mesalamine has been researched along with Colonic Diverticulitis in 52 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Mesalazine is as effective as rifaximin (higher dosage schedule) for diminishing some symptoms, but it appears to be better than rifaximin for improving the global score in those patients." | 2.71 | Efficacy of mesalazine in the treatment of symptomatic diverticular disease. ( Aragona, G; Cavallaro, LG; Cavestro, GM; Comparato, G; Di Mario, F; Fanigliulo, L; Franzé, A; Gnocchi, A; Iori, V; Leandro, G; Maino, M; Mazzocchi, G; Moussa, AM, 2005) |
| "Mesalazine does not prevent the recurrence of diverticulitis in patients with SUDD." | 2.58 | Effect of mesalazine on recurrence of diverticulitis in patients with symptomatic uncomplicated diverticular disease: a meta-analysis with trial sequential analysis of randomized controlled trials. ( Ali, B; Hajibandeh, S; Khan, RMA, 2018) |
| " Only randomized clinical trials (RCTs) (irrespective of language, blinding, or publication status), which compared mesalazine, irrespective of the dosage assumption, with placebo in SUDD were evaluated." | 2.58 | Mesalazine to treat symptomatic uncomplicated diverticular disease and to prevent acute diverticulitis occurrence. A systematic review with meta-analysis of randomized, placebo-controlled trials. ( Elisei, W; Picchio, M; Tursi, A, 2018) |
| "The incidence of diverticulosis and diverticular disease of the colon, including diverticulitis, is increasing worldwide, and becoming a significant burden on national health systems." | 2.52 | Review article: the pathophysiology and medical management of diverticulosis and diverticular disease of the colon. ( Danese, S; Papa, A; Tursi, A, 2015) |
| "Balsalazide is a 5-amino salicylic acid prodrug well-tolerated and effective in treating acute ulcerative colitis." | 2.44 | Balsalazide plus high-potency probiotic preparation (VSL[sharp]3) in the treatment of acute mild-to-moderate ulcerative colitis and uncomplicated diverticulitis of the colon. ( Tursi, A, 2008) |
| "Symptomatic recurrence of diverticulitis occurred in 3 patients in group A, while 13 patients showed recurrence of diverticulitis in group B (p < 0." | 1.31 | Long-term treatment with mesalazine and rifaximin versus rifaximin alone for patients with recurrent attacks of acute diverticulitis of colon. ( Brandimarte, G; Daffinà, R; Tursi, A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 22 (42.31) | 29.6817 |
| 2010's | 28 (53.85) | 24.3611 |
| 2020's | 2 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Balk, EM | 1 |
| Adam, GP | 1 |
| Cao, W | 1 |
| Mehta, S | 1 |
| Shah, N | 1 |
| Hall, J | 1 |
| Hardiman, K | 1 |
| Lee, S | 1 |
| Lightner, A | 1 |
| Stocchi, L | 1 |
| Paquette, IM | 1 |
| Steele, SR | 1 |
| Feingold, DL | 1 |
| Kruis, W | 2 |
| Greinwald, R | 1 |
| Gracie, DJ | 1 |
| Ford, AC | 1 |
| Carter, F | 1 |
| Alsayb, M | 1 |
| Marshall, JK | 1 |
| Yuan, Y | 1 |
| Khan, RMA | 1 |
| Ali, B | 2 |
| Hajibandeh, S | 2 |
| Picchio, M | 6 |
| Elisei, W | 7 |
| Tursi, A | 18 |
| Giorgetti, GM | 3 |
| Inchingolo, CD | 2 |
| Nenna, R | 2 |
| Maiorano, M | 1 |
| Penna, A | 1 |
| Lecca, PG | 1 |
| Brandimarte, G | 7 |
| Di Mario, F | 6 |
| Loperfido, S | 1 |
| Dal Bo', N | 1 |
| Ferrara, F | 1 |
| Marcello, R | 1 |
| Heras Salvat, H | 1 |
| Scarpignato, C | 3 |
| Kruse, E | 1 |
| Leifeld, L | 2 |
| Gargallo Puyuelo, CJ | 1 |
| Sopeña, F | 1 |
| Lanas Arbeloa, A | 1 |
| Papa, A | 1 |
| Danese, S | 1 |
| Jaung, R | 1 |
| Robertson, J | 1 |
| Vather, R | 1 |
| Rowbotham, D | 1 |
| Bissett, IP | 1 |
| Scaioli, E | 1 |
| Colecchia, A | 1 |
| Marasco, G | 1 |
| Schiumerini, R | 1 |
| Festi, D | 1 |
| Khan, MA | 1 |
| Lee, WM | 1 |
| Howden, CW | 1 |
| Malfertheiner, P | 1 |
| Dai, C | 1 |
| Jiang, M | 1 |
| Sun, MJ | 1 |
| Fan, YC | 1 |
| Peery, AF | 1 |
| Humes, D | 1 |
| Simpson, J | 4 |
| Spiller, RC | 1 |
| Papagrigoriadis, S | 1 |
| Gatta, L | 2 |
| Vakil, N | 1 |
| Vaira, D | 2 |
| Pilotto, A | 2 |
| Curlo, M | 2 |
| Comparato, G | 4 |
| Leandro, G | 2 |
| Ferro, U | 1 |
| Lera, M | 2 |
| Milletti, S | 1 |
| Ahn, SB | 1 |
| Han, DS | 1 |
| Park, HS | 1 |
| Kim, TY | 1 |
| Eun, CS | 1 |
| Jeon, YC | 1 |
| Sohn, JH | 1 |
| Lucarini, P | 1 |
| Enkleda, K | 1 |
| Franzé, A | 4 |
| Bassotti, G | 1 |
| Villanacci, V | 1 |
| Giorgetti, G | 1 |
| Aiello, F | 2 |
| Maconi, G | 1 |
| Barbara, G | 1 |
| Bosetti, C | 1 |
| Cuomo, R | 1 |
| Annibale, B | 1 |
| Gross, V | 1 |
| Giorgio, F | 1 |
| Ierardi, E | 1 |
| Strate, LL | 1 |
| Modi, R | 1 |
| Cohen, E | 1 |
| Spiegel, BM | 1 |
| Daffinà, R | 1 |
| Spiller, R | 3 |
| Aragona, G | 3 |
| Fanigliulo, L | 3 |
| Cavallaro, LG | 3 |
| Cavestro, GM | 3 |
| Iori, V | 2 |
| Maino, M | 2 |
| Moussa, AM | 1 |
| Gnocchi, A | 1 |
| Mazzocchi, G | 2 |
| Ierfone, N | 1 |
| Di Fulvio, A | 1 |
| Pontone, S | 1 |
| Terzakis, P | 1 |
| Martino, G | 1 |
| Pontone, P | 1 |
| Floch, MH | 1 |
| White, JA | 1 |
| Cohen, HD | 1 |
| Das, KM | 1 |
| Hoffmann, R | 1 |
| Muzzetto, P | 1 |
| Colla, G | 1 |
| Sianesi, M | 1 |
| Mario, FD | 1 |
| Freeman, HJ | 1 |
| Imperiali, G | 1 |
| Meucci, G | 1 |
| Alvisi, C | 1 |
| Fasoli, R | 1 |
| Ferrara, A | 1 |
| Girelli, CM | 1 |
| Rocca, F | 1 |
| Saibeni, S | 1 |
| Minoli, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-blind, Randomized, Placebo-controlled, Parallel Group, Multi-centre Phase III Clinical Study on the Efficacy and Tolerability of Mesalazine Granules vs. Placebo for the Prevention of Recurrence of Diverticulitis[NCT00695643] | Phase 3 | 345 participants (Actual) | Interventional | 2008-01-31 | Terminated | ||
| Double-blind, Dose-response, Randomised, Placebo-controlled, Parallel Group, Multi-centre Phase III Clinical Study on the Efficacy and Tolerability of Mesalazine Granules vs. Placebo for the Prevention of Recurrence of Diverticulitis[NCT01038739] | Phase 3 | 330 participants (Actual) | Interventional | 2010-01-31 | Terminated (stopped due to Stopped due to futility.) | ||
| Multicentre Controlled, Randomized Clinical Trial to Compare the Efficacy and Safety of Ambulatory Treatment of Mild Acute Diverticulitis Without Antibiotics With the Standard Treatment With Antibiotics[NCT02785549] | Phase 4 | 480 participants (Actual) | Interventional | 2016-11-30 | Completed | ||
| Diverticular Disease Register (REMAD)[NCT03325829] | 1,217 participants (Actual) | Observational [Patient Registry] | 2015-04-30 | Active, not recruiting | |||
| [NCT02003807] | 102 participants (Actual) | Observational | 2013-07-31 | Completed | |||
| Prevalence of Segmental Colitis Associated With Colic Diverticulosis (SCAD): an Observational Study[NCT04279821] | 50 participants (Anticipated) | Observational | 2020-02-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
30 reviews available for mesalamine and Colonic Diverticulitis
| Article | Year |
|---|---|
Evaluation and Management After Acute Left-Sided Colonic Diverticulitis : A Systematic Review.
Topics: Colonoscopy; Diverticulitis; Diverticulitis, Colonic; Humans; Mesalamine; United States | 2022 |
Mesalamine (5-ASA) for the prevention of recurrent diverticulitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Humans; Mesalamine; Randomized Con | 2017 |
Effect of mesalazine on recurrence of diverticulitis in patients with symptomatic uncomplicated diverticular disease: a meta-analysis with trial sequential analysis of randomized controlled trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Diverticulosis, Colonic; Humans; M | 2018 |
Mesalazine to treat symptomatic uncomplicated diverticular disease and to prevent acute diverticulitis occurrence. A systematic review with meta-analysis of randomized, placebo-controlled trials.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diverticulit | 2018 |
[Prevention and conservative therapy of diverticular disease].
Topics: Anti-Bacterial Agents; Dietary Fiber; Diverticulitis, Colonic; Diverticulosis, Colonic; Evidence-Bas | 2014 |
Colonic diverticular disease. Treatment and prevention.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Contraind | 2015 |
Review article: the pathophysiology and medical management of diverticulosis and diverticular disease of the colon.
Topics: Anti-Bacterial Agents; Dietary Fiber; Diverticulitis, Colonic; Diverticulum; Humans; Mesalamine; Pro | 2015 |
Changes in the approach to acute diverticulitis.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents; Diverticulitis; Diverticulitis, Colo | 2015 |
New medical strategies for the management of acute diverticulitis.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Colonoscopy; Dietary | 2015 |
Pathophysiology and Therapeutic Strategies for Symptomatic Uncomplicated Diverticular Disease of the Colon.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Dietary Fiber; Diverticulitis, Colon | 2016 |
Mesalamine Does Not Help Prevent Recurrent Acute Colonic Diverticulitis: Meta-Analysis of Randomized, Placebo-Controlled Trials.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Humans; Mesalamine; | 2016 |
Mesalazine for the Treatment of Symptomatic Uncomplicated Diverticular Disease of the Colon and for Primary Prevention of Diverticulitis: A Systematic Review of Randomized Clinical Trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Diverticulosis, Colonic; Female; H | 2016 |
Mesalazine in preventing acute diverticulitis occurrence: a meta-analysis of randomized controlled trials.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Diverticulitis, Col | 2016 |
Therapeutic management of acute uncomplicated diverticulitis.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as To | 2017 |
Balsalazide plus high-potency probiotic preparation (VSL[sharp]3) in the treatment of acute mild-to-moderate ulcerative colitis and uncomplicated diverticulitis of the colon.
Topics: Clinical Trials as Topic; Colitis, Ulcerative; Diverticulitis, Colonic; Drug Therapy, Combination; G | 2008 |
Colonic diverticular disease.
Topics: Acute Disease; Diverticulitis; Diverticulitis, Colonic; Diverticulosis, Colonic; Diverticulum; Human | 2007 |
Review article: the current and evolving treatment of colonic diverticular disease.
Topics: Anti-Bacterial Agents; Dietary Supplements; Diverticulitis, Colonic; Gastrointestinal Agents; Humans | 2009 |
Efficacy of 5-ASA in the treatment of colonic diverticular disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Drug Administration Schedule; Huma | 2010 |
Treatment of diverticular disease of the colon and prevention of acute diverticulitis: a systematic review.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Dietary F | 2011 |
Aminosalicylates.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Colitis; Diverticulitis, Colonic; Humans; Mesalamine | 2012 |
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No | 2012 |
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No | 2012 |
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No | 2012 |
Diverticular disease as a chronic illness: evolving epidemiologic and clinical insights.
Topics: Abdominal Pain; Acute Disease; Age Distribution; Anti-Infective Agents; Anti-Inflammatory Agents, No | 2012 |
Advances in the management of colonic diverticulitis.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Colon; Dietary Fiber; Diverticulitis | 2012 |
Colonic diverticular disease.
Topics: Anti-Infective Agents; Dietary Fiber; Diverticulitis, Colonic; Diverticulum, Colon; Humans; Mesalami | 2003 |
Acute diverticulitis of the colon--current medical therapeutic management.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colon | 2004 |
Colonic diverticular disease.
Topics: Acute Disease; Anti-Infective Agents; Dietary Fiber; Diverticulitis, Colonic; Diverticulum, Colon; H | 2004 |
Mesalazine for diverticular disease of the colon--a new role for an old drug.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Drug Therapy, Combination | 2005 |
Colonic diverticular disease.
Topics: Acute Disease; Anti-Infective Agents; Dietary Fiber; Diverticulitis, Colonic; Diverticulum, Colon; H | 2004 |
Management of diverticular disease is changing.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Diverticulitis, Col | 2006 |
The metabolism of mesalamine and its possible use in colonic diverticulitis as an anti-inflammatory agent.
Topics: Acute Disease; Administration, Oral; Administration, Rectal; Anti-Inflammatory Agents, Non-Steroidal | 2006 |
Use of mesalazine in diverticular disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Disease Progression; Diverticulitis, Colonic; Di | 2006 |
5 trials available for mesalamine and Colonic Diverticulitis
| Article | Year |
|---|---|
Long-term treatment with mesalazine in patients with symptomatic uncomplicated diverticular disease.
Topics: Administration, Oral; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biopsy, Needle; Confidence Inte | 2012 |
Efficacy of mesalazine in the treatment of symptomatic diverticular disease.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analysis of Variance; Diverticulitis, Colonic; | 2005 |
[Modern indications on the medical treatment of symptomatic diverticular disease].
Topics: Aged; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Drug | 2006 |
Balsalazide and/or high-potency probiotic mixture (VSL#3) in maintaining remission after attack of acute, uncomplicated diverticulitis of the colon.
Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Bifidobacterium; Diverticulitis | 2007 |
Prevention of complications and symptomatic recurrences in diverticular disease with mesalazine: a 12-month follow-up.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Barium Sulfate; Colonoscopy | 2007 |
17 other studies available for mesalamine and Colonic Diverticulitis
| Article | Year |
|---|---|
The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Treatment of Left-Sided Colonic Diverticulitis.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Colorectal Surgery; Disease Manageme | 2020 |
Editorial: mesalazine to prevent recurrent acute diverticulitis-the final nail in the coffin. Authors' reply.
Topics: Diverticulitis; Diverticulitis, Colonic; Humans; Mesalamine | 2017 |
Editorial: mesalazine to prevent recurrent acute diverticulitis-the final nail in the coffin. Authors' reply.
Topics: Diverticulitis; Diverticulitis, Colonic; Humans; Mesalamine | 2017 |
Editorial: mesalazine to prevent recurrent acute diverticulitis-the final nail in the coffin. Authors' reply.
Topics: Diverticulitis; Diverticulitis, Colonic; Humans; Mesalamine | 2017 |
Editorial: mesalazine to prevent recurrent acute diverticulitis-the final nail in the coffin. Authors' reply.
Topics: Diverticulitis; Diverticulitis, Colonic; Humans; Mesalamine | 2017 |
Editorial: mesalazine to prevent recurrent acute diverticulitis-the final nail in the coffin.
Topics: Diverticulitis; Diverticulitis, Colonic; Humans; Mesalamine | 2017 |
Editorial: mesalazine to prevent recurrent acute diverticulitis-the final nail in the coffin.
Topics: Diverticulitis; Diverticulitis, Colonic; Humans; Mesalamine | 2017 |
Editorial: mesalazine to prevent recurrent acute diverticulitis-the final nail in the coffin.
Topics: Diverticulitis; Diverticulitis, Colonic; Humans; Mesalamine | 2017 |
Editorial: mesalazine to prevent recurrent acute diverticulitis-the final nail in the coffin.
Topics: Diverticulitis; Diverticulitis, Colonic; Humans; Mesalamine | 2017 |
Effectiveness of different therapeutic strategies in preventing diverticulitis recurrence.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Fe | 2013 |
Intermittent versus every-day mesalazine therapy in preventing complications of diverticular disease: a long-term follow-up study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Di | 2013 |
Mesalamine in Recurrent Acute Colonic Diverticulitis.
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis; Diverticulitis, Colonic; Hum | 2016 |
[Modern therapy of diverticular disease].
Topics: Abscess; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroi | 2008 |
[A case of segmental colitis associated with diverticular disease].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colon, Sigmoid; Colonoscopy; Diverticulitis, Colon | 2010 |
Medical treatment of colonic diverticular disease: are we sure the aim is right?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Female; Humans; Male; Mesalamine | 2012 |
Role of fecal calprotectin in the diagnosis and treatment of segmental colitis associated with diverticulosis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers; Case-Control Studies; Colitis, Ulcerative | 2011 |
Mucosal expression of basic fibroblastic growth factor, Syndecan 1 and tumor necrosis factor-alpha in diverticular disease of the colon: a case-control study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Case | 2012 |
Long-term treatment with mesalazine and rifaximin versus rifaximin alone for patients with recurrent attacks of acute diverticulitis of colon.
Topics: Acute Disease; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Drug Therapy, | 2002 |
Diverticular disease of the colon.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colonic; Diverticulosis, Colonic; Humans; M | 2004 |
Preventive therapy for complicated diverticular disease of the colon: looking for a correct therapeutic approach.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Diverticulitis, Colonic; Humans; | 2004 |
[Course and conservative treatment of diverticular disease].
Topics: Aged, 80 and over; Anti-Bacterial Agents; Cross-Sectional Studies; Diagnosis, Differential; Divertic | 2007 |
Natural history and long-term clinical behavior of segmental colitis associated with diverticulosis (SCAD syndrome).
Topics: Abdominal Pain; Adult; Age Distribution; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Dia | 2008 |
Segmental colitis associated with diverticula: a prospective study. Gruppo di Studio per le Malattie Infiammatorie Intestinali (GSMII).
Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colonoscopy; Diverticulit | 2000 |