mesalamine has been researched along with Colon Diverticula in 19 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six patients (15%) showed recurrence of symptoms: 1 in group A (5." | 2.73 | Continuous versus cyclic mesalazine therapy for patients affected by recurrent symptomatic uncomplicated diverticular disease of the colon. ( Brandimarte, G; Elisei, W; Giorgetti, GM; Tursi, A, 2007) |
| " Mesalazine is as effective as rifaximin (higher dosage schedule) for diminishing some symptoms, but it appears to be better than rifaximin for improving the global score in those patients." | 2.71 | Efficacy of mesalazine in the treatment of symptomatic diverticular disease. ( Aragona, G; Cavallaro, LG; Cavestro, GM; Comparato, G; Di Mario, F; Fanigliulo, L; Franzé, A; Gnocchi, A; Iori, V; Leandro, G; Maino, M; Mazzocchi, G; Moussa, AM, 2005) |
| " Only randomized clinical trials (RCTs) (irrespective of language, blinding, or publication status), which compared mesalazine, irrespective of the dosage assumption, with placebo in SUDD were evaluated." | 2.58 | Mesalazine to treat symptomatic uncomplicated diverticular disease and to prevent acute diverticulitis occurrence. A systematic review with meta-analysis of randomized, placebo-controlled trials. ( Elisei, W; Picchio, M; Tursi, A, 2018) |
| "Diversion colitis and ulcerative colitis (UC) can be caused by different mechanisms; however, several case reports have described the development of typical UC following diversion colitis." | 1.72 | Progression of ulcerative colitis following diversion colitis. ( Araki, K; Inayama, Y; Kimura, H; Kumagai, J; Kunisaki, R; Maeda, S; Matsune, Y; Yaguchi, K, 2022) |
| "As seen in active ulcerative colitis (UC), the formation of crypt abscesses was observed in the biopsy." | 1.42 | A case of diverticular colitis with lesions resembling ulcerative colitis and correlation of tumor necrosis factor-alpha staining with clinical manifestations. ( Inui, K; Katano, Y; Kobayashi, T; Kosaka, T; Torii, Y; Wakabayasi, T; Yoshino, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 10 (52.63) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Yaguchi, K | 1 |
| Matsune, Y | 1 |
| Kunisaki, R | 1 |
| Araki, K | 1 |
| Kimura, H | 1 |
| Inayama, Y | 1 |
| Kumagai, J | 1 |
| Maeda, S | 1 |
| Picchio, M | 3 |
| Elisei, W | 5 |
| Tursi, A | 6 |
| Iannone, A | 1 |
| Ruospo, M | 1 |
| Wong, G | 1 |
| Barone, M | 1 |
| Principi, M | 1 |
| Di Leo, A | 1 |
| Strippoli, GFM | 1 |
| Brandimarte, G | 4 |
| Forti, G | 1 |
| Pianese, G | 1 |
| Rodino, S | 1 |
| D'Amico, T | 1 |
| Sacca, N | 1 |
| Portincasa, P | 1 |
| Capezzuto, E | 1 |
| Lattanzio, R | 1 |
| Spadaccini, A | 1 |
| Fiorella, S | 1 |
| Polimeni, F | 1 |
| Polimeni, N | 1 |
| Stoppino, V | 1 |
| Stoppino, G | 1 |
| Giorgetti, GM | 3 |
| Aiello, F | 1 |
| Danese, S | 1 |
| Di Mario, F | 2 |
| Loperfido, S | 1 |
| Dal Bo', N | 1 |
| Ferrara, F | 1 |
| Marcello, R | 1 |
| Heras Salvat, H | 1 |
| Scarpignato, C | 1 |
| Binda, GA | 1 |
| Cuomo, R | 2 |
| Laghi, A | 1 |
| Nascimbeni, R | 1 |
| Serventi, A | 1 |
| Bellini, D | 1 |
| Gervaz, P | 1 |
| Annibale, B | 2 |
| Torii, Y | 1 |
| Katano, Y | 1 |
| Yoshino, J | 1 |
| Inui, K | 1 |
| Wakabayasi, T | 1 |
| Kobayashi, T | 1 |
| Kosaka, T | 1 |
| Festi, D | 1 |
| Colecchia, A | 1 |
| Maconi, G | 1 |
| Barbara, G | 1 |
| Bosetti, C | 1 |
| Simpson, J | 4 |
| Spiller, R | 4 |
| Aragona, G | 1 |
| Leandro, G | 1 |
| Comparato, G | 1 |
| Fanigliulo, L | 1 |
| Cavallaro, LG | 1 |
| Cavestro, GM | 1 |
| Iori, V | 1 |
| Maino, M | 1 |
| Moussa, AM | 1 |
| Gnocchi, A | 1 |
| Mazzocchi, G | 1 |
| Franzé, A | 1 |
| Petruzziello, L | 1 |
| Iacopini, F | 1 |
| Bulajic, M | 1 |
| Shah, S | 1 |
| Costamagna, G | 1 |
| Tripodi, J | 1 |
| Gorcey, S | 1 |
| Burakoff, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Mesalazine and/or Lactobacillus Casei in Maintaining Remission of Symptomatic Uncomplicated Diverticular Disease of the Colon: a Double-blind, Double-dummy, Placebo-controlled Study[NCT01534754] | Phase 4 | 250 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| Randomized Multicentric Controlled Clinical Trial of Parallel Groups to Evaluate the Non-therapeutic Inferiority of a Free Diet With a Progressive Diet, in the Treatment of Non-complicated Acute Diverticulitis[NCT03496090] | 134 participants (Actual) | Interventional | 2018-04-16 | Completed | |||
| Diverticular Disease Register (REMAD)[NCT03325829] | 1,217 participants (Actual) | Observational [Patient Registry] | 2015-04-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for mesalamine and Colon Diverticula
| Article | Year |
|---|---|
Mesalazine to treat symptomatic uncomplicated diverticular disease and to prevent acute diverticulitis occurrence. A systematic review with meta-analysis of randomized, placebo-controlled trials.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Diverticulit | 2018 |
Mesalazine for People with Diverticular Disease: A Systematic Review of Randomized Controlled Trials.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticular Diseases; Diverticulitis; Diverticulum, Colon; | 2018 |
Treatment of diverticular disease of the colon and prevention of acute diverticulitis: a systematic review.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Combined Modality Therapy; Dietary F | 2011 |
Colonic diverticular disease.
Topics: Anti-Infective Agents; Dietary Fiber; Diverticulitis, Colonic; Diverticulum, Colon; Humans; Mesalami | 2003 |
Acute diverticulitis of the colon--current medical therapeutic management.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis, Colon | 2004 |
Colonic diverticular disease.
Topics: Acute Disease; Anti-Infective Agents; Dietary Fiber; Diverticulitis, Colonic; Diverticulum, Colon; H | 2004 |
Colonic diverticular disease.
Topics: Acute Disease; Anti-Infective Agents; Dietary Fiber; Diverticulitis, Colonic; Diverticulum, Colon; H | 2004 |
Colonic diverticular disease.
Topics: Acute Disease; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Dietary Fiber; Divert | 2005 |
Review article: uncomplicated diverticular disease of the colon.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Collagen; Colon; Colonoscopy; Dietar | 2006 |
3 trials available for mesalamine and Colon Diverticula
| Article | Year |
|---|---|
Randomised clinical trial: mesalazine and/or probiotics in maintaining remission of symptomatic uncomplicated diverticular disease--a double-blind, randomised, placebo-controlled study.
Topics: Abdominal Pain; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diverticulum, Colon; Double-Blind Met | 2013 |
Efficacy of mesalazine in the treatment of symptomatic diverticular disease.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Analysis of Variance; Diverticulitis, Colonic; | 2005 |
Continuous versus cyclic mesalazine therapy for patients affected by recurrent symptomatic uncomplicated diverticular disease of the colon.
Topics: Aged; Aged, 80 and over; Diverticulum, Colon; Female; Humans; Male; Mesalamine; Middle Aged; Prospec | 2007 |
7 other studies available for mesalamine and Colon Diverticula
| Article | Year |
|---|---|
Progression of ulcerative colitis following diversion colitis.
Topics: Colitis; Colitis, Ulcerative; Colonoscopy; Diverticulum, Colon; Humans; Male; Mesalamine; Middle Age | 2022 |
Intermittent versus every-day mesalazine therapy in preventing complications of diverticular disease: a long-term follow-up study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Distribution; Di | 2013 |
Practice parameters for the treatment of colonic diverticular disease: Italian Society of Colon and Rectal Surgery (SICCR) guidelines.
Topics: Abscess; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Colectomy; Colon; Colonogra | 2015 |
A case of diverticular colitis with lesions resembling ulcerative colitis and correlation of tumor necrosis factor-alpha staining with clinical manifestations.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis; Colitis, Ulcerative; Colonoscopy; Diverticulum, Co | 2015 |
Mesalazine and rifaximin in symptomatic uncomplicated diverticular disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diverticulitis; Diverticulum, Colon; Gastrointestinal Agent | 2009 |
Transient lactose malabsorption in patients affected by symptomatic uncomplicated diverticular disease of the colon.
Topics: Adult; Age Distribution; Aged; Aged, 80 and over; Breath Tests; Case-Control Studies; Diverticulum, | 2006 |
A case of diversion colitis treated with 5-aminosalicylic acid enemas.
Topics: Aged; Aged, 80 and over; Aminosalicylic Acids; Colitis; Colostomy; Diverticulum, Colon; Enema; Femal | 1992 |