Page last updated: 2024-10-30

mesalamine and Fibrosis

mesalamine has been researched along with Fibrosis in 8 studies

Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

ExcerptRelevanceReference
"Skin fibrosis is a complex biological remodeling process occurring in disease like systemic sclerosis, morphea, or eosinophilic fasciitis."1.62Systemic mesalazine treatment prevents spontaneous skin fibrosis in PLK2-deficient mice. ( Günther, C; Hoffmann, M; Kant, TA; Klapproth, E; Künzel, K; Künzel, SR; Newe, M; Rausch, JSE; Winter, L, 2021)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Hoffmann, M3
Kant, TA2
Emig, R1
Rausch, JSE3
Newe, M2
Schubert, M1
Künzel, K3
Winter, L2
Klapproth, E3
Peyronnet, R1
Ravens, U2
El-Armouche, A2
Künzel, SR3
Günther, C1
Weber, S1
Kämmerer, S1
Günscht, M1
Sadek, MS1
Kolanowski, T1
Meyer-Roxlau, S1
Piorkowski, C1
Tugtekin, SM1
Rose-John, S1
Yin, X1
Mayr, M1
Kuhlmann, JD1
Wimberger, P1
Grützmann, K1
Herzog, N1
Küpper, JH1
O'Reilly, M1
Kabir, SN1
Sommerfeld, LC1
Guan, K1
Wielockx, B1
Fabritz, L1
Nattel, S1
Dobrev, D1
Wagner, M1
Prado Mel, E1
Gil López, M1
Prieto, G1
Pérez-Moneo, B1
Molina, M1
Ramos, E1
Sarría, J1
Larrauri, J1
Tovar, JA1
Borum, ML1
Ginsberg, AL1
Allgayer, H1
Böhne, P1
Kruis, W1
Gaia, E1
Sambatoro, A1
De Giuli, P1
Angeli, A1

Other Studies

8 other studies available for mesalamine and Fibrosis

ArticleYear
Repurposing mesalazine against cardiac fibrosis in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:3

    Topics: Actins; Cardiotonic Agents; Cell Differentiation; Cell Line; Collagen Type I; Drug Repositioning; Ex

2021
Systemic mesalazine treatment prevents spontaneous skin fibrosis in PLK2-deficient mice.
    Naunyn-Schmiedeberg's archives of pharmacology, 2021, Volume: 394, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Differentiation; Collagen; Creatinine; Diseas

2021
Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation.
    Circulation research, 2021, Volume: 129, Issue:8

    Topics: Aged; Animals; Atrial Fibrillation; Cells, Cultured; Female; Fibrosis; Humans; Male; Mesalamine; Mic

2021
[Mesalazine-induced intersticial pneumonitis in patients with ulcerative colitis].
    Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2016, Jan-01, Volume: 40, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Fibrosis; Humans; Lung Diseases, Inter

2016
Fibrosing colonopathy associated with treatment with enteric-coated mesalazine pills.
    Inflammatory bowel diseases, 2009, Volume: 15, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Colitis, Ulcerative; Colon; Colonoscopy; Fibrosis; H

2009
Lack of evidence for fibrosing colonopathy by 5-ASA in humans.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:7

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Fibrosis; Humans; Intestinal

1999
Drug-induced fibrosing colonopathy in inflammatory bowel disease after 5-ASA?
    Digestive diseases and sciences, 1999, Volume: 44, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Fibrosis; Humans; Mesalamine; Proctocolit

1999
Adult fibrosing colonopathy associated with mesalazine treatment.
    The American journal of gastroenterology, 2001, Volume: 96, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Female; Fibrosis; Humans; Mesalamine; Mid

2001