Page last updated: 2024-10-30

mesalamine and Diarrhea

mesalamine has been researched along with Diarrhea in 77 studies

Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.

Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.

Research Excerpts

ExcerptRelevanceReference
"Some patients with inflammatory bowel disease (IBD) who were under mesalamine treatment develop adverse reactions called "mesalamine allergy," which includes high fever and worsening diarrhea."9.22Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease. ( Andoh, A; Araki, H; Fujii, T; Fujiya, M; Hanai, H; Hiraoka, S; Hisamatsu, T; Hokari, R; Ishiguro, Y; Kakuta, Y; Katsurada, T; Kawai, Y; Kinouchi, Y; Kobayashi, T; Kudo, H; Kuroha, M; Li, D; Masamune, A; Matsumoto, T; Matsuura, M; McGovern, DPB; Minegishi, N; Moroi, R; Motoya, S; Nagasaki, M; Naito, T; Nakase, H; Noguchi, M; Ohta, Y; Okamoto, D; Onodera, M; Oshima, N; Otsuka, T; Sakuraba, H; Sasaki, M; Sasaki, Y; Sato, Y; Shiga, H; Shimoyama, Y; Shinozaki, M; Suzuki, K; Suzuki, Y; Takagawa, T; Tokunaga, K, 2022)
"Twenty patients who developed diarrhea-predominant IBS after gastroenteritis were randomized to receive mesalamine (Asacol®) 1."9.16Double-blind placebo-controlled study of mesalamine in post-infective irritable bowel syndrome--a pilot study. ( Al-Suqi, M; Fang, JC; Hale, DC; Stoddard, GJ; Tuteja, AK, 2012)
"Mesalamine and/or cholestyramine may be effective for mild ICI diarrhea and colitis among patients with delayed symptom onset with lower colonic inflammatory burden."8.31Mesalamine and cholestyramine for immune checkpoint inhibitor-mediated diarrhea and colitis. ( Alasadi, M; Altan, M; Hollander, B; Jacob, JS; Khurana, S; Thomas, AS; Varatharajalu, K; Wang, J; Wang, Y; Zhao, D, 2023)
"Diarrhea was assessed at baseline and end of treatment using the Disease Activity Index (DAI)."6.72Double-blind pilot study of mesalamine vs. placebo for treatment of chronic diarrhea and nonspecific colitis in immunocompetent HIV patients. ( Fernández-Carbia, A; Marxuach-Cuétara, AM; Ríos-Bedoya, CF; Rodríguez-Orengo, JF; Rodríguez-Torres, M; Salgado-Mercado, R, 2006)
"Mesalamine suppositories have been used widely for the treatment of distal ulcerative colitis and considered to be safer than systemic administration for its limited systemic absorption."5.40Ulcerative colitis flair induced by mesalamine suppositories hypersensitivity. ( Ding, H; Hu, J; Hu, XY; Liu, XC; Mei, Q; Xu, JM, 2014)
"Some patients with inflammatory bowel disease (IBD) who were under mesalamine treatment develop adverse reactions called "mesalamine allergy," which includes high fever and worsening diarrhea."5.22Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease. ( Andoh, A; Araki, H; Fujii, T; Fujiya, M; Hanai, H; Hiraoka, S; Hisamatsu, T; Hokari, R; Ishiguro, Y; Kakuta, Y; Katsurada, T; Kawai, Y; Kinouchi, Y; Kobayashi, T; Kudo, H; Kuroha, M; Li, D; Masamune, A; Matsumoto, T; Matsuura, M; McGovern, DPB; Minegishi, N; Moroi, R; Motoya, S; Nagasaki, M; Naito, T; Nakase, H; Noguchi, M; Ohta, Y; Okamoto, D; Onodera, M; Oshima, N; Otsuka, T; Sakuraba, H; Sasaki, M; Sasaki, Y; Sato, Y; Shiga, H; Shimoyama, Y; Shinozaki, M; Suzuki, K; Suzuki, Y; Takagawa, T; Tokunaga, K, 2022)
"Twenty patients who developed diarrhea-predominant IBS after gastroenteritis were randomized to receive mesalamine (Asacol®) 1."5.16Double-blind placebo-controlled study of mesalamine in post-infective irritable bowel syndrome--a pilot study. ( Al-Suqi, M; Fang, JC; Hale, DC; Stoddard, GJ; Tuteja, AK, 2012)
"Mesalamine and/or cholestyramine may be effective for mild ICI diarrhea and colitis among patients with delayed symptom onset with lower colonic inflammatory burden."4.31Mesalamine and cholestyramine for immune checkpoint inhibitor-mediated diarrhea and colitis. ( Alasadi, M; Altan, M; Hollander, B; Jacob, JS; Khurana, S; Thomas, AS; Varatharajalu, K; Wang, J; Wang, Y; Zhao, D, 2023)
"Although oral mesalamine is the first-choice drug for treating mild-to-moderate ulcerative colitis (UC), some patients show symptoms of intolerance, including exacerbation of diarrhea and abdominal pain."4.02Multicenter survey on mesalamine intolerance in patients with ulcerative colitis. ( Fujiwara, A; Higashi, R; Hiraoka, S; Inokuchi, T; Kato, J; Matsueda, K; Miyaike, J; Moritou, Y; Okada, H; Suzuki, S; Takagi, S; Takahara, M; Toyokawa, T, 2021)
" Clinically, pro-drugs such as olsalazine have been associated with dose-dependent diarrhea, which was likely secondary to ileal secretion induced by the azo linkages, in 17% of patients."3.73Comparative analysis of the in vitro prosecretory effects of balsalazide, sulfasalazine, olsalazine, and mesalamine in rabbit distal ileum. ( Chang, EB; Hanauer, SB; Kles, KA; Musch, MW; Turner, JR; Vavricka, SR, 2005)
"Diarrhea was assessed at baseline and end of treatment using the Disease Activity Index (DAI)."2.72Double-blind pilot study of mesalamine vs. placebo for treatment of chronic diarrhea and nonspecific colitis in immunocompetent HIV patients. ( Fernández-Carbia, A; Marxuach-Cuétara, AM; Ríos-Bedoya, CF; Rodríguez-Orengo, JF; Rodríguez-Torres, M; Salgado-Mercado, R, 2006)
"Microscopic colitis is a recently recognized cause of diarrhoea, predominantly affecting older women, but its response to treatment is poorly documented."2.67Response to treatment of microscopic colitis. ( Fasoli, R; Jewell, DP, 1994)
"Microscopic colitis is a common cause of chronic watery diarrhea with a great impact on patient quality of life."2.66Treatment of microscopic colitis: the role of budesonide and new alternatives for refractory patients. ( Casanova, MJ; Gisbert, JP; Rojo, E, 2020)
"Mesalamine is a first-line drug in the treatment of inflammatory bowel diseases, while its intolerance occasionally occurs in clinical practice."2.61The culprit of mesalamine intolerance: case series and literature review. ( Fu, Y; Hong, F; Quan, R; Xie, C; Yan, W; Zou, K, 2019)
"Collagenous colitis is a cause of chronic diarrhea."2.55Interventions for treating collagenous colitis. ( Chande, N; Kafil, TS; MacDonald, JK; McDonald, JW; Nguyen, TM; Patton, PH, 2017)
"Segmental colitis associated with colonic diverticulosis is a new and emerging entity."2.48Segmental colitis associated with diverticulosis: systematic evaluation of 486 cases with meta-analysis. ( Hoda, KK; Mann, NS, 2012)
"Diarrhea is a common clinical feature of inflammatory bowel diseases and may be accompanied by abdominal pain, urgency, and fecal incontinence."2.48Diarrhea in chronic inflammatory bowel diseases. ( Wenzl, HH, 2012)
"Radiation enteritis is a severe problem in patients receiving irradiation of the abdomen or pelvis in the course of cancer treatment."2.44Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review. ( Böcker, U; Singer, MV; Wenz, F; Zimmerer, T, 2008)
"Treatment of ulcerative colitis has changed little in recent years, except for our improved ability to deliver mesalazine to the large bowel via the recent availability of several oral and rectal preparations."2.43Inflammatory bowel disease. ( Gibson, PR; Iser, J, 2005)
"The prednisolone dose was reduced to 7."1.51Case report of patient with a Cronkhite-Canada syndrome: sustained remission after treatment with corticosteroids and mesalazine. ( Drebber, U; Kaufmann, T; Kütting, F; Mertens, J; Nierhoff, D; Schulte, S; Steffen, HM; Töx, U, 2019)
" Dissolution studies of the prepared formulation conducted in simulated colonic fluid clearly demonstrated its superiority over the marketed, delayed release dosage forms of mesalamine."1.46Role of synbiotics in polysaccharide assisted colon targeted microspheres of mesalamine for the treatment of ulcerative colitis. ( Gulati, M; Kaur, R; Singh, SK, 2017)
"Eosinophilic colitis is a rare mostly self-limiting disease affecting middle-aged adults."1.40Eosinophilic colitis is a sporadic self-limited disease of middle-aged people: a population-based study. ( Alfadda, AA; Shaffer, EA; Storr, MA; Urbanski, SJ, 2014)
"Mesalamine suppositories have been used widely for the treatment of distal ulcerative colitis and considered to be safer than systemic administration for its limited systemic absorption."1.40Ulcerative colitis flair induced by mesalamine suppositories hypersensitivity. ( Ding, H; Hu, J; Hu, XY; Liu, XC; Mei, Q; Xu, JM, 2014)
"We present a case of ulcerative colitis in a pediatric liver transplant recipient."1.35De novo inflammatory bowel disease after pediatric orthotopic liver transplant: a case report. ( Bahador, A; Dehghani, SM; Eshraghian, A; Geramizadeh, B; Kakaei, F; Malek-Hosseini, SA, 2009)
"Sulfasalazine is an important therapeutic agent in the management of chronic inflammatory bowel disease (CIBD)."1.28Sulfasalazine desensitization in children and adolescents with chronic inflammatory bowel disease. ( Tolia, V, 1992)
"Collagenous colitis is a rare condition characterized clinically by chronic diarrhea and histologically by a thickened subepithelial collagenous band in colonic biopsies in an endoscopically normal colon."1.28Familial occurrence of collagenous colitis. A report of two families. ( Blok, P; Dekker, W; Lam, HG; Meuwissen, SG; Seldenrijk, CA; Stel, HV; van Tilburg, AJ, 1990)

Research

Studies (77)

TimeframeStudies, this research(%)All Research%
pre-19903 (3.90)18.7374
1990's15 (19.48)18.2507
2000's22 (28.57)29.6817
2010's31 (40.26)24.3611
2020's6 (7.79)2.80

Authors

AuthorsStudies
Zhang, L1
Wu, YB1
Dai, YK1
Liu, Q1
Ren, YJ1
Xu, SJ1
Pan, HG1
Chen, WJ1
Li, RL1
Hu, L1
Hollander, B1
Khurana, S1
Jacob, JS1
Altan, M1
Wang, J1
Zhao, D1
Varatharajalu, K1
Alasadi, M1
Thomas, AS1
Wang, Y1
Dai, C1
Jiang, M1
Huang, YH1
Rojo, E1
Casanova, MJ1
Gisbert, JP1
Hiraoka, S2
Fujiwara, A1
Toyokawa, T1
Higashi, R1
Moritou, Y1
Takagi, S1
Matsueda, K1
Suzuki, S1
Miyaike, J1
Inokuchi, T1
Takahara, M1
Kato, J1
Okada, H1
Suzuki, K1
Kakuta, Y1
Naito, T1
Takagawa, T1
Hanai, H1
Araki, H1
Sasaki, Y1
Sakuraba, H1
Sasaki, M1
Hisamatsu, T1
Motoya, S1
Matsumoto, T1
Onodera, M1
Ishiguro, Y1
Nakase, H1
Andoh, A1
Shinozaki, M1
Fujii, T1
Katsurada, T1
Kobayashi, T2
Fujiya, M1
Otsuka, T1
Oshima, N1
Suzuki, Y1
Sato, Y1
Hokari, R1
Noguchi, M1
Ohta, Y1
Matsuura, M1
Kawai, Y1
Tokunaga, K1
Nagasaki, M1
Kudo, H1
Minegishi, N1
Okamoto, D1
Shimoyama, Y1
Moroi, R1
Kuroha, M1
Shiga, H1
Li, D1
McGovern, DPB1
Kinouchi, Y1
Masamune, A1
Kafil, TS1
Nguyen, TM1
Patton, PH1
MacDonald, JK1
Chande, N1
McDonald, JW1
Yamauchi, R1
Araki, T1
Mitsuyama, K1
Tokito, T1
Ishii, H1
Yoshioka, S1
Kuwaki, K1
Mori, A1
Yoshimura, T1
Tsuruta, O1
Torimura, T1
Schulte, S2
Kütting, F1
Mertens, J1
Kaufmann, T1
Drebber, U1
Nierhoff, D1
Töx, U1
Steffen, HM1
Viazis, N1
Pontas, C1
Karmiris, K1
Dimas, I1
Fragaki, M1
Paspatis, G1
Drygiannakis, I1
Koutroubakis, IE1
Moschovis, D1
Tzouvala, M1
Theocharis, G1
Tsolias, C1
Thomopoulos, K1
Zampeli, E1
Axiaris, G1
Michopoulos, S1
Belesiotou, E1
Banasa, M1
Maraki, S1
Kouskoumpekou, F1
Apostolopoulos, G1
Stamouli, V1
Prifti, H1
Mantzaris, GJ1
Xie, C1
Quan, R1
Hong, F1
Zou, K1
Yan, W1
Fu, Y1
Mann, NS1
Hoda, KK1
Li, SL1
Li, C1
Alfadda, AA1
Shaffer, EA1
Urbanski, SJ1
Storr, MA1
Ding, H1
Liu, XC1
Mei, Q1
Xu, JM1
Hu, XY1
Hu, J1
Ninan, S1
Hamlin, J1
Lam, C2
Tan, W1
Leighton, M1
Hastings, M1
Lingaya, M1
Falcone, Y1
Zhou, X2
Xu, L1
Whorwell, P1
Walls, AF1
Zaitoun, A1
Montgomery, A1
Spiller, R1
Schorr, M1
Vaidya, A1
Todd, DJ1
Conant, A1
Min, T1
Ford, AC1
Green, EK1
Ambrose, LR1
Webster, DP1
Atkinson, C1
Griffiths, P1
Murray, CD1
Goodman, AL1
Mellinger, JL1
Pletneva, M1
Fontana, RJ1
Törnblom, H1
Simrén, M1
Chang, K1
Le Sessions, C1
Shillingford, N1
Lakhole, A1
Ferdman, R1
Otani, I1
Oka, S1
Tanaka, S1
Kaur, R1
Gulati, M1
Singh, SK1
Busoni, VB1
Lemale, J1
Dubern, B1
Frangi, F1
Bourgeois, P1
Orsi, M1
Badens, C1
Fabre, A1
Moum, B1
Minor, DR1
Chin, K1
Kashani-Sabet, M1
Dehghani, SM1
Eshraghian, A1
Bahador, A1
Kakaei, F1
Geramizadeh, B1
Malek-Hosseini, SA1
Lawlor, G1
Ahmed, A1
Moss, AC1
Calabrese, C1
Gionchetti, P2
Liguori, G1
Areni, A1
Fornarini, GS1
Campieri, M2
Rizzello, F1
Andrews, CN1
Griffiths, TA1
Kaufman, J1
Vergnolle, N1
Surette, MG1
Rioux, KP1
Farup, PG1
Denız, K1
Coban, G1
Ozbakir, O1
Denız, E1
Strate, LL1
Modi, R1
Cohen, E1
Spiegel, BM1
Tuteja, AK1
Fang, JC1
Al-Suqi, M1
Stoddard, GJ1
Hale, DC1
Braun, S1
Budak, K1
Vavricka, S1
Wenzl, HH1
Xue, L1
Huang, Z1
Chen, W1
Leighton, MP1
Mehta, S1
Spiller, RC1
Jani, AL1
Hamilos, D1
Hartwich, SA1
Regueiro, MD1
Kles, KA1
Vavricka, SR1
Turner, JR1
Musch, MW1
Hanauer, SB1
Chang, EB1
Gibson, PR1
Iser, J1
Rodríguez-Torres, M1
Rodríguez-Orengo, JF1
Ríos-Bedoya, CF1
Fernández-Carbia, A1
Salgado-Mercado, R1
Marxuach-Cuétara, AM1
Biancone, L1
Blanco, Gdel V1
Orlando, A1
Annese, V1
Papi, C1
Sostegni, R1
D'Incà, R1
Petruzziello, C1
Casa, A1
Sica, G1
Calabrese, E1
Pallone, F1
de la Iglesia Fanjul, I1
de Castro Losa, MR1
Izquierdo García, F1
Freeman, HJ1
Shikuwa, S1
Matuoka, Y1
Ito, M1
Isomoto, H1
Kohno, S1
Zimmerer, T1
Böcker, U1
Wenz, F1
Singer, MV1
Austin, CA1
Cann, PA1
Jones, TH1
Holdsworth, CD1
Zins, BJ1
Sandborn, WJ1
Tremaine, WJ1
Fasoli, R1
Jewell, DP1
Scheurlen, C1
Allgayer, H1
Kruis, W1
Erdmann, E1
Sauerbruch, T1
Baughan, CA1
Canney, PA1
Buchanan, RB1
Pickering, RM1
Veldman, W1
van Beek, M1
Keuning, JJ1
Driessen, WM1
Resbeut, M1
Marteau, P1
Cowen, D1
Richaud, P1
Bourdin, S1
Dubois, JB1
Mere, P1
N'Guyen, TD1
Fine, KD1
Sarles, HE1
Cryer, B1
Robert, FS1
Rao, JP1
Kang, G1
Balasubramanian, KA1
Koshi, R1
Mathan, MM1
Mathan, VI1
Wenzl, TG1
Kusenbach, G1
Skopnik, H1
Bonner, GF1
Petras, RE1
Cheong, DM1
Grewal, ID1
Breno, S1
Ruderman, WB1
Goldstein, F1
DiMarino, AJ1
Abdo, AA1
Zetler, PJ1
Halparin, LS1
Iofel, E1
Chawla, A1
Daum, F1
Markowitz, J1
García-Martín, F1
Sánchez Heras, M1
Sánchez Martínez, L1
Rodríguez-Zapata, M1
Tolia, V1
Butt, JH1
Rijk, MC1
van Schaik, A1
van Tongeren, JH1
Kristensen, KS1
Høegholm, A1
Bohr, L1
Friis, S1
van Tilburg, AJ1
Lam, HG1
Seldenrijk, CA1
Stel, HV1
Blok, P1
Dekker, W1
Meuwissen, SG1
O'Mahony, S1
Nawroz, IM1
Ferguson, A1
Donowitz, M1
Järnerot, G1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Mode of Action of Mesalazine in the Treatment of Diarrhoea-predominant Irritable Bowel Syndrome (IBS-D).[NCT01316718]Phase 4108 participants (Actual)Interventional2011-03-31Completed
[NCT02003807]102 participants (Actual)Observational2013-07-31Completed
Multicentre Controlled, Randomized Clinical Trial to Compare the Efficacy and Safety of Ambulatory Treatment of Mild Acute Diverticulitis Without Antibiotics With the Standard Treatment With Antibiotics[NCT02785549]Phase 4480 participants (Actual)Interventional2016-11-30Completed
Prevalence of Segmental Colitis Associated With Colic Diverticulosis (SCAD): an Observational Study[NCT04279821]50 participants (Anticipated)Observational2020-02-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for mesalamine and Diarrhea

ArticleYear
Efficacy and safety of Qingre-Chushi therapies in active ulcerative colitis: A network meta-analysis.
    PloS one, 2021, Volume: 16, Issue:9

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Databases, Factu

2021
Treatment of microscopic colitis: the role of budesonide and new alternatives for refractory patients.
    Revista espanola de enfermedades digestivas, 2020, Volume: 112, Issue:1

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antidiarrheals; Antimetabolites; Azathioprine; Bi

2020
Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease.
    Inflammatory bowel diseases, 2022, 01-05, Volume: 28, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Diarrhea; Genetic Background; Genome-W

2022
Interventions for treating collagenous colitis.
    The Cochrane database of systematic reviews, 2017, 11-11, Volume: 11

    Topics: Bismuth; Boswellia; Budesonide; Cholestyramine Resin; Chronic Disease; Colitis, Collagenous; Diarrhe

2017
The characteristics of nivolumab-induced colitis: an evaluation of three cases and a literature review.
    BMC gastroenterology, 2018, Aug-31, Volume: 18, Issue:1

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antineoplastic Agents; Coliti

2018
The culprit of mesalamine intolerance: case series and literature review.
    BMC gastroenterology, 2019, Jul-31, Volume: 19, Issue:1

    Topics: Abdominal Pain; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Diarrhea; Drug Eruptio

2019
Segmental colitis associated with diverticulosis: systematic evaluation of 486 cases with meta-analysis.
    Hepato-gastroenterology, 2012, Volume: 59, Issue:119

    Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Biopsy; Colitis; Colonosco

2012
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
    The American journal of gastroenterology, 2012, Volume: 107, Issue:10

    Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No

2012
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
    The American journal of gastroenterology, 2012, Volume: 107, Issue:10

    Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No

2012
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
    The American journal of gastroenterology, 2012, Volume: 107, Issue:10

    Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No

2012
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
    The American journal of gastroenterology, 2012, Volume: 107, Issue:10

    Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No

2012
Diarrhea in chronic inflammatory bowel diseases.
    Gastroenterology clinics of North America, 2012, Volume: 41, Issue:3

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidiarrheals; Bacterial Infections

2012
Diagnosis and treatment of ulcerative proctitis.
    Journal of clinical gastroenterology, 2004, Volume: 38, Issue:9

    Topics: Acute Disease; Diagnosis, Differential; Diarrhea; Hemorrhage; Humans; Mesalamine; Proctocolitis; Rec

2004
Inflammatory bowel disease.
    Australian family physician, 2005, Volume: 34, Issue:4

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colonoscopy;

2005
Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review.
    Zeitschrift fur Gastroenterologie, 2008, Volume: 46, Issue:5

    Topics: Abdominal Neoplasms; Acute Disease; Chronic Disease; Combined Modality Therapy; Controlled Clinical

2008
Collagenous and lymphocytic colitis: subject review and therapeutic alternatives.
    The American journal of gastroenterology, 1995, Volume: 90, Issue:9

    Topics: Algorithms; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Colitis;

1995
Outpatient management of inflammatory bowel disease. Let's keep it as simple as possible.
    Postgraduate medicine, 1992, Nov-01, Volume: 92, Issue:6

    Topics: Abdominal Pain; Adrenal Cortex Hormones; Ambulatory Care; Aminosalicylic Acids; Anus Diseases; Diarr

1992
Clinical tolerance of olsalazine.
    Scandinavian journal of gastroenterology. Supplement, 1988, Volume: 148

    Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Diarrhea; Humans; Mesalamine

1988

Trials

11 trials available for mesalamine and Diarrhea

ArticleYear
A mechanistic multicentre, parallel group, randomised placebo-controlled trial of mesalazine for the treatment of IBS with diarrhoea (IBS-D).
    Gut, 2016, Volume: 65, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Double-Blind Method; Drug Administra

2016
Clinical course of microscopic colitis in a single-center cohort study.
    Journal of Crohn's & colitis, 2011, Volume: 5, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Cholestyramine Resin; Coho

2011
Double-blind placebo-controlled study of mesalamine in post-infective irritable bowel syndrome--a pilot study.
    Scandinavian journal of gastroenterology, 2012, Volume: 47, Issue:10

    Topics: Abdominal Pain; Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Diarrhea; Dou

2012
Efficacy and mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D): study protocol for a randomised controlled trial.
    Trials, 2013, Jan-09, Volume: 14

    Topics: Abdominal Pain; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Clinical Protocols; Defecation; Dia

2013
Double-blind pilot study of mesalamine vs. placebo for treatment of chronic diarrhea and nonspecific colitis in immunocompetent HIV patients.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Chronic Disease; Colitis; Colonoscopy; Diarr

2006
Beclomethasone dipropionate versus mesalazine in distal ulcerative colitis: a multicenter, randomized, double-blind study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2007, Volume: 39, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents; Beclomethasone; Colitis, Ulcerative; Colonoscopy; Diarrhea; D

2007
Response to treatment of microscopic colitis.
    The Italian journal of gastroenterology, 1994, Volume: 26, Issue:5

    Topics: Aminosalicylic Acids; Colitis; Colon; Diarrhea; Drug Therapy, Combination; Eosinophils; Female; Foll

1994
A randomized trial to assess the efficacy of 5-aminosalicylic acid for the prevention of radiation enteritis.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1993, Volume: 5, Issue:1

    Topics: Aminosalicylic Acids; Diarrhea; Double-Blind Method; Enteritis; Female; Humans; Male; Mesalamine; Pe

1993
A randomized double blind placebo controlled multicenter study of mesalazine for the prevention of acute radiation enteritis.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1997, Volume: 44, Issue:1

    Topics: Acute Disease; Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea;

1997
Disposition of mesalazine from mesalazine-delivering drugs in patients with inflammatory bowel disease, with and without diarrhoea.
    Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:10

    Topics: Adult; Aged; Aminosalicylic Acids; Delayed-Action Preparations; Diarrhea; Drug Carriers; Feces; Fema

1992
Clinical tolerance of olsalazine.
    Scandinavian journal of gastroenterology. Supplement, 1988, Volume: 148

    Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Diarrhea; Humans; Mesalamine

1988

Other Studies

52 other studies available for mesalamine and Diarrhea

ArticleYear
Mesalamine and cholestyramine for immune checkpoint inhibitor-mediated diarrhea and colitis.
    Journal of cancer research and clinical oncology, 2023, Volume: 149, Issue:7

    Topics: Adult; Cholestyramine Resin; Colitis; Diarrhea; Female; Humans; Immune Checkpoint Inhibitors; Immuno

2023
Efficacy of Mesalamine in Irritable Bowel Syndrome.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2023, Volume: 21, Issue:13

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Humans; Irritable Bowel Syndrome; Mesalamine

2023
Multicenter survey on mesalamine intolerance in patients with ulcerative colitis.
    Journal of gastroenterology and hepatology, 2021, Volume: 36, Issue:1

    Topics: Abdominal Pain; Administration, Oral; Adult; Colitis, Ulcerative; Diarrhea; Disease Progression; Fem

2021
Case report of patient with a Cronkhite-Canada syndrome: sustained remission after treatment with corticosteroids and mesalazine.
    BMC gastroenterology, 2019, Feb-27, Volume: 19, Issue:1

    Topics: Aged; Alopecia; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Diarrhea; Drug Adm

2019
Prevalence of Clostridium difficile infection among hospitalized inflammatory bowel disease patients in Greece.
    European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Bacteri

2019
Vulvar swelling, plaques, and nodules in a young adult woman.
    JAMA, 2013, Jun-26, Volume: 309, Issue:24

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Constipation; Crohn Disease; Diagnosis, Diff

2013
Eosinophilic colitis is a sporadic self-limited disease of middle-aged people: a population-based study.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2014, Volume: 16, Issue:2

    Topics: Abdominal Pain; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Colitis; Colon

2014
Ulcerative colitis flair induced by mesalamine suppositories hypersensitivity.
    World journal of gastroenterology, 2014, Apr-07, Volume: 20, Issue:13

    Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colonoscopy; Di

2014
The young patient with acute bloody diarrhoea.
    Acute medicine, 2014, Volume: 13, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; C-Reactive Pro

2014
Interactive medical case. A man with diarrhea and back pain.
    The New England journal of medicine, 2015, Apr-09, Volume: 372, Issue:15

    Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents; Back Pain; Colitis, Ulcerative; Colon; Colonoscopy;

2015
Efficacy of mesalazine in IBS.
    Gut, 2016, Volume: 65, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Female; Humans; Irritable Bowel Syndrome; Male; M

2016
Intractable diarrhoea despite immune reconstitution in an HIV positive man.
    Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2015, Volume: 69

    Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; CD4 Lymphocyte Count; Cytomeg

2015
New Onset Bloody Diarrhea in a Liver Transplant Recipient. New Onset Bloody Diarrhea in a Liver Transplant Recipient.
    Gastroenterology, 2015, Volume: 149, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Diarrhea; Gastrointestinal Hemorrhage;

2015
In search for a disease-modifying treatment in irritable bowel syndrome.
    Gut, 2016, Volume: 65, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Female; Humans; Irritable Bowel Syndrome; Male; M

2016
Blood and guts: a case of early childhood Crohn's disease.
    Hospital pediatrics, 2016, Volume: 6, Issue:4

    Topics: Anti-Inflammatory Agents; Biopsy; Child, Preschool; Colonoscopy; Crohn Disease; Diagnosis, Different

2016
Mesalazine-induced enteritis causing refractory diarrhea.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2017, Volume: 29, Issue:1

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Endoscopy; Enteritis; Female; Humans; Mesal

2017
Role of synbiotics in polysaccharide assisted colon targeted microspheres of mesalamine for the treatment of ulcerative colitis.
    International journal of biological macromolecules, 2017, Volume: 95

    Topics: Animals; Body Weight; Colitis, Ulcerative; Colon; Diarrhea; Drug Carriers; Drug Liberation; Feces; F

2017
IBD-Like Features in Syndromic Diarrhea/Trichohepatoenteric Syndrome.
    Journal of pediatric gastroenterology and nutrition, 2017, Volume: 64, Issue:1

    Topics: Anti-Inflammatory Agents; Biological Therapy; Colitis; Colon; Diarrhea; Diarrhea, Infantile; Facies;

2017
Which are the 5-ASA compound side effects and how is it possible to avoid them?
    Inflammatory bowel diseases, 2008, Volume: 14 Suppl 2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Dose-Response Relationship, Drug; Female; Humans;

2008
Infliximab in the treatment of anti-CTLA4 antibody (ipilimumab) induced immune-related colitis.
    Cancer biotherapy & radiopharmaceuticals, 2009, Volume: 24, Issue:3

    Topics: Algorithms; Antibodies, Monoclonal; Antigens, CD; Clinical Trials as Topic; Colitis; CTLA-4 Antigen;

2009
De novo inflammatory bowel disease after pediatric orthotopic liver transplant: a case report.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2009, Volume: 7, Issue:3

    Topics: Adolescent; Anti-Inflammatory Agents; Biopsy; Chronic Disease; Colitis, Ulcerative; Colon; Colonosco

2009
Once-daily mesalamine granules for ulcerative colitis.
    Expert review of clinical immunology, 2010, Volume: 6, Issue:4

    Topics: Abdominal Pain; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Colitis, Ulcerati

2010
Mesalazine (5-aminosalicylic acid) alters faecal bacterial profiles, but not mucosal proteolytic activity in diarrhoea-predominant irritable bowel syndrome.
    Alimentary pharmacology & therapeutics, 2011, Volume: 34, Issue:3

    Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Diarrhea; DNA, Bacterial; F

2011
Questions about mesalazine and the irritable bowel syndrome.
    Alimentary pharmacology & therapeutics, 2011, Volume: 34, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Feces; Female; Humans; Intestinal Mucosa; Irritab

2011
Pseudomembranous collagenous colitis.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2012, Volume: 23, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Collagenous; Colonoscopy; Diarrhea; Enterocolitis,

2012
[Probiotics in gastrointestinal diseases].
    Praxis, 2012, Aug-22, Volume: 101, Issue:17

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Combined Modality Therapy; Coop

2012
The possible effects of mesalazine on the intestinal microbiota.
    Alimentary pharmacology & therapeutics, 2012, Volume: 36, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Feces; Female; Humans; Intestinal Mucosa; Irritab

2012
Bloody diarrhea, fever, and pancytopenia in a patient with active ulcerative colitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:4

    Topics: Antibodies, Antineutrophil Cytoplasmic; Antibodies, Antinuclear; Autoantigens; Autoimmune Diseases;

2003
You're the flight surgeon. Ulcerative colitis.
    Aviation, space, and environmental medicine, 2004, Volume: 75, Issue:1

    Topics: Adult; Aerospace Medicine; Anti-Inflammatory Agents, Non-Steroidal; Colic; Colitis, Ulcerative; Diag

2004
You're the flight surgeon. Crohn's disease.
    Aviation, space, and environmental medicine, 2004, Volume: 75, Issue:8

    Topics: Abdominal Pain; Adult; Aerospace Medicine; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; D

2004
Comparative analysis of the in vitro prosecretory effects of balsalazide, sulfasalazine, olsalazine, and mesalamine in rabbit distal ileum.
    Inflammatory bowel diseases, 2005, Volume: 11, Issue:3

    Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Colitis,

2005
[Collagenous colitis. Clinicopathological study of 18 cases].
    Revista clinica espanola, 2007, Volume: 207, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; B

2007
Natural history and long-term clinical behavior of segmental colitis associated with diverticulosis (SCAD syndrome).
    Digestive diseases and sciences, 2008, Volume: 53, Issue:9

    Topics: Abdominal Pain; Adult; Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Dia

2008
Cobblestone appearance in the colon of a 24-year-old man.
    Gut, 2008, Volume: 57, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Combined Modality Therapy; Diarrhe

2008
Exacerbation of diarrhoea and pain in patients treated with 5-aminosalicylic acid for ulcerative colitis.
    Lancet (London, England), 1984, Apr-21, Volume: 1, Issue:8382

    Topics: Acute Disease; Adolescent; Adult; Aminosalicylic Acids; Colitis, Ulcerative; Diarrhea; Female; Human

1984
Effect of olsalazine and mesalazine on human ileal and colonic (Na+ + K+)-ATPase. A possible diarrhogenic factor?
    The Clinical investigator, 1993, Volume: 71, Issue:4

    Topics: Aminosalicylic Acids; Binding, Competitive; Colon, Sigmoid; Diarrhea; Humans; Ileum; Inflammatory Bo

1993
Regional enteritis complicating malignant lymphoma.
    The Netherlands journal of medicine, 1996, Volume: 49, Issue:2

    Topics: Adult; Aminosalicylic Acids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti

1996
Diarrhea associated with mesalamine in a patient with chronic nongranulomatous enterocolitis.
    The New England journal of medicine, 1998, Mar-26, Volume: 338, Issue:13

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diarrhea; Dinoprostone; Enterocolitis; Fec

1998
Mechanism of purgative effect of magnesium sulphate on mouse colon.
    Journal of diarrhoeal diseases research, 1997, Volume: 15, Issue:4

    Topics: Animals; Anthracenes; Cathartics; Chloride Channels; Colon; Diarrhea; Disease Models, Animal; Drug I

1997
Salicylate inhibits fimbriae mediated HEp-2 cell adherence of and haemagglutination by enteroaggregative Escherichia coli.
    FEMS microbiology letters, 1998, Sep-15, Volume: 166, Issue:2

    Topics: Adult; Bacterial Adhesion; Bacterial Outer Membrane Proteins; Child; Diarrhea; Epithelial Cells; Ery

1998
Pseudomembranous viral colitis.
    Journal of pediatric gastroenterology and nutrition, 2000, Volume: 30, Issue:4

    Topics: Adenoviridae; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Viral; Child, Preschool; Colonoscop

2000
Short- and long-term follow-up of treatment for lymphocytic and collagenous colitis.
    Inflammatory bowel diseases, 2000, Volume: 6, Issue:2

    Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Collagen; Diarrhea

2000
Diarrhea as a side effect of mesalamine treatment for inflammatory bowel disease.
    Journal of clinical gastroenterology, 2000, Volume: 31, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Female; Humans; Inflammatory Bowel Disease

2000
Familial microscopic colitis.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2001, Volume: 15, Issue:5

    Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Colitis; Colonoscopy; Consti

2001
Oral balsalazide (Colazal) for ulcerative colitis.
    The Medical letter on drugs and therapeutics, 2001, Jul-23, Volume: 43, Issue:1109

    Topics: Abdominal Pain; Administration, Oral; Aminosalicylic Acids; Anti-Ulcer Agents; Colitis, Ulcerative;

2001
Mesalamine intolerance mimics symptoms of active inflammatory bowel disease.
    Journal of pediatric gastroenterology and nutrition, 2002, Volume: 34, Issue:1

    Topics: Abdominal Pain; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Female; Humans; Infla

2002
[Nephrogenic diabetes insipidus secondary to chronic interstitial nephritis associated with mesalazine therapy].
    Revista clinica espanola, 2002, Volume: 202, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diabetes Insipidus, Nephrogenic; Di

2002
Sulfasalazine desensitization in children and adolescents with chronic inflammatory bowel disease.
    The American journal of gastroenterology, 1992, Volume: 87, Issue:8

    Topics: Adolescent; Aminosalicylic Acids; Child; Chronic Disease; Desensitization, Immunologic; Diarrhea; Do

1992
Fatal myocarditis associated with mesalazine.
    Lancet (London, England), 1990, Mar-10, Volume: 335, Issue:8689

    Topics: Adult; Aminosalicylic Acids; Diarrhea; Female; Humans; Mesalamine; Myocarditis

1990
Familial occurrence of collagenous colitis. A report of two families.
    Journal of clinical gastroenterology, 1990, Volume: 12, Issue:3

    Topics: Adult; Aged; Aminosalicylic Acids; Biopsy; Colitis; Collagen; Diarrhea; Female; Humans; Intestinal M

1990
Coeliac disease and collagenous colitis.
    Postgraduate medical journal, 1990, Volume: 66, Issue:773

    Topics: Adult; Aminosalicylic Acids; Celiac Disease; Colitis; Diarrhea; Humans; Jejunum; Male; Mesalamine; R

1990
Arachidonic acid metabolites and their role in inflammatory bowel disease. An update requiring addition of a pathway.
    Gastroenterology, 1985, Volume: 88, Issue:2

    Topics: Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Biological Transport; Bradykinin; Colitis

1985