnosis, Differential; Drug Therapy, Combi

1998
Anastomotic configuration and mucosal 5-aminosalicyclic acid (5-ASA) concentrations in patients with Crohn's disease: a GISC study. Gruppo Italiano per lo Studio del Colon e del Retto.
    The American journal of gastroenterology, 2000, Volume: 95, Issue:6

    Topics: Adult; Anastomosis, Surgical; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Female; Humans

2000
Does the initial location of Crohn's disease have an influence on the time-to-relapse in patients under maintenance treatment with oral mesalamine?
    Journal of clinical gastroenterology, 2000, Volume: 31, Issue:2

    Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Crohn Disease; Female

2000
Sulfasalazine metabolites and dapsone attenuate formyl-methionyl-leucyl-phenylalanine-induced mucosal injury in rat ileum.
    Gastroenterology, 1989, Volume: 96, Issue:3

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Animals; Dapsone; Ileitis; Intestinal Absorption; Intesti

1989
[Anal disorders as the initial and only expression of Crohn's disease].
    Nederlands tijdschrift voor geneeskunde, 1988, Oct-08, Volume: 132, Issue:41

    Topics: Adolescent; Adult; Aminosalicylic Acids; Anus Diseases; Crohn Disease; Female; Humans; Ileitis; Male

1988