mesalamine has been researched along with Chromosomal Instability in 2 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Chromosomal Instability: An increased tendency to acquire CHROMOSOME ABERRATIONS when various processes involved in chromosome replication, repair, or segregation are dysfunctional.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In familial and sporadic colorectal cancer, aspirin, other nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 inhibitors have been tested for their ability to reduce polyp and cancer development in clinical studies." | 2.42 | Review article: the chemoprevention of colorectal carcinoma. ( Gasche, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Da-Silva, N | 1 |
| Arasaradnam, R | 1 |
| Getliffe, K | 1 |
| Sung, E | 1 |
| Oo, Y | 1 |
| Nwokolo, C | 1 |
| Gasche, C | 1 |
1 review available for mesalamine and Chromosomal Instability
| Article | Year |
|---|---|
Review article: the chemoprevention of colorectal carcinoma.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Chemoprevention; Chromosoma | 2004 |
1 other study available for mesalamine and Chromosomal Instability
| Article | Year |
|---|---|
Altered mRNA expression of telomere binding proteins (TPP1, POT1, RAP1, TRF1 and TRF2) in ulcerative colitis and Crohn's disease.
Topics: Azathioprine; Biomarkers, Tumor; Chromosomal Instability; Colitis, Ulcerative; Colon; Colonic Neopla | 2010 |