Page last updated: 2024-10-30

mesalamine and Colitis, Collagenous

mesalamine has been researched along with Colitis, Collagenous in 14 studies

Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.

Colitis, Collagenous: A subtype of MICROSCOPIC COLITIS, characterized by chronic watery DIARRHEA of unknown origin, a normal COLONOSCOPY but abnormal histopathology on BIOPSY. Microscopic examination of biopsy samples taken from the COLON show larger-than-normal band of subepithelial COLLAGEN.

Research Excerpts

ExcerptRelevanceReference
"Patients with active collagenous colitis were randomly assigned to groups given pH-modified release oral budesonide capsules (9 mg budesonide once daily, Budenofalk, n = 30), mesalamine granules (3 g mesalamine once daily, Salofalk, n = 25), or placebo for 8 weeks (n = 37) in a double-blind, double-dummy fashion."9.19Budesonide is more effective than mesalamine or placebo in short-term treatment of collagenous colitis. ( Böhm, G; Bonderup, OK; Fernández-Bañares, F; Greinwald, R; Kupcinskas, L; Madisch, A; Marks, HJ; Miehlke, S; Mohrbacher, R; Nathan, T; Neumeyer, M; Petrauskas, D; Vieth, M, 2014)
"Patients with active collagenous colitis were randomly assigned to groups given pH-modified release oral budesonide capsules (9 mg budesonide once daily, Budenofalk, n = 30), mesalamine granules (3 g mesalamine once daily, Salofalk, n = 25), or placebo for 8 weeks (n = 37) in a double-blind, double-dummy fashion."5.19Budesonide is more effective than mesalamine or placebo in short-term treatment of collagenous colitis. ( Böhm, G; Bonderup, OK; Fernández-Bañares, F; Greinwald, R; Kupcinskas, L; Madisch, A; Marks, HJ; Miehlke, S; Mohrbacher, R; Nathan, T; Neumeyer, M; Petrauskas, D; Vieth, M, 2014)
"Microscopic colitis is a common cause of chronic watery diarrhea with a great impact on patient quality of life."2.66Treatment of microscopic colitis: the role of budesonide and new alternatives for refractory patients. ( Casanova, MJ; Gisbert, JP; Rojo, E, 2020)
"Collagenous colitis is a cause of chronic diarrhea."2.55Interventions for treating collagenous colitis. ( Chande, N; Kafil, TS; MacDonald, JK; McDonald, JW; Nguyen, TM; Patton, PH, 2017)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (35.71)29.6817
2010's8 (57.14)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Rojo, E1
Casanova, MJ1
Gisbert, JP1
Kafil, TS1
Nguyen, TM1
Patton, PH1
MacDonald, JK1
Chande, N1
McDonald, JW1
Miehlke, S2
Madisch, A2
Kupcinskas, L1
Petrauskas, D1
Böhm, G1
Marks, HJ1
Neumeyer, M1
Nathan, T1
Fernández-Bañares, F1
Greinwald, R2
Mohrbacher, R2
Vieth, M1
Bonderup, OK2
Drug, VL1
Antoniu, SA1
Münch, A1
Tysk, C1
Bohr, J1
Mueller, R1
Ström, M1
Silva, M1
Nunes, AC1
Andrade, P1
Gomes, S1
Macedo, G1
Pardi, DS1
Suzuki, K1
Kawabe, T1
Takahashi, H1
Nakao, S1
Suzuki, A1
Inamori, M1
Iida, H1
Endo, H1
Akiyama, T1
Fujita, K1
Yoneda, M1
Abe, Y1
Kobayashi, N1
Kubota, K1
Oshiro, H1
Nakajima, A1
Hashimoto, Y1
Endo, Y1
Kuroki, Y1
Yoshikumi, H1
Yoshiba, M1
Calabrese, C1
Gionchetti, P1
Liguori, G1
Areni, A1
Fornarini, GS1
Campieri, M1
Rizzello, F1
Denız, K1
Coban, G1
Ozbakir, O1
Denız, E1
Narváez, J1
Montala, N1
Busquets-Pérez, N1
Nolla, JM1
Valverde, J1
Koch, D1
Sinha, A1
Greenaway, JR1
Carmichael, AJ1
de la Iglesia Fanjul, I1
de Castro Losa, MR1
Izquierdo García, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Double-blind, Double-dummy, Randomised, Placebo-controlled, Multi-centre Phase III Clinical Study on the Efficacy and Tolerability of Budesonide Capsules vs. Mesalazine Granules vs. Placebo for Patients With Collagenous Colitis.[NCT00450086]Phase 392 participants (Actual)Interventional2007-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for mesalamine and Colitis, Collagenous

ArticleYear
Treatment of microscopic colitis: the role of budesonide and new alternatives for refractory patients.
    Revista espanola de enfermedades digestivas, 2020, Volume: 112, Issue:1

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antidiarrheals; Antimetabolites; Azathioprine; Bi

2020
Interventions for treating collagenous colitis.
    The Cochrane database of systematic reviews, 2017, 11-11, Volume: 11

    Topics: Bismuth; Boswellia; Budesonide; Cholestyramine Resin; Chronic Disease; Colitis, Collagenous; Diarrhe

2017
Diagnosis and Management of Microscopic Colitis.
    The American journal of gastroenterology, 2017, Volume: 112, Issue:1

    Topics: Anion Exchange Resins; Anti-Inflammatory Agents, Non-Steroidal; Antidiarrheals; Autoimmunity; Bile A

2017

Trials

3 trials available for mesalamine and Colitis, Collagenous

ArticleYear
Budesonide is more effective than mesalamine or placebo in short-term treatment of collagenous colitis.
    Gastroenterology, 2014, Volume: 146, Issue:5

    Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Budesonide; Capsules; Colitis, Collagen

2014
Smoking Status Influences Clinical Outcome in Collagenous Colitis.
    Journal of Crohn's & colitis, 2016, Volume: 10, Issue:4

    Topics: Aged; Budesonide; Colitis, Collagenous; Colon; Female; Gastrointestinal Agents; Humans; Male; Mesala

2016
Clinical course of microscopic colitis in a single-center cohort study.
    Journal of Crohn's & colitis, 2011, Volume: 5, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Cholestyramine Resin; Coho

2011

Other Studies

8 other studies available for mesalamine and Colitis, Collagenous

ArticleYear
Efficacy of budesonide in collagenous colitis Evaluation of: Miehlke S, Madisch A, Kupcinskas L, et al. Budesonide is more effective than mesalamine or placebo in short-term treatment of collagenous colitis. Gastroenterology 2014;146(5):1222-1230 e1222.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:15

    Topics: Anti-Inflammatory Agents; Budesonide; Colitis, Collagenous; Female; Gastrointestinal Agents; Humans;

2014
Collagenous colitis and Crohn's disease: Guilty or innocent bystander?
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2016, Volume: 48, Issue:10

    Topics: Aged; Budesonide; Colitis, Collagenous; Colon; Colonoscopy; Crohn Disease; Humans; Male; Mesalamine;

2016
Collagenous colitis in a Japanese woman: successful treatment with mesalazine.
    Digestion, 2008, Volume: 77, Issue:3-4

    Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Collagenous; Colon; Female; Hum

2008
Collagenous colitis with unique colonoscopic findings.
    Endoscopy, 2008, Volume: 40 Suppl 2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Colitis, Collagenous; Colonoscopy; Diagnosis,

2008
Pseudomembranous collagenous colitis.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2012, Volume: 23, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Collagenous; Colonoscopy; Diarrhea; Enterocolitis,

2012
Collagenous colitis and spondylarthropathy.
    Arthritis and rheumatism, 2006, Jun-15, Volume: 55, Issue:3

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Collagenous; Drug Therapy, Combination; Fem

2006
Pyoderma gangrenosum associated with collagenous colitis.
    Clinical and experimental dermatology, 2007, Volume: 32, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Collagenous; Female; Humans; Mesalamine; Middle Ag

2007
[Collagenous colitis. Clinicopathological study of 18 cases].
    Revista clinica espanola, 2007, Volume: 207, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; B

2007