mesalamine has been researched along with Diarrhea in 77 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Some patients with inflammatory bowel disease (IBD) who were under mesalamine treatment develop adverse reactions called "mesalamine allergy," which includes high fever and worsening diarrhea." | 9.22 | Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease. ( Andoh, A; Araki, H; Fujii, T; Fujiya, M; Hanai, H; Hiraoka, S; Hisamatsu, T; Hokari, R; Ishiguro, Y; Kakuta, Y; Katsurada, T; Kawai, Y; Kinouchi, Y; Kobayashi, T; Kudo, H; Kuroha, M; Li, D; Masamune, A; Matsumoto, T; Matsuura, M; McGovern, DPB; Minegishi, N; Moroi, R; Motoya, S; Nagasaki, M; Naito, T; Nakase, H; Noguchi, M; Ohta, Y; Okamoto, D; Onodera, M; Oshima, N; Otsuka, T; Sakuraba, H; Sasaki, M; Sasaki, Y; Sato, Y; Shiga, H; Shimoyama, Y; Shinozaki, M; Suzuki, K; Suzuki, Y; Takagawa, T; Tokunaga, K, 2022) |
| "Twenty patients who developed diarrhea-predominant IBS after gastroenteritis were randomized to receive mesalamine (Asacol®) 1." | 9.16 | Double-blind placebo-controlled study of mesalamine in post-infective irritable bowel syndrome--a pilot study. ( Al-Suqi, M; Fang, JC; Hale, DC; Stoddard, GJ; Tuteja, AK, 2012) |
| "Mesalamine and/or cholestyramine may be effective for mild ICI diarrhea and colitis among patients with delayed symptom onset with lower colonic inflammatory burden." | 8.31 | Mesalamine and cholestyramine for immune checkpoint inhibitor-mediated diarrhea and colitis. ( Alasadi, M; Altan, M; Hollander, B; Jacob, JS; Khurana, S; Thomas, AS; Varatharajalu, K; Wang, J; Wang, Y; Zhao, D, 2023) |
| "Diarrhea was assessed at baseline and end of treatment using the Disease Activity Index (DAI)." | 6.72 | Double-blind pilot study of mesalamine vs. placebo for treatment of chronic diarrhea and nonspecific colitis in immunocompetent HIV patients. ( Fernández-Carbia, A; Marxuach-Cuétara, AM; Ríos-Bedoya, CF; Rodríguez-Orengo, JF; Rodríguez-Torres, M; Salgado-Mercado, R, 2006) |
| "Mesalamine suppositories have been used widely for the treatment of distal ulcerative colitis and considered to be safer than systemic administration for its limited systemic absorption." | 5.40 | Ulcerative colitis flair induced by mesalamine suppositories hypersensitivity. ( Ding, H; Hu, J; Hu, XY; Liu, XC; Mei, Q; Xu, JM, 2014) |
| "Some patients with inflammatory bowel disease (IBD) who were under mesalamine treatment develop adverse reactions called "mesalamine allergy," which includes high fever and worsening diarrhea." | 5.22 | Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease. ( Andoh, A; Araki, H; Fujii, T; Fujiya, M; Hanai, H; Hiraoka, S; Hisamatsu, T; Hokari, R; Ishiguro, Y; Kakuta, Y; Katsurada, T; Kawai, Y; Kinouchi, Y; Kobayashi, T; Kudo, H; Kuroha, M; Li, D; Masamune, A; Matsumoto, T; Matsuura, M; McGovern, DPB; Minegishi, N; Moroi, R; Motoya, S; Nagasaki, M; Naito, T; Nakase, H; Noguchi, M; Ohta, Y; Okamoto, D; Onodera, M; Oshima, N; Otsuka, T; Sakuraba, H; Sasaki, M; Sasaki, Y; Sato, Y; Shiga, H; Shimoyama, Y; Shinozaki, M; Suzuki, K; Suzuki, Y; Takagawa, T; Tokunaga, K, 2022) |
| "Twenty patients who developed diarrhea-predominant IBS after gastroenteritis were randomized to receive mesalamine (Asacol®) 1." | 5.16 | Double-blind placebo-controlled study of mesalamine in post-infective irritable bowel syndrome--a pilot study. ( Al-Suqi, M; Fang, JC; Hale, DC; Stoddard, GJ; Tuteja, AK, 2012) |
| "Mesalamine and/or cholestyramine may be effective for mild ICI diarrhea and colitis among patients with delayed symptom onset with lower colonic inflammatory burden." | 4.31 | Mesalamine and cholestyramine for immune checkpoint inhibitor-mediated diarrhea and colitis. ( Alasadi, M; Altan, M; Hollander, B; Jacob, JS; Khurana, S; Thomas, AS; Varatharajalu, K; Wang, J; Wang, Y; Zhao, D, 2023) |
| "Although oral mesalamine is the first-choice drug for treating mild-to-moderate ulcerative colitis (UC), some patients show symptoms of intolerance, including exacerbation of diarrhea and abdominal pain." | 4.02 | Multicenter survey on mesalamine intolerance in patients with ulcerative colitis. ( Fujiwara, A; Higashi, R; Hiraoka, S; Inokuchi, T; Kato, J; Matsueda, K; Miyaike, J; Moritou, Y; Okada, H; Suzuki, S; Takagi, S; Takahara, M; Toyokawa, T, 2021) |
| " Clinically, pro-drugs such as olsalazine have been associated with dose-dependent diarrhea, which was likely secondary to ileal secretion induced by the azo linkages, in 17% of patients." | 3.73 | Comparative analysis of the in vitro prosecretory effects of balsalazide, sulfasalazine, olsalazine, and mesalamine in rabbit distal ileum. ( Chang, EB; Hanauer, SB; Kles, KA; Musch, MW; Turner, JR; Vavricka, SR, 2005) |
| "Diarrhea was assessed at baseline and end of treatment using the Disease Activity Index (DAI)." | 2.72 | Double-blind pilot study of mesalamine vs. placebo for treatment of chronic diarrhea and nonspecific colitis in immunocompetent HIV patients. ( Fernández-Carbia, A; Marxuach-Cuétara, AM; Ríos-Bedoya, CF; Rodríguez-Orengo, JF; Rodríguez-Torres, M; Salgado-Mercado, R, 2006) |
| "Microscopic colitis is a recently recognized cause of diarrhoea, predominantly affecting older women, but its response to treatment is poorly documented." | 2.67 | Response to treatment of microscopic colitis. ( Fasoli, R; Jewell, DP, 1994) |
| "Microscopic colitis is a common cause of chronic watery diarrhea with a great impact on patient quality of life." | 2.66 | Treatment of microscopic colitis: the role of budesonide and new alternatives for refractory patients. ( Casanova, MJ; Gisbert, JP; Rojo, E, 2020) |
| "Mesalamine is a first-line drug in the treatment of inflammatory bowel diseases, while its intolerance occasionally occurs in clinical practice." | 2.61 | The culprit of mesalamine intolerance: case series and literature review. ( Fu, Y; Hong, F; Quan, R; Xie, C; Yan, W; Zou, K, 2019) |
| "Collagenous colitis is a cause of chronic diarrhea." | 2.55 | Interventions for treating collagenous colitis. ( Chande, N; Kafil, TS; MacDonald, JK; McDonald, JW; Nguyen, TM; Patton, PH, 2017) |
| "Segmental colitis associated with colonic diverticulosis is a new and emerging entity." | 2.48 | Segmental colitis associated with diverticulosis: systematic evaluation of 486 cases with meta-analysis. ( Hoda, KK; Mann, NS, 2012) |
| "Diarrhea is a common clinical feature of inflammatory bowel diseases and may be accompanied by abdominal pain, urgency, and fecal incontinence." | 2.48 | Diarrhea in chronic inflammatory bowel diseases. ( Wenzl, HH, 2012) |
| "Radiation enteritis is a severe problem in patients receiving irradiation of the abdomen or pelvis in the course of cancer treatment." | 2.44 | Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review. ( Böcker, U; Singer, MV; Wenz, F; Zimmerer, T, 2008) |
| "Treatment of ulcerative colitis has changed little in recent years, except for our improved ability to deliver mesalazine to the large bowel via the recent availability of several oral and rectal preparations." | 2.43 | Inflammatory bowel disease. ( Gibson, PR; Iser, J, 2005) |
| "The prednisolone dose was reduced to 7." | 1.51 | Case report of patient with a Cronkhite-Canada syndrome: sustained remission after treatment with corticosteroids and mesalazine. ( Drebber, U; Kaufmann, T; Kütting, F; Mertens, J; Nierhoff, D; Schulte, S; Steffen, HM; Töx, U, 2019) |
| " Dissolution studies of the prepared formulation conducted in simulated colonic fluid clearly demonstrated its superiority over the marketed, delayed release dosage forms of mesalamine." | 1.46 | Role of synbiotics in polysaccharide assisted colon targeted microspheres of mesalamine for the treatment of ulcerative colitis. ( Gulati, M; Kaur, R; Singh, SK, 2017) |
| "Eosinophilic colitis is a rare mostly self-limiting disease affecting middle-aged adults." | 1.40 | Eosinophilic colitis is a sporadic self-limited disease of middle-aged people: a population-based study. ( Alfadda, AA; Shaffer, EA; Storr, MA; Urbanski, SJ, 2014) |
| "Mesalamine suppositories have been used widely for the treatment of distal ulcerative colitis and considered to be safer than systemic administration for its limited systemic absorption." | 1.40 | Ulcerative colitis flair induced by mesalamine suppositories hypersensitivity. ( Ding, H; Hu, J; Hu, XY; Liu, XC; Mei, Q; Xu, JM, 2014) |
| "We present a case of ulcerative colitis in a pediatric liver transplant recipient." | 1.35 | De novo inflammatory bowel disease after pediatric orthotopic liver transplant: a case report. ( Bahador, A; Dehghani, SM; Eshraghian, A; Geramizadeh, B; Kakaei, F; Malek-Hosseini, SA, 2009) |
| "Sulfasalazine is an important therapeutic agent in the management of chronic inflammatory bowel disease (CIBD)." | 1.28 | Sulfasalazine desensitization in children and adolescents with chronic inflammatory bowel disease. ( Tolia, V, 1992) |
| "Collagenous colitis is a rare condition characterized clinically by chronic diarrhea and histologically by a thickened subepithelial collagenous band in colonic biopsies in an endoscopically normal colon." | 1.28 | Familial occurrence of collagenous colitis. A report of two families. ( Blok, P; Dekker, W; Lam, HG; Meuwissen, SG; Seldenrijk, CA; Stel, HV; van Tilburg, AJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (3.90) | 18.7374 |
| 1990's | 15 (19.48) | 18.2507 |
| 2000's | 22 (28.57) | 29.6817 |
| 2010's | 31 (40.26) | 24.3611 |
| 2020's | 6 (7.79) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 1 |
| Wu, YB | 1 |
| Dai, YK | 1 |
| Liu, Q | 1 |
| Ren, YJ | 1 |
| Xu, SJ | 1 |
| Pan, HG | 1 |
| Chen, WJ | 1 |
| Li, RL | 1 |
| Hu, L | 1 |
| Hollander, B | 1 |
| Khurana, S | 1 |
| Jacob, JS | 1 |
| Altan, M | 1 |
| Wang, J | 1 |
| Zhao, D | 1 |
| Varatharajalu, K | 1 |
| Alasadi, M | 1 |
| Thomas, AS | 1 |
| Wang, Y | 1 |
| Dai, C | 1 |
| Jiang, M | 1 |
| Huang, YH | 1 |
| Rojo, E | 1 |
| Casanova, MJ | 1 |
| Gisbert, JP | 1 |
| Hiraoka, S | 2 |
| Fujiwara, A | 1 |
| Toyokawa, T | 1 |
| Higashi, R | 1 |
| Moritou, Y | 1 |
| Takagi, S | 1 |
| Matsueda, K | 1 |
| Suzuki, S | 1 |
| Miyaike, J | 1 |
| Inokuchi, T | 1 |
| Takahara, M | 1 |
| Kato, J | 1 |
| Okada, H | 1 |
| Suzuki, K | 1 |
| Kakuta, Y | 1 |
| Naito, T | 1 |
| Takagawa, T | 1 |
| Hanai, H | 1 |
| Araki, H | 1 |
| Sasaki, Y | 1 |
| Sakuraba, H | 1 |
| Sasaki, M | 1 |
| Hisamatsu, T | 1 |
| Motoya, S | 1 |
| Matsumoto, T | 1 |
| Onodera, M | 1 |
| Ishiguro, Y | 1 |
| Nakase, H | 1 |
| Andoh, A | 1 |
| Shinozaki, M | 1 |
| Fujii, T | 1 |
| Katsurada, T | 1 |
| Kobayashi, T | 2 |
| Fujiya, M | 1 |
| Otsuka, T | 1 |
| Oshima, N | 1 |
| Suzuki, Y | 1 |
| Sato, Y | 1 |
| Hokari, R | 1 |
| Noguchi, M | 1 |
| Ohta, Y | 1 |
| Matsuura, M | 1 |
| Kawai, Y | 1 |
| Tokunaga, K | 1 |
| Nagasaki, M | 1 |
| Kudo, H | 1 |
| Minegishi, N | 1 |
| Okamoto, D | 1 |
| Shimoyama, Y | 1 |
| Moroi, R | 1 |
| Kuroha, M | 1 |
| Shiga, H | 1 |
| Li, D | 1 |
| McGovern, DPB | 1 |
| Kinouchi, Y | 1 |
| Masamune, A | 1 |
| Kafil, TS | 1 |
| Nguyen, TM | 1 |
| Patton, PH | 1 |
| MacDonald, JK | 1 |
| Chande, N | 1 |
| McDonald, JW | 1 |
| Yamauchi, R | 1 |
| Araki, T | 1 |
| Mitsuyama, K | 1 |
| Tokito, T | 1 |
| Ishii, H | 1 |
| Yoshioka, S | 1 |
| Kuwaki, K | 1 |
| Mori, A | 1 |
| Yoshimura, T | 1 |
| Tsuruta, O | 1 |
| Torimura, T | 1 |
| Schulte, S | 2 |
| Kütting, F | 1 |
| Mertens, J | 1 |
| Kaufmann, T | 1 |
| Drebber, U | 1 |
| Nierhoff, D | 1 |
| Töx, U | 1 |
| Steffen, HM | 1 |
| Viazis, N | 1 |
| Pontas, C | 1 |
| Karmiris, K | 1 |
| Dimas, I | 1 |
| Fragaki, M | 1 |
| Paspatis, G | 1 |
| Drygiannakis, I | 1 |
| Koutroubakis, IE | 1 |
| Moschovis, D | 1 |
| Tzouvala, M | 1 |
| Theocharis, G | 1 |
| Tsolias, C | 1 |
| Thomopoulos, K | 1 |
| Zampeli, E | 1 |
| Axiaris, G | 1 |
| Michopoulos, S | 1 |
| Belesiotou, E | 1 |
| Banasa, M | 1 |
| Maraki, S | 1 |
| Kouskoumpekou, F | 1 |
| Apostolopoulos, G | 1 |
| Stamouli, V | 1 |
| Prifti, H | 1 |
| Mantzaris, GJ | 1 |
| Xie, C | 1 |
| Quan, R | 1 |
| Hong, F | 1 |
| Zou, K | 1 |
| Yan, W | 1 |
| Fu, Y | 1 |
| Mann, NS | 1 |
| Hoda, KK | 1 |
| Li, SL | 1 |
| Li, C | 1 |
| Alfadda, AA | 1 |
| Shaffer, EA | 1 |
| Urbanski, SJ | 1 |
| Storr, MA | 1 |
| Ding, H | 1 |
| Liu, XC | 1 |
| Mei, Q | 1 |
| Xu, JM | 1 |
| Hu, XY | 1 |
| Hu, J | 1 |
| Ninan, S | 1 |
| Hamlin, J | 1 |
| Lam, C | 2 |
| Tan, W | 1 |
| Leighton, M | 1 |
| Hastings, M | 1 |
| Lingaya, M | 1 |
| Falcone, Y | 1 |
| Zhou, X | 2 |
| Xu, L | 1 |
| Whorwell, P | 1 |
| Walls, AF | 1 |
| Zaitoun, A | 1 |
| Montgomery, A | 1 |
| Spiller, R | 1 |
| Schorr, M | 1 |
| Vaidya, A | 1 |
| Todd, DJ | 1 |
| Conant, A | 1 |
| Min, T | 1 |
| Ford, AC | 1 |
| Green, EK | 1 |
| Ambrose, LR | 1 |
| Webster, DP | 1 |
| Atkinson, C | 1 |
| Griffiths, P | 1 |
| Murray, CD | 1 |
| Goodman, AL | 1 |
| Mellinger, JL | 1 |
| Pletneva, M | 1 |
| Fontana, RJ | 1 |
| Törnblom, H | 1 |
| Simrén, M | 1 |
| Chang, K | 1 |
| Le Sessions, C | 1 |
| Shillingford, N | 1 |
| Lakhole, A | 1 |
| Ferdman, R | 1 |
| Otani, I | 1 |
| Oka, S | 1 |
| Tanaka, S | 1 |
| Kaur, R | 1 |
| Gulati, M | 1 |
| Singh, SK | 1 |
| Busoni, VB | 1 |
| Lemale, J | 1 |
| Dubern, B | 1 |
| Frangi, F | 1 |
| Bourgeois, P | 1 |
| Orsi, M | 1 |
| Badens, C | 1 |
| Fabre, A | 1 |
| Moum, B | 1 |
| Minor, DR | 1 |
| Chin, K | 1 |
| Kashani-Sabet, M | 1 |
| Dehghani, SM | 1 |
| Eshraghian, A | 1 |
| Bahador, A | 1 |
| Kakaei, F | 1 |
| Geramizadeh, B | 1 |
| Malek-Hosseini, SA | 1 |
| Lawlor, G | 1 |
| Ahmed, A | 1 |
| Moss, AC | 1 |
| Calabrese, C | 1 |
| Gionchetti, P | 2 |
| Liguori, G | 1 |
| Areni, A | 1 |
| Fornarini, GS | 1 |
| Campieri, M | 2 |
| Rizzello, F | 1 |
| Andrews, CN | 1 |
| Griffiths, TA | 1 |
| Kaufman, J | 1 |
| Vergnolle, N | 1 |
| Surette, MG | 1 |
| Rioux, KP | 1 |
| Farup, PG | 1 |
| Denız, K | 1 |
| Coban, G | 1 |
| Ozbakir, O | 1 |
| Denız, E | 1 |
| Strate, LL | 1 |
| Modi, R | 1 |
| Cohen, E | 1 |
| Spiegel, BM | 1 |
| Tuteja, AK | 1 |
| Fang, JC | 1 |
| Al-Suqi, M | 1 |
| Stoddard, GJ | 1 |
| Hale, DC | 1 |
| Braun, S | 1 |
| Budak, K | 1 |
| Vavricka, S | 1 |
| Wenzl, HH | 1 |
| Xue, L | 1 |
| Huang, Z | 1 |
| Chen, W | 1 |
| Leighton, MP | 1 |
| Mehta, S | 1 |
| Spiller, RC | 1 |
| Jani, AL | 1 |
| Hamilos, D | 1 |
| Hartwich, SA | 1 |
| Regueiro, MD | 1 |
| Kles, KA | 1 |
| Vavricka, SR | 1 |
| Turner, JR | 1 |
| Musch, MW | 1 |
| Hanauer, SB | 1 |
| Chang, EB | 1 |
| Gibson, PR | 1 |
| Iser, J | 1 |
| Rodríguez-Torres, M | 1 |
| Rodríguez-Orengo, JF | 1 |
| Ríos-Bedoya, CF | 1 |
| Fernández-Carbia, A | 1 |
| Salgado-Mercado, R | 1 |
| Marxuach-Cuétara, AM | 1 |
| Biancone, L | 1 |
| Blanco, Gdel V | 1 |
| Orlando, A | 1 |
| Annese, V | 1 |
| Papi, C | 1 |
| Sostegni, R | 1 |
| D'Incà, R | 1 |
| Petruzziello, C | 1 |
| Casa, A | 1 |
| Sica, G | 1 |
| Calabrese, E | 1 |
| Pallone, F | 1 |
| de la Iglesia Fanjul, I | 1 |
| de Castro Losa, MR | 1 |
| Izquierdo García, F | 1 |
| Freeman, HJ | 1 |
| Shikuwa, S | 1 |
| Matuoka, Y | 1 |
| Ito, M | 1 |
| Isomoto, H | 1 |
| Kohno, S | 1 |
| Zimmerer, T | 1 |
| Böcker, U | 1 |
| Wenz, F | 1 |
| Singer, MV | 1 |
| Austin, CA | 1 |
| Cann, PA | 1 |
| Jones, TH | 1 |
| Holdsworth, CD | 1 |
| Zins, BJ | 1 |
| Sandborn, WJ | 1 |
| Tremaine, WJ | 1 |
| Fasoli, R | 1 |
| Jewell, DP | 1 |
| Scheurlen, C | 1 |
| Allgayer, H | 1 |
| Kruis, W | 1 |
| Erdmann, E | 1 |
| Sauerbruch, T | 1 |
| Baughan, CA | 1 |
| Canney, PA | 1 |
| Buchanan, RB | 1 |
| Pickering, RM | 1 |
| Veldman, W | 1 |
| van Beek, M | 1 |
| Keuning, JJ | 1 |
| Driessen, WM | 1 |
| Resbeut, M | 1 |
| Marteau, P | 1 |
| Cowen, D | 1 |
| Richaud, P | 1 |
| Bourdin, S | 1 |
| Dubois, JB | 1 |
| Mere, P | 1 |
| N'Guyen, TD | 1 |
| Fine, KD | 1 |
| Sarles, HE | 1 |
| Cryer, B | 1 |
| Robert, FS | 1 |
| Rao, JP | 1 |
| Kang, G | 1 |
| Balasubramanian, KA | 1 |
| Koshi, R | 1 |
| Mathan, MM | 1 |
| Mathan, VI | 1 |
| Wenzl, TG | 1 |
| Kusenbach, G | 1 |
| Skopnik, H | 1 |
| Bonner, GF | 1 |
| Petras, RE | 1 |
| Cheong, DM | 1 |
| Grewal, ID | 1 |
| Breno, S | 1 |
| Ruderman, WB | 1 |
| Goldstein, F | 1 |
| DiMarino, AJ | 1 |
| Abdo, AA | 1 |
| Zetler, PJ | 1 |
| Halparin, LS | 1 |
| Iofel, E | 1 |
| Chawla, A | 1 |
| Daum, F | 1 |
| Markowitz, J | 1 |
| García-Martín, F | 1 |
| Sánchez Heras, M | 1 |
| Sánchez Martínez, L | 1 |
| Rodríguez-Zapata, M | 1 |
| Tolia, V | 1 |
| Butt, JH | 1 |
| Rijk, MC | 1 |
| van Schaik, A | 1 |
| van Tongeren, JH | 1 |
| Kristensen, KS | 1 |
| Høegholm, A | 1 |
| Bohr, L | 1 |
| Friis, S | 1 |
| van Tilburg, AJ | 1 |
| Lam, HG | 1 |
| Seldenrijk, CA | 1 |
| Stel, HV | 1 |
| Blok, P | 1 |
| Dekker, W | 1 |
| Meuwissen, SG | 1 |
| O'Mahony, S | 1 |
| Nawroz, IM | 1 |
| Ferguson, A | 1 |
| Donowitz, M | 1 |
| Järnerot, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Mode of Action of Mesalazine in the Treatment of Diarrhoea-predominant Irritable Bowel Syndrome (IBS-D).[NCT01316718] | Phase 4 | 108 participants (Actual) | Interventional | 2011-03-31 | Completed | ||
| [NCT02003807] | 102 participants (Actual) | Observational | 2013-07-31 | Completed | |||
| Multicentre Controlled, Randomized Clinical Trial to Compare the Efficacy and Safety of Ambulatory Treatment of Mild Acute Diverticulitis Without Antibiotics With the Standard Treatment With Antibiotics[NCT02785549] | Phase 4 | 480 participants (Actual) | Interventional | 2016-11-30 | Completed | ||
| Prevalence of Segmental Colitis Associated With Colic Diverticulosis (SCAD): an Observational Study[NCT04279821] | 50 participants (Anticipated) | Observational | 2020-02-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
15 reviews available for mesalamine and Diarrhea
| Article | Year |
|---|---|
Efficacy and safety of Qingre-Chushi therapies in active ulcerative colitis: A network meta-analysis.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Databases, Factu | 2021 |
Treatment of microscopic colitis: the role of budesonide and new alternatives for refractory patients.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antidiarrheals; Antimetabolites; Azathioprine; Bi | 2020 |
Genetic Background of Mesalamine-induced Fever and Diarrhea in Japanese Patients with Inflammatory Bowel Disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Diarrhea; Genetic Background; Genome-W | 2022 |
Interventions for treating collagenous colitis.
Topics: Bismuth; Boswellia; Budesonide; Cholestyramine Resin; Chronic Disease; Colitis, Collagenous; Diarrhe | 2017 |
The characteristics of nivolumab-induced colitis: an evaluation of three cases and a literature review.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antineoplastic Agents; Coliti | 2018 |
The culprit of mesalamine intolerance: case series and literature review.
Topics: Abdominal Pain; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Diarrhea; Drug Eruptio | 2019 |
Segmental colitis associated with diverticulosis: systematic evaluation of 486 cases with meta-analysis.
Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Biopsy; Colitis; Colonosco | 2012 |
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No | 2012 |
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No | 2012 |
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No | 2012 |
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No | 2012 |
Diarrhea in chronic inflammatory bowel diseases.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidiarrheals; Bacterial Infections | 2012 |
Diagnosis and treatment of ulcerative proctitis.
Topics: Acute Disease; Diagnosis, Differential; Diarrhea; Hemorrhage; Humans; Mesalamine; Proctocolitis; Rec | 2004 |
Inflammatory bowel disease.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colonoscopy; | 2005 |
Medical prevention and treatment of acute and chronic radiation induced enteritis--is there any proven therapy? a short review.
Topics: Abdominal Neoplasms; Acute Disease; Chronic Disease; Combined Modality Therapy; Controlled Clinical | 2008 |
Collagenous and lymphocytic colitis: subject review and therapeutic alternatives.
Topics: Algorithms; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Colitis; | 1995 |
Outpatient management of inflammatory bowel disease. Let's keep it as simple as possible.
Topics: Abdominal Pain; Adrenal Cortex Hormones; Ambulatory Care; Aminosalicylic Acids; Anus Diseases; Diarr | 1992 |
Clinical tolerance of olsalazine.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Diarrhea; Humans; Mesalamine | 1988 |
11 trials available for mesalamine and Diarrhea
| Article | Year |
|---|---|
A mechanistic multicentre, parallel group, randomised placebo-controlled trial of mesalazine for the treatment of IBS with diarrhoea (IBS-D).
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Double-Blind Method; Drug Administra | 2016 |
Clinical course of microscopic colitis in a single-center cohort study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Cholestyramine Resin; Coho | 2011 |
Double-blind placebo-controlled study of mesalamine in post-infective irritable bowel syndrome--a pilot study.
Topics: Abdominal Pain; Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Diarrhea; Dou | 2012 |
Efficacy and mode of action of mesalazine in the treatment of diarrhoea-predominant irritable bowel syndrome (IBS-D): study protocol for a randomised controlled trial.
Topics: Abdominal Pain; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Clinical Protocols; Defecation; Dia | 2013 |
Double-blind pilot study of mesalamine vs. placebo for treatment of chronic diarrhea and nonspecific colitis in immunocompetent HIV patients.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Chronic Disease; Colitis; Colonoscopy; Diarr | 2006 |
Beclomethasone dipropionate versus mesalazine in distal ulcerative colitis: a multicenter, randomized, double-blind study.
Topics: Adult; Aged; Anti-Inflammatory Agents; Beclomethasone; Colitis, Ulcerative; Colonoscopy; Diarrhea; D | 2007 |
Response to treatment of microscopic colitis.
Topics: Aminosalicylic Acids; Colitis; Colon; Diarrhea; Drug Therapy, Combination; Eosinophils; Female; Foll | 1994 |
A randomized trial to assess the efficacy of 5-aminosalicylic acid for the prevention of radiation enteritis.
Topics: Aminosalicylic Acids; Diarrhea; Double-Blind Method; Enteritis; Female; Humans; Male; Mesalamine; Pe | 1993 |
A randomized double blind placebo controlled multicenter study of mesalazine for the prevention of acute radiation enteritis.
Topics: Acute Disease; Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; | 1997 |
Disposition of mesalazine from mesalazine-delivering drugs in patients with inflammatory bowel disease, with and without diarrhoea.
Topics: Adult; Aged; Aminosalicylic Acids; Delayed-Action Preparations; Diarrhea; Drug Carriers; Feces; Fema | 1992 |
Clinical tolerance of olsalazine.
Topics: Aminosalicylic Acids; Clinical Trials as Topic; Colitis, Ulcerative; Diarrhea; Humans; Mesalamine | 1988 |
52 other studies available for mesalamine and Diarrhea
| Article | Year |
|---|---|
Mesalamine and cholestyramine for immune checkpoint inhibitor-mediated diarrhea and colitis.
Topics: Adult; Cholestyramine Resin; Colitis; Diarrhea; Female; Humans; Immune Checkpoint Inhibitors; Immuno | 2023 |
Efficacy of Mesalamine in Irritable Bowel Syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Humans; Irritable Bowel Syndrome; Mesalamine | 2023 |
Multicenter survey on mesalamine intolerance in patients with ulcerative colitis.
Topics: Abdominal Pain; Administration, Oral; Adult; Colitis, Ulcerative; Diarrhea; Disease Progression; Fem | 2021 |
Case report of patient with a Cronkhite-Canada syndrome: sustained remission after treatment with corticosteroids and mesalazine.
Topics: Aged; Alopecia; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Diarrhea; Drug Adm | 2019 |
Prevalence of Clostridium difficile infection among hospitalized inflammatory bowel disease patients in Greece.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Bacteri | 2019 |
Vulvar swelling, plaques, and nodules in a young adult woman.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Constipation; Crohn Disease; Diagnosis, Diff | 2013 |
Eosinophilic colitis is a sporadic self-limited disease of middle-aged people: a population-based study.
Topics: Abdominal Pain; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Colitis; Colon | 2014 |
Ulcerative colitis flair induced by mesalamine suppositories hypersensitivity.
Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colonoscopy; Di | 2014 |
The young patient with acute bloody diarrhoea.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; C-Reactive Pro | 2014 |
Interactive medical case. A man with diarrhea and back pain.
Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents; Back Pain; Colitis, Ulcerative; Colon; Colonoscopy; | 2015 |
Efficacy of mesalazine in IBS.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Female; Humans; Irritable Bowel Syndrome; Male; M | 2016 |
Intractable diarrhoea despite immune reconstitution in an HIV positive man.
Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; CD4 Lymphocyte Count; Cytomeg | 2015 |
New Onset Bloody Diarrhea in a Liver Transplant Recipient. New Onset Bloody Diarrhea in a Liver Transplant Recipient.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Diarrhea; Gastrointestinal Hemorrhage; | 2015 |
In search for a disease-modifying treatment in irritable bowel syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Female; Humans; Irritable Bowel Syndrome; Male; M | 2016 |
Blood and guts: a case of early childhood Crohn's disease.
Topics: Anti-Inflammatory Agents; Biopsy; Child, Preschool; Colonoscopy; Crohn Disease; Diagnosis, Different | 2016 |
Mesalazine-induced enteritis causing refractory diarrhea.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Endoscopy; Enteritis; Female; Humans; Mesal | 2017 |
Role of synbiotics in polysaccharide assisted colon targeted microspheres of mesalamine for the treatment of ulcerative colitis.
Topics: Animals; Body Weight; Colitis, Ulcerative; Colon; Diarrhea; Drug Carriers; Drug Liberation; Feces; F | 2017 |
IBD-Like Features in Syndromic Diarrhea/Trichohepatoenteric Syndrome.
Topics: Anti-Inflammatory Agents; Biological Therapy; Colitis; Colon; Diarrhea; Diarrhea, Infantile; Facies; | 2017 |
Which are the 5-ASA compound side effects and how is it possible to avoid them?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; | 2008 |
Infliximab in the treatment of anti-CTLA4 antibody (ipilimumab) induced immune-related colitis.
Topics: Algorithms; Antibodies, Monoclonal; Antigens, CD; Clinical Trials as Topic; Colitis; CTLA-4 Antigen; | 2009 |
De novo inflammatory bowel disease after pediatric orthotopic liver transplant: a case report.
Topics: Adolescent; Anti-Inflammatory Agents; Biopsy; Chronic Disease; Colitis, Ulcerative; Colon; Colonosco | 2009 |
Once-daily mesalamine granules for ulcerative colitis.
Topics: Abdominal Pain; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Colitis, Ulcerati | 2010 |
Mesalazine (5-aminosalicylic acid) alters faecal bacterial profiles, but not mucosal proteolytic activity in diarrhoea-predominant irritable bowel syndrome.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Bacteria; Diarrhea; DNA, Bacterial; F | 2011 |
Questions about mesalazine and the irritable bowel syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Feces; Female; Humans; Intestinal Mucosa; Irritab | 2011 |
Pseudomembranous collagenous colitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Collagenous; Colonoscopy; Diarrhea; Enterocolitis, | 2012 |
[Probiotics in gastrointestinal diseases].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Combined Modality Therapy; Coop | 2012 |
The possible effects of mesalazine on the intestinal microbiota.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Feces; Female; Humans; Intestinal Mucosa; Irritab | 2012 |
Bloody diarrhea, fever, and pancytopenia in a patient with active ulcerative colitis.
Topics: Antibodies, Antineutrophil Cytoplasmic; Antibodies, Antinuclear; Autoantigens; Autoimmune Diseases; | 2003 |
You're the flight surgeon. Ulcerative colitis.
Topics: Adult; Aerospace Medicine; Anti-Inflammatory Agents, Non-Steroidal; Colic; Colitis, Ulcerative; Diag | 2004 |
You're the flight surgeon. Crohn's disease.
Topics: Abdominal Pain; Adult; Aerospace Medicine; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; D | 2004 |
Comparative analysis of the in vitro prosecretory effects of balsalazide, sulfasalazine, olsalazine, and mesalamine in rabbit distal ileum.
Topics: Aminosalicylic Acids; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Colitis, | 2005 |
[Collagenous colitis. Clinicopathological study of 18 cases].
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; B | 2007 |
Natural history and long-term clinical behavior of segmental colitis associated with diverticulosis (SCAD syndrome).
Topics: Abdominal Pain; Adult; Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Dia | 2008 |
Cobblestone appearance in the colon of a 24-year-old man.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colonic Diseases; Combined Modality Therapy; Diarrhe | 2008 |
Exacerbation of diarrhoea and pain in patients treated with 5-aminosalicylic acid for ulcerative colitis.
Topics: Acute Disease; Adolescent; Adult; Aminosalicylic Acids; Colitis, Ulcerative; Diarrhea; Female; Human | 1984 |
Effect of olsalazine and mesalazine on human ileal and colonic (Na+ + K+)-ATPase. A possible diarrhogenic factor?
Topics: Aminosalicylic Acids; Binding, Competitive; Colon, Sigmoid; Diarrhea; Humans; Ileum; Inflammatory Bo | 1993 |
Regional enteritis complicating malignant lymphoma.
Topics: Adult; Aminosalicylic Acids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti | 1996 |
Diarrhea associated with mesalamine in a patient with chronic nongranulomatous enterocolitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diarrhea; Dinoprostone; Enterocolitis; Fec | 1998 |
Mechanism of purgative effect of magnesium sulphate on mouse colon.
Topics: Animals; Anthracenes; Cathartics; Chloride Channels; Colon; Diarrhea; Disease Models, Animal; Drug I | 1997 |
Salicylate inhibits fimbriae mediated HEp-2 cell adherence of and haemagglutination by enteroaggregative Escherichia coli.
Topics: Adult; Bacterial Adhesion; Bacterial Outer Membrane Proteins; Child; Diarrhea; Epithelial Cells; Ery | 1998 |
Pseudomembranous viral colitis.
Topics: Adenoviridae; Anti-Inflammatory Agents, Non-Steroidal; Antigens, Viral; Child, Preschool; Colonoscop | 2000 |
Short- and long-term follow-up of treatment for lymphocytic and collagenous colitis.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Collagen; Diarrhea | 2000 |
Diarrhea as a side effect of mesalamine treatment for inflammatory bowel disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Female; Humans; Inflammatory Bowel Disease | 2000 |
Familial microscopic colitis.
Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Colitis; Colonoscopy; Consti | 2001 |
Oral balsalazide (Colazal) for ulcerative colitis.
Topics: Abdominal Pain; Administration, Oral; Aminosalicylic Acids; Anti-Ulcer Agents; Colitis, Ulcerative; | 2001 |
Mesalamine intolerance mimics symptoms of active inflammatory bowel disease.
Topics: Abdominal Pain; Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Diarrhea; Female; Humans; Infla | 2002 |
[Nephrogenic diabetes insipidus secondary to chronic interstitial nephritis associated with mesalazine therapy].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diabetes Insipidus, Nephrogenic; Di | 2002 |
Sulfasalazine desensitization in children and adolescents with chronic inflammatory bowel disease.
Topics: Adolescent; Aminosalicylic Acids; Child; Chronic Disease; Desensitization, Immunologic; Diarrhea; Do | 1992 |
Fatal myocarditis associated with mesalazine.
Topics: Adult; Aminosalicylic Acids; Diarrhea; Female; Humans; Mesalamine; Myocarditis | 1990 |
Familial occurrence of collagenous colitis. A report of two families.
Topics: Adult; Aged; Aminosalicylic Acids; Biopsy; Colitis; Collagen; Diarrhea; Female; Humans; Intestinal M | 1990 |
Coeliac disease and collagenous colitis.
Topics: Adult; Aminosalicylic Acids; Celiac Disease; Colitis; Diarrhea; Humans; Jejunum; Male; Mesalamine; R | 1990 |
Arachidonic acid metabolites and their role in inflammatory bowel disease. An update requiring addition of a pathway.
Topics: Aminosalicylic Acids; Arachidonic Acid; Arachidonic Acids; Biological Transport; Bradykinin; Colitis | 1985 |