mesalamine has been researched along with Colonic Diverticulosis in 27 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mesalazine does not prevent the recurrence of diverticulitis in patients with SUDD." | 2.58 | Effect of mesalazine on recurrence of diverticulitis in patients with symptomatic uncomplicated diverticular disease: a meta-analysis with trial sequential analysis of randomized controlled trials. ( Ali, B; Hajibandeh, S; Khan, RMA, 2018) |
| "Segmental colitis associated with colonic diverticulosis is a new and emerging entity." | 2.48 | Segmental colitis associated with diverticulosis: systematic evaluation of 486 cases with meta-analysis. ( Hoda, KK; Mann, NS, 2012) |
| "Colonic diverticulosis is an increasingly common condition in Western industrialized countries." | 1.43 | Treatment of Diverticular Disease With Aminosalicylates: The Evidence. ( Barbara, G; Barbaro, MR; Bellacosa, L; Cremon, C; Stanghellini, V, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (40.74) | 29.6817 |
| 2010's | 16 (59.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, RMA | 1 |
| Ali, B | 1 |
| Hajibandeh, S | 2 |
| Alamo, RZ | 1 |
| Quigley, EMM | 1 |
| Kruis, W | 1 |
| Meier, E | 1 |
| Schumacher, M | 1 |
| Mickisch, O | 1 |
| Greinwald, R | 1 |
| Mueller, R | 1 |
| Mann, NS | 1 |
| Hoda, KK | 1 |
| Tursi, A | 12 |
| Di Mario, F | 6 |
| Brandimarte, G | 9 |
| Elisei, W | 9 |
| Picchio, M | 5 |
| Loperfido, S | 1 |
| Dal Bo', N | 1 |
| Ferrara, F | 1 |
| Marcello, R | 1 |
| Heras Salvat, H | 1 |
| Scarpignato, C | 4 |
| Kruse, E | 1 |
| Leifeld, L | 1 |
| Mosadeghi, S | 1 |
| Bhuket, T | 1 |
| Stollman, N | 1 |
| Gargallo Puyuelo, CJ | 1 |
| Sopeña, F | 1 |
| Lanas Arbeloa, A | 1 |
| Malfertheiner, P | 1 |
| Barbara, G | 1 |
| Cremon, C | 1 |
| Barbaro, MR | 1 |
| Bellacosa, L | 1 |
| Stanghellini, V | 1 |
| Giorgetti, GM | 4 |
| Inchingolo, CD | 3 |
| Aiello, F | 3 |
| Freeman, HJ | 1 |
| Humes, D | 1 |
| Simpson, J | 2 |
| Spiller, RC | 1 |
| Giorgetti, G | 1 |
| Nenna, R | 1 |
| Giorgio, F | 1 |
| Ierardi, E | 1 |
| Rinas, U | 1 |
| Adamek, HE | 1 |
| Spiller, R | 1 |
| Comparato, G | 3 |
| Fanigliulo, L | 3 |
| Aragona, G | 3 |
| Cavallaro, LG | 3 |
| Cavestro, GM | 3 |
| Franzé, A | 3 |
| Iori, V | 1 |
| Maino, M | 1 |
| Mazzocchi, G | 1 |
| Muzzetto, P | 1 |
| Colla, G | 1 |
| Sianesi, M | 2 |
| Mario, FD | 1 |
| Leandro, G | 1 |
| Pilotto, A | 1 |
| Nervi, G | 1 |
| Soliani, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-blind, Randomised, Placebo-controlled, Parallel-group, Multi-centre Phase III Clinical Study on the Efficacy and Tolerability of Mesalazine Pellets vs. Placebo in Diverticular Disease[NCT01627262] | Phase 2 | 123 participants (Actual) | Interventional | 2002-05-31 | Completed | ||
| Multicentre Controlled, Randomized Clinical Trial to Compare the Efficacy and Safety of Ambulatory Treatment of Mild Acute Diverticulitis Without Antibiotics With the Standard Treatment With Antibiotics[NCT02785549] | Phase 4 | 480 participants (Actual) | Interventional | 2016-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for mesalamine and Colonic Diverticulosis
| Article | Year |
|---|---|
Effect of mesalazine on recurrence of diverticulitis in patients with symptomatic uncomplicated diverticular disease: a meta-analysis with trial sequential analysis of randomized controlled trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Diverticulosis, Colonic; Humans; M | 2018 |
Irritable bowel syndrome and colonic diverticular disease: overlapping symptoms and overlapping therapeutic approaches.
Topics: Abdominal Pain; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Diverticulosis, Co | 2019 |
Segmental colitis associated with diverticulosis: systematic evaluation of 486 cases with meta-analysis.
Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Biopsy; Colitis; Colonosco | 2012 |
[Prevention and conservative therapy of diverticular disease].
Topics: Anti-Bacterial Agents; Dietary Fiber; Diverticulitis, Colonic; Diverticulosis, Colonic; Evidence-Bas | 2014 |
New physiopathological and therapeutic approaches to diverticular disease: an update.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Colon; Dietary Fiber; Diver | 2014 |
Diverticular disease: evolving concepts in classification, presentation, and management.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colonoscopy; Dietary Fiber; | 2015 |
Colonic diverticular disease. Treatment and prevention.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Contraind | 2015 |
Mesalazine for the Treatment of Symptomatic Uncomplicated Diverticular Disease of the Colon and for Primary Prevention of Diverticulitis: A Systematic Review of Randomized Clinical Trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Diverticulosis, Colonic; Female; H | 2016 |
Colonic diverticular disease.
Topics: Acute Disease; Diverticulitis; Diverticulitis, Colonic; Diverticulosis, Colonic; Diverticulum; Human | 2007 |
[Diverticulosis/diverticulitis? What are conservative therapy possibilities?].
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non- | 2006 |
Colonic diverticular disease.
Topics: Acute Disease; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Dietary Fiber; Divert | 2005 |
Use of mesalazine in diverticular disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Disease Progression; Diverticulitis, Colonic; Di | 2006 |
4 trials available for mesalamine and Colonic Diverticulosis
| Article | Year |
|---|---|
Randomised clinical trial: mesalazine (Salofalk granules) for uncomplicated diverticular disease of the colon--a placebo-controlled study.
Topics: Abdominal Pain; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diverticulosis, Co | 2013 |
Mesalazine and/or Lactobacillus casei in preventing recurrence of symptomatic uncomplicated diverticular disease of the colon: a prospective, randomized, open-label study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diverticulosis, Colonic; Fe | 2006 |
Prevention of complications and symptomatic recurrences in diverticular disease with mesalazine: a 12-month follow-up.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Barium Sulfate; Colonoscopy | 2007 |
Quality of life in uncomplicated symptomatic diverticular disease: is it another good reason for treatment?
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Diverticulo | 2007 |
11 other studies available for mesalamine and Colonic Diverticulosis
| Article | Year |
|---|---|
Mesalazine in treating diverticular disease of the colon.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticulosis, Colonic; Female; Humans; Male; Mesalamine | 2013 |
Intermittent versus every-day mesalazine therapy in preventing complications of diverticular disease: a long-term follow-up study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Di | 2013 |
Prognostic Role of the Endoscopic Classification "DICA".
Topics: Abdominal Pain; Aged; Anti-Inflammatory Agents, Non-Steroidal; C-Reactive Protein; Colon; Colonoscop | 2016 |
Treatment of Diverticular Disease With Aminosalicylates: The Evidence.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Diverticulosis, Colonic; Humans; Mesa | 2016 |
Current Management of Patients With Diverticulosis and Diverticular Disease: A Survey From the 2nd International Symposium on Diverticular Disease.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Colonoscopy; Congresses as Topic; Di | 2016 |
Faecal calprotectin in colonic diverticular disease: a case-control study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Colonoscopy; Diverticulosis, Colonic; | 2009 |
Segmental colitis associated with diverticulosis syndrome.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis; Diagnosis, Differential; Disease Progression; Dive | 2008 |
Role of fecal calprotectin in the diagnosis and treatment of segmental colitis associated with diverticulosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Case-Control Studies; Colitis, Ulcerative | 2011 |
Mucosal expression of basic fibroblastic growth factor, Syndecan 1 and tumor necrosis factor-alpha in diverticular disease of the colon: a case-control study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Case | 2012 |
Diverticular disease of the colon.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Diverticulosis, Colonic; Humans; M | 2004 |
Effect of mesalazine on epithelial cell proliferation in colonic diverticular disease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Needle; Case-Control Studies; Cell Proliferat | 2008 |