mesalamine has been researched along with Carcinogenesis in 4 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study represents the first evidence that combination therapy with balsalazide and parthenolide could be a new regimen for colorectal cancer treatment." | 3.85 | Combined Parthenolide and Balsalazide Have Enhanced Antitumor Efficacy Through Blockade of NF-κB Activation. ( Jeong, HJ; Kim, EM; Kim, IH; Kim, SH; Kim, SL; Kim, SW; Kim, YN; Lee, SO; Lee, ST; Liu, YC; Park, YR; Seo, SY, 2017) |
| "Most colorectal cancers (CRC) arise sporadically from precursor lesions: colonic polyps." | 1.62 | 5-Aminosalicylic acid inhibits stem cell function in human adenoma-derived cells: implications for chemoprophylaxis in colorectal tumorigenesis. ( Chambers, AC; Collard, TJ; Creed, TJ; Dixon, SW; Greenhough, A; Legge, DN; Mortensson, EMH; Williams, AC, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, J | 1 |
| Li, H | 1 |
| Chen, J | 1 |
| He, L | 1 |
| Du, X | 1 |
| Zhou, L | 1 |
| Xiong, Q | 1 |
| Lai, X | 1 |
| Yang, Y | 1 |
| Huang, S | 1 |
| Hou, S | 1 |
| Dixon, SW | 1 |
| Collard, TJ | 1 |
| Mortensson, EMH | 1 |
| Legge, DN | 1 |
| Chambers, AC | 1 |
| Greenhough, A | 1 |
| Creed, TJ | 1 |
| Williams, AC | 1 |
| Dammann, K | 1 |
| Khare, V | 1 |
| Harpain, F | 1 |
| Lang, M | 1 |
| Kurtovic, A | 1 |
| Mesteri, I | 1 |
| Evstatiev, R | 1 |
| Gasche, C | 1 |
| Kim, SL | 1 |
| Kim, SH | 1 |
| Park, YR | 1 |
| Liu, YC | 1 |
| Kim, EM | 1 |
| Jeong, HJ | 1 |
| Kim, YN | 1 |
| Seo, SY | 1 |
| Kim, IH | 1 |
| Lee, SO | 1 |
| Lee, ST | 1 |
| Kim, SW | 1 |
4 other studies available for mesalamine and Carcinogenesis
| Article | Year |
|---|---|
Dendrobium officinale polysaccharides alleviate colon tumorigenesis via restoring intestinal barrier function and enhancing anti-tumor immune response.
Topics: Animals; Antineoplastic Agents; Carcinogenesis; CD8-Positive T-Lymphocytes; Colitis; Colon; Colorect | 2019 |
5-Aminosalicylic acid inhibits stem cell function in human adenoma-derived cells: implications for chemoprophylaxis in colorectal tumorigenesis.
Topics: Adenoma; Carcinogenesis; Carcinoma; Cell Line, Tumor; Cell Transformation, Neoplastic; Chemopreventi | 2021 |
PAK1 promotes intestinal tumor initiation.
Topics: Animals; Azoxymethane; beta Catenin; Carcinogenesis; Colonoscopy; Dextrans; Female; Gene Deletion; G | 2015 |
Combined Parthenolide and Balsalazide Have Enhanced Antitumor Efficacy Through Blockade of NF-κB Activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Ap | 2017 |