mesalamine has been researched along with Colonic Neoplasms in 44 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate chemoprevention of colonic polyps with balsalazide, a 5-aminosalicylate prodrug." | 9.14 | Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled study. ( Gum, JR; Hayes, A; Johnson, LK; Kim, YS; McQuaid, KR; Sleisenger, MH; Terdiman, JP; Weinberg, VK, 2009) |
| "To investigate chemoprevention of colonic polyps with balsalazide, a 5-aminosalicylate prodrug." | 5.14 | Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled study. ( Gum, JR; Hayes, A; Johnson, LK; Kim, YS; McQuaid, KR; Sleisenger, MH; Terdiman, JP; Weinberg, VK, 2009) |
| " The in vivo antineoplastic effect of 2-methoxy-5-amino-N-hydroxybenzamide (2-14) was evaluated in a syngenic, CT26-derived xenograft mouse model of CRC and in the azoxymethane/dextran sulfate sodium-induced mouse model of colitis-associated CRC." | 3.76 | Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine. ( Caruso, R; Fantini, MC; Fina, D; Macdonald, TT; Monteleone, G; Pallone, F; Palmieri, G; Pellegrini, R; Sarra, M; Stolfi, C, 2010) |
| " Retrospective correlative studies have suggested that the long-term use of 5-ASA in IBD patients may significantly reduce the risk of development of colorectal cancer." | 2.43 | 5-aminosalicylic acid is an attractive candidate agent for chemoprevention of colon cancer in patients with inflammatory bowel disease. ( Cheng, Y; Desreumaux, P, 2005) |
| " Therapeutic success of mesalazine may be optimized by a combination of high dose and low frequency of dosage to improve compliance." | 2.43 | Indications for 5-aminosalicylate in inflammatory bowel disease: is the body of evidence complete? ( Mulder, CJ; van Bodegraven, AA, 2006) |
| "Butyric acid (BA) is a kind of HDAC inhibitor and thus shows tumor suppression to colon cancer." | 1.62 | A novel dual-prodrug carried by cyclodextrin inclusion complex for the targeting treatment of colon cancer. ( Bai, X; Chen, L; Lin, Y; Liu, Z; Luo, Z; Yang, R; Zhang, Z; Zhong, Z; Zhou, M, 2021) |
| "Patients with primary sclerosing cholangitis (PSC) and ulcerative colitis (UC) are at an increased risk of colorectal neoplasia, but it is unknown if liver transplantation (LT) alters neoplasia progression." | 1.39 | The fate of indefinite and low-grade dysplasia in ulcerative colitis and primary sclerosing cholangitis colitis before and after liver transplantation. ( Eaton, JE; Imam, M; Loftus, EV; Owens, VL; Pardi, DS; Smyrk, TC; Talwalkar, JA, 2013) |
| "5-Aminosalicylic acid lacks the well-known side effects associated with the long-term use of non-steroidal anti-inflammatory drugs." | 1.35 | Inhibition of cell proliferation and invasion in a human colon cancer cell line by 5-aminosalicylic acid. ( Chang, DK; Kim, BJ; Kim, JJ; Kim, MH; Kim, YH; Rhee, JC; Rhee, PL; Son, HJ, 2009) |
| "coli isolates from IBD, colon cancer, and controls was characterized at the cellular and molecular level." | 1.35 | Characterization of epithelial IL-8 response to inflammatory bowel disease mucosal E. coli and its inhibition by mesalamine. ( Campbell, BJ; Corkill, JE; Hart, CA; Rhodes, JM; Roberts, CL; Smith, SL; Subramanian, S; Tam, B; Virji, M; Winstanley, C, 2008) |
| "Human colon cancer cells were treated with vehicle or mesalazine (4 mm or 40 mm)." | 1.34 | Mesalazine downregulates c-Myc in human colon cancer cells. A key to its chemopreventive action? ( Ahluwalia, A; Chai, J; Chu, EC; Tarnawski, AS, 2007) |
| "To investigate the effects of 5-aminosalicylic acid (5-ASA) in combination with nimesulide on the proliferation of HT-29 colon carcinoma cells and its potential mechanisms." | 1.34 | 5-aminosalicylic acid in combination with nimesulide inhibits proliferation of colon carcinoma cells in vitro. ( Fang, HM; Ma, WJ; Mei, Q; Xu, JM, 2007) |
| "The possible association between Crohn's disease and the development of intestinal lymphomas is analyzed." | 1.33 | [MALT lymphoma in a patient with Crohn's disease. A causal or incidental association?]. ( de Dios-Vega, JF; Espigares del Aguila, A; García-Sánchez, MV; Giráldez-Jiménez, MD; Gómez-Camacho, F; Poyato-González, A, 2006) |
| "Interestingly, treatment of ulcerative colitis with mesalazine, which displays few side effects during long-term treatment, is associated with a reduced incidence of colorectal cancer, but its molecular mechanism is not known." | 1.33 | Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity. ( Bos, CL; Diks, SH; Hardwick, JC; Peppelenbosch, MP; Richel, DJ; Walburg, KV, 2006) |
| "An increased incidence of colonic cancer is associated with chronic inflammatory bowel disease." | 1.28 | The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model. ( Crouch, R; Davis, AE; Patterson, F, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (11.36) | 18.2507 |
| 2000's | 22 (50.00) | 29.6817 |
| 2010's | 13 (29.55) | 24.3611 |
| 2020's | 4 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L | 1 |
| Lin, Y | 1 |
| Zhang, Z | 1 |
| Yang, R | 1 |
| Bai, X | 1 |
| Liu, Z | 1 |
| Luo, Z | 1 |
| Zhou, M | 1 |
| Zhong, Z | 1 |
| Bersuder, E | 1 |
| Terciolo, C | 1 |
| Lechevrel, M | 1 |
| Martin, E | 1 |
| Quesnelle, C | 1 |
| Freund, JN | 1 |
| Reimund, JM | 1 |
| Gross, I | 1 |
| Fukunaga, S | 1 |
| Kusaba, Y | 1 |
| Tsuruta, O | 1 |
| Moreno Moraleda, I | 1 |
| Lázaro Sáez, M | 1 |
| Diéguez Castillo, C | 1 |
| Hernández Martínez, Á | 1 |
| Kang, S | 1 |
| Kim, W | 1 |
| Jeong, S | 1 |
| Lee, Y | 1 |
| Nam, J | 1 |
| Lee, S | 1 |
| Jung, Y | 1 |
| Parenti, S | 1 |
| Montorsi, L | 1 |
| Fantini, S | 1 |
| Mammoli, F | 1 |
| Gemelli, C | 1 |
| Atene, CG | 1 |
| Losi, L | 1 |
| Frassineti, C | 1 |
| Calabretta, B | 1 |
| Tagliafico, E | 1 |
| Ferrari, S | 1 |
| Zanocco-Marani, T | 1 |
| Grande, A | 1 |
| Zhang, S | 1 |
| Fu, J | 1 |
| Dogan, B | 1 |
| Scherl, EJ | 1 |
| Simpson, KW | 1 |
| Rousseaux, C | 1 |
| El-Jamal, N | 1 |
| Fumery, M | 1 |
| Dubuquoy, C | 1 |
| Romano, O | 1 |
| Chatelain, D | 1 |
| Langlois, A | 1 |
| Bertin, B | 1 |
| Buob, D | 1 |
| Colombel, JF | 1 |
| Cortot, A | 1 |
| Desreumaux, P | 2 |
| Dubuquoy, L | 1 |
| Managlia, E | 1 |
| Katzman, RB | 1 |
| Brown, JB | 1 |
| Barrett, TA | 1 |
| Sharma, R | 1 |
| Rawal, RK | 1 |
| Gaba, T | 1 |
| Singla, N | 1 |
| Malhotra, M | 1 |
| Matharoo, S | 1 |
| Bhardwaj, TR | 1 |
| Eaton, JE | 1 |
| Smyrk, TC | 1 |
| Imam, M | 1 |
| Pardi, DS | 1 |
| Loftus, EV | 1 |
| Owens, VL | 1 |
| Talwalkar, JA | 1 |
| MacFie, TS | 1 |
| Poulsom, R | 1 |
| Parker, A | 1 |
| Warnes, G | 1 |
| Boitsova, T | 1 |
| Nijhuis, A | 1 |
| Suraweera, N | 1 |
| Poehlmann, A | 1 |
| Szary, J | 1 |
| Feakins, R | 1 |
| Jeffery, R | 1 |
| Harper, RW | 1 |
| Jubb, AM | 1 |
| Lindsay, JO | 1 |
| Silver, A | 1 |
| Jegadeesan, R | 1 |
| Navaneethan, U | 1 |
| Gutierrez, NG | 1 |
| Venkatesh, PG | 1 |
| Hammel, JP | 1 |
| Sanaka, MR | 1 |
| Shen, B | 1 |
| Schwab, M | 1 |
| Reynders, V | 1 |
| Loitsch, S | 1 |
| Shastri, YM | 1 |
| Steinhilber, D | 1 |
| Schröder, O | 1 |
| Stein, J | 1 |
| Kim, YH | 1 |
| Kim, MH | 1 |
| Kim, BJ | 1 |
| Kim, JJ | 1 |
| Chang, DK | 1 |
| Son, HJ | 1 |
| Rhee, PL | 1 |
| Rhee, JC | 1 |
| Das, KK | 1 |
| Bajpai, M | 1 |
| Kong, Y | 1 |
| Liu, J | 1 |
| Geng, X | 1 |
| Das, KM | 1 |
| Stolfi, C | 3 |
| Sarra, M | 3 |
| Caruso, R | 3 |
| Fantini, MC | 3 |
| Fina, D | 3 |
| Pellegrini, R | 1 |
| Palmieri, G | 1 |
| Macdonald, TT | 1 |
| Pallone, F | 3 |
| Monteleone, G | 3 |
| Terdiman, JP | 1 |
| Johnson, LK | 2 |
| Kim, YS | 2 |
| Sleisenger, MH | 2 |
| Gum, JR | 1 |
| Hayes, A | 1 |
| Weinberg, VK | 1 |
| McQuaid, KR | 1 |
| Da-Silva, N | 1 |
| Arasaradnam, R | 1 |
| Getliffe, K | 1 |
| Sung, E | 1 |
| Oo, Y | 1 |
| Nwokolo, C | 1 |
| Qualtrough, D | 1 |
| Smallwood, K | 1 |
| Littlejohns, D | 1 |
| Pignatelli, M | 1 |
| Khare, V | 1 |
| Lyakhovich, A | 1 |
| Dammann, K | 1 |
| Lang, M | 1 |
| Borgmann, M | 1 |
| Tichy, B | 1 |
| Pospisilova, S | 1 |
| Luciani, G | 1 |
| Campregher, C | 1 |
| Evstatiev, R | 1 |
| Pflueger, M | 1 |
| Hundsberger, H | 1 |
| Gasche, C | 1 |
| Reinacher-Schick, A | 1 |
| Schoeneck, A | 1 |
| Graeven, U | 1 |
| Schwarte-Waldhoff, I | 1 |
| Schmiegel, W | 1 |
| Narisawa, T | 2 |
| Fukaura, Y | 2 |
| Bernstein, CN | 1 |
| Cheng, Y | 1 |
| García-Sánchez, MV | 1 |
| Poyato-González, A | 1 |
| Giráldez-Jiménez, MD | 1 |
| Gómez-Camacho, F | 1 |
| Espigares del Aguila, A | 1 |
| de Dios-Vega, JF | 1 |
| Bos, CL | 1 |
| Diks, SH | 1 |
| Hardwick, JC | 1 |
| Walburg, KV | 1 |
| Peppelenbosch, MP | 1 |
| Richel, DJ | 1 |
| Fallingborg, JF | 1 |
| van Bodegraven, AA | 1 |
| Mulder, CJ | 1 |
| Chu, EC | 1 |
| Chai, J | 1 |
| Ahluwalia, A | 1 |
| Tarnawski, AS | 1 |
| Fang, HM | 1 |
| Mei, Q | 1 |
| Xu, JM | 1 |
| Ma, WJ | 1 |
| Subramanian, S | 1 |
| Rhodes, JM | 1 |
| Hart, CA | 1 |
| Tam, B | 1 |
| Roberts, CL | 1 |
| Smith, SL | 1 |
| Corkill, JE | 1 |
| Winstanley, C | 1 |
| Virji, M | 1 |
| Campbell, BJ | 1 |
| Caprioli, F | 2 |
| Rizzo, A | 2 |
| Hallak, A | 1 |
| Baratz, M | 1 |
| Santo, M | 1 |
| Halpern, Z | 1 |
| Rabau, M | 1 |
| Werbin, N | 1 |
| Gilat, T | 1 |
| Schölmerich, J | 1 |
| Fornaciari, G | 1 |
| Maccari, S | 1 |
| Borgatti, PP | 1 |
| Rustichelli, R | 1 |
| Amelio, N | 1 |
| Lattuada, I | 1 |
| Plancher, AC | 1 |
| MacGregor, DJ | 1 |
| Allgayer, H | 1 |
| Tillmann, T | 1 |
| Hombach, A | 1 |
| Kruis, W | 1 |
| Pohl, C | 1 |
| Takeba, N | 1 |
| Nakai, K | 1 |
| Davis, AE | 1 |
| Patterson, F | 1 |
| Crouch, R | 1 |
| Pullman, WE | 1 |
| Doe, WF | 1 |
5 reviews available for mesalamine and Colonic Neoplasms
| Article | Year |
|---|---|
Ulcerative colitis with low-grade dysplasia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cell Transformation, Neoplastic; Colectomy; Colitis, | 2004 |
5-aminosalicylic acid is an attractive candidate agent for chemoprevention of colon cancer in patients with inflammatory bowel disease.
Topics: Colonic Neoplasms; Humans; Inflammatory Bowel Diseases; Mesalamine | 2005 |
[Does 5-ASA prevent development of colon cancer in ulcerative colitis?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colonic Neoplasms; Humans; Mesalamine; | 2006 |
Indications for 5-aminosalicylate in inflammatory bowel disease: is the body of evidence complete?
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Colonic Neoplasms; Humans; Inflammatory Bow | 2006 |
[Treatment and recurrence prevention ulcerative colitis].
Topics: Acute Disease; Adrenal Cortex Hormones; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroida | 1995 |
1 trial available for mesalamine and Colonic Neoplasms
| Article | Year |
|---|---|
Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled study.
Topics: Adenoma; Aged; Apoptosis; Colon, Sigmoid; Colonic Neoplasms; Colonic Polyps; Double-Blind Method; Ga | 2009 |
38 other studies available for mesalamine and Colonic Neoplasms
| Article | Year |
|---|---|
A novel dual-prodrug carried by cyclodextrin inclusion complex for the targeting treatment of colon cancer.
Topics: Animals; Antineoplastic Agents; Butyric Acid; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasm | 2021 |
Mesalazine initiates an anti-oncogenic β-catenin / MUCDHL negative feed-back loop in colon cancer cells by cell-specific mechanisms.
Topics: beta Catenin; Cadherin Related Proteins; Cadherins; Colonic Neoplasms; Colorectal Neoplasms; Humans; | 2022 |
Use of Endocytoscopy for Ulcerative Colitis Surveillance: A Case Study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Colitis, Ulcerative; Colonic Neoplasms; Colo | 2020 |
Inflammatory bowel disease and inherited colorectal cancer: Is there a genetic link?
Topics: Adenocarcinoma; Adult; Age of Onset; Anti-Inflammatory Agents; Azathioprine; Breast Neoplasms; Colit | 2021 |
Oxidized 5-aminosalicylic acid activates Nrf2-HO-1 pathway by covalently binding to Keap1: Implication in anti-inflammatory actions of 5-aminosalicylic acid.
Topics: Animals; Anti-Inflammatory Agents; Colonic Neoplasms; HCT116 Cells; Heme Oxygenase-1; Humans; Hypoch | 2017 |
KLF4 Mediates the Effect of 5-ASA on the β-Catenin Pathway in Colon Cancer Cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Caco-2 Cells; Cadherin Related Proteins; Cadh | 2018 |
5-Aminosalicylic acid downregulates the growth and virulence of Escherichia coli associated with IBD and colorectal cancer, and upregulates host anti-inflammatory activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Colonic Neoplasms; Comet Assay; Dose-Re | 2018 |
The 5-aminosalicylic acid antineoplastic effect in the intestine is mediated by PPARγ.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Azoxymethane; Blotting, Western; Cell P | 2013 |
Antioxidant properties of mesalamine in colitis inhibit phosphoinositide 3-kinase signaling in progenitor cells.
Topics: Adolescent; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; beta Catenin; Blotting, | 2013 |
Design, synthesis and ex vivo evaluation of colon-specific azo based prodrugs of anticancer agents.
Topics: Animals; Antineoplastic Agents; Azo Compounds; Cell Line, Tumor; Colon; Colonic Neoplasms; Drug Desi | 2013 |
The fate of indefinite and low-grade dysplasia in ulcerative colitis and primary sclerosing cholangitis colitis before and after liver transplantation.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cholangitis, Sclerosing; Colitis, Ulcerative; | 2013 |
DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.
Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cells, Cultured; Colitis, Ulcer | 2014 |
Pattern of Inflammation on Surveillance Colonoscopy Does Not Predict Development of Colitis-associated Neoplasia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Colitis, Ulcerative; Colonic N | 2016 |
PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells.
Topics: Apoptosis; Caco-2 Cells; Caspase 3; Caspase 8; Cell Cycle; Cell Growth Processes; Colonic Neoplasms; | 2008 |
Inhibition of cell proliferation and invasion in a human colon cancer cell line by 5-aminosalicylic acid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Colonic Neoplasms; Down-Regulation; Gen | 2009 |
Ulcerative colitis.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Causality; Colitis, Ulcerative; C | 2008 |
Mesalamine suppresses the expression of TC22, a novel tropomyosin isoform associated with colonic neoplasia.
Topics: Antibodies, Monoclonal; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, | 2009 |
Inhibition of colon carcinogenesis by 2-methoxy-5-amino-N-hydroxybenzamide, a novel derivative of mesalamine.
Topics: Aminosalicylic Acids; Animals; Anticarcinogenic Agents; Azoxymethane; Benzamides; Carcinogens; Cell | 2010 |
Altered mRNA expression of telomere binding proteins (TPP1, POT1, RAP1, TRF1 and TRF2) in ulcerative colitis and Crohn's disease.
Topics: Azathioprine; Biomarkers, Tumor; Chromosomal Instability; Colitis, Ulcerative; Colon; Colonic Neopla | 2010 |
The actin-bundling protein fascin is overexpressed in inflammatory bowel disease and may be important in tissue repair.
Topics: Actins; Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Butyrates; Carrier Proteins; Cell L | 2011 |
Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; beta Catenin; Cadherins; | 2013 |
Mesalazine causes a mitotic arrest and induces caspase-dependent apoptosis in colon carcinoma cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Caspases; Cell Division; Colonic Neoplasms; G2 Phase; HT29 | 2003 |
Prevention by intrarectal 5-aminosalicylic acid of N-methylnitrosourea-induced colon cancer in F344 rats.
Topics: Administration, Rectal; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Transformation, Neopl | 2003 |
[Colon carcinoma. Outlooks of prevention useful].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colonic Neoplasms; Diet; Humans; Mesal | 2004 |
[MALT lymphoma in a patient with Crohn's disease. A causal or incidental association?].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Colonic Neoplasms; Crohn Disease; Female; Humans; Lym | 2006 |
Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity.
Topics: Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Cell Line, Tumor; Colitis, Ulcerative; Coloni | 2006 |
Mesalazine downregulates c-Myc in human colon cancer cells. A key to its chemopreventive action?
Topics: Annexin A5; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Colitis, Ulcerati | 2007 |
5-aminosalicylic acid in combination with nimesulide inhibits proliferation of colon carcinoma cells in vitro.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Proliferation; Colonic Neop | 2007 |
Characterization of epithelial IL-8 response to inflammatory bowel disease mucosal E. coli and its inhibition by mesalamine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Cells, Cultured; Colonic Neoplasms; E | 2008 |
Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid.
Topics: Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinop | 2008 |
Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phase.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; cdc25 Phosphatases; Cell Prolif | 2008 |
Ileitis after colectomy for ulcerative colitis or carcinoma.
Topics: Adult; Aged; Aminosalicylic Acids; Azathioprine; Colectomy; Colitis, Ulcerative; Colonic Neoplasms; | 1994 |
Nephrotic syndrome from 5-ASA for ulcerative colitis? Complicated by carcinoma of the colon and sclerosing cholangitis.
Topics: Adult; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Cholangitis, Sclerosing; Colit | 1997 |
Chemoprevention of colon cancer carcinogenesis by balsalazide: inhibition of azoxymethane-induced aberrant crypt formation in the rat colon and intestinal tumor formation in the B6-Min/+ mouse.
Topics: Aminosalicylic Acids; Animals; Anti-Ulcer Agents; Anticarcinogenic Agents; Azoxymethane; Cell Divisi | 2000 |
[Aminosalicylates and aspirin for colonic cancer: from anti-inflammatory to antineoplastic drugs?].
Topics: Antineoplastic Agents; Apoptosis; Aspirin; Colonic Neoplasms; DNA Damage; Humans; Mesalamine; Treatm | 2000 |
Chemoprevention of N-methylnitrosourea-induced colon carcinogenesis by ursodeoxycholic acid-5-aminosalicylic acid conjugate in F344 rats.
Topics: Animals; Anticarcinogenic Agents; Bile Acids and Salts; Colonic Neoplasms; Female; Mesalamine; Methy | 2002 |
The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model.
Topics: Adenocarcinoma; Aminosalicylic Acids; Animals; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazin | 1992 |
IL-2 production by intestinal lamina propria cells in normal inflamed and cancer-bearing colons.
Topics: Aminosalicylic Acids; Colonic Neoplasms; Cyclosporine; Humans; Hydrocortisone; Inflammatory Bowel Di | 1992 |