mesalamine has been researched along with Cholestasis in 3 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Cholestasis: Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " This case reinforces the possibility of a causal relationship between mesalazine therapy and toxic hepatic injury without systemic hypersensitivity." | 1.62 | "Hepatotoxicity in inflammatory bowel disease: mesalazine, the forgotten drug". ( Garrido, I; Lopes, J; Lopes, S; Macedo, G; Santos, AL, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Garrido, I | 1 |
| Santos, AL | 1 |
| Lopes, J | 1 |
| Lopes, S | 1 |
| Macedo, G | 1 |
| Stelzer, T | 1 |
| Kohler, S | 1 |
| Marques Maggio, E | 1 |
| Heuss, LT | 1 |
| Stoschus, B | 1 |
| Meybehm, M | 1 |
| Spengler, U | 1 |
| Scheurlen, C | 1 |
| Sauerbruch, T | 1 |
3 other studies available for mesalamine and Cholestasis
| Article | Year |
|---|---|
"Hepatotoxicity in inflammatory bowel disease: mesalazine, the forgotten drug".
Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug Induced Liver Injury; Cholestasis; Coliti | 2021 |
An unusual cause of febrile hepatitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis | 2015 |
Cholestasis associated with mesalazine therapy in a patient with Crohn's disease.
Topics: Adult; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Cholestasis; Crohn Disease; Hu | 1997 |