mesalamine has been researched along with Cell Transformation, Neoplastic in 7 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Most colorectal cancers (CRC) arise sporadically from precursor lesions: colonic polyps." | 1.62 | 5-Aminosalicylic acid inhibits stem cell function in human adenoma-derived cells: implications for chemoprophylaxis in colorectal tumorigenesis. ( Chambers, AC; Collard, TJ; Creed, TJ; Dixon, SW; Greenhough, A; Legge, DN; Mortensson, EMH; Williams, AC, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Dixon, SW | 1 |
| Collard, TJ | 1 |
| Mortensson, EMH | 1 |
| Legge, DN | 1 |
| Chambers, AC | 1 |
| Greenhough, A | 1 |
| Creed, TJ | 1 |
| Williams, AC | 1 |
| Do, EJ | 1 |
| Hwang, SW | 1 |
| Kim, SY | 1 |
| Ryu, YM | 1 |
| Cho, EA | 1 |
| Chung, EJ | 1 |
| Park, S | 1 |
| Lee, HJ | 1 |
| Byeon, JS | 1 |
| Ye, BD | 1 |
| Yang, DH | 1 |
| Park, SH | 1 |
| Yang, SK | 1 |
| Kim, JH | 1 |
| Myung, SJ | 1 |
| Chen, J | 1 |
| Huang, XF | 1 |
| Kisiel, JB | 1 |
| Loftus, EV | 1 |
| Harmsen, WS | 1 |
| Zinsmeister, AR | 1 |
| Sandborn, WJ | 1 |
| Actis, GC | 1 |
| Tarallo, S | 1 |
| Rosina, F | 1 |
| Narisawa, T | 1 |
| Fukaura, Y | 1 |
| Bernstein, CN | 1 |
2 reviews available for mesalamine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Cutting edge: chemoprevention of colorectal neoplasia in inflammatory bowel disease.
Topics: Animals; Anti-Inflammatory Agents; Cell Transformation, Neoplastic; Chemoprevention; Colonoscopy; Co | 2013 |
Ulcerative colitis with low-grade dysplasia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cell Transformation, Neoplastic; Colectomy; Colitis, | 2004 |
5 other studies available for mesalamine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
5-Aminosalicylic acid inhibits stem cell function in human adenoma-derived cells: implications for chemoprophylaxis in colorectal tumorigenesis.
Topics: Adenoma; Carcinogenesis; Carcinoma; Cell Line, Tumor; Cell Transformation, Neoplastic; Chemopreventi | 2021 |
Suppression of colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway by balsalazide and VSL#3.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Azoxymethane; bcl-2-Assoc | 2016 |
Beta-catenin pathway in ulcerative colitis-associated colorectal cancer and therapeutic implication.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Cell Transformation, Neoplastic; Col | 2009 |
Outcome of sporadic adenomas and adenoma-like dysplasia in patients with ulcerative colitis undergoing polypectomy.
Topics: Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cell T | 2012 |
Prevention by intrarectal 5-aminosalicylic acid of N-methylnitrosourea-induced colon cancer in F344 rats.
Topics: Administration, Rectal; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Transformation, Neopl | 2003 |