Page last updated: 2024-10-30

mesalamine and Cancer of Intestines

mesalamine has been researched along with Cancer of Intestines in 8 studies

Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.

Research Excerpts

ExcerptRelevanceReference
"The relative risk of colorectal cancer in ulcerative colitis is increased, however, there're marked geographically differences."2.43[Inflammatory bowel disease and colorectal cancer]. ( Hagymási, K; Tulassay, Z, 2006)
"The medical records of patients with Crohn's disease (CD) and ulcerative colitis (UC) diagnosed with IBD-associated intestinal neoplasia (dysplasia or cancer) from 1983 to 2020 were included in this study."1.91Effect of Biologics on the Risk of Advanced-Stage Inflammatory Bowel Disease-Associated Intestinal Cancer: A Nationwide Study. ( Ajioka, Y; Akagi, Y; Arakaki, J; Daito, K; Futami, K; Goi, T; Hanai, T; Hasegawa, J; Hida, K; Ikeuchi, H; Iseki, Y; Ishida, F; Ishihara, S; Itabashi, M; Kanemitsu, Y; Katsumata, K; Kazama, S; Kimura, H; Kinugasa, Y; Kiyomatsu, T; Komori, K; Koyama, F; Maeda, K; Maemoto, A; Matsuda, K; Nakamura, M; Nezu, R; Noake, T; Noguchi, T; Ogino, T; Ohge, H; Okabayashi, K; Okamoto, K; Okuda, J; Sasaki, S; Sato, Y; Seishima, R; Shida, D; Sugihara, K; Sunami, E; Suto, T; Takahashi, K; Toiyama, Y; Uchino, M; Uehara, K; Ueno, H; Wakai, T; Watanabe, K; Yamada, K; Yamada, T; Yamaguchi, S; Yamamoto, S; Yamamoto, T, 2023)
"No significant risk for other intestinal cancers was found, especially for small bowel carcinoma."1.43Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study. ( Charpentier, C; Cheddani, H; Dauchet, L; Dupas, JL; Fumery, M; Gower-Rousseau, C; Marie Bouvier, A; Pariente, B; Peyrin-Biroulet, L; Savoye, G, 2016)
"Data from all patients with Crohn's disease whose diagnosis had been performed before 1st January 1978 were analyzed."1.32Crohn's disease over 20 years after diagnosis in a referral population. ( Beaugerie, L; Bouhnik, Y; Cosnes, J; Etienney, I; Gendre, JP; Lémann, M; Matuchansky, C; Modigliani, R; Rambaud, JC, 2004)
" To directly evaluate the ability of 5-ASA to suppress intestinal tumors, we studied several formulations of 5-ASA (free acid, sulfasalazine, and Pentasa) at multiple oral dosage levels [500, 2400, 4800, and 9600 parts/million (ppm)] in the adenomatous polyposis coli (Apc) mouse model of multiple intestinal neoplasia (Min)."1.30Evaluation of 5-aminosalicylic acid (5-ASA) for cancer chemoprevention: lack of efficacy against nascent adenomatous polyps in the Apc(Min) mouse. ( Gendler, SJ; Hirsch, RE; Leighton, JA; Morrow, JD; Ritland, SR; Weaver, AL, 1999)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Seishima, R1
Okabayashi, K1
Ikeuchi, H1
Uchino, M1
Futami, K1
Noguchi, T1
Ohge, H1
Iseki, Y1
Watanabe, K1
Itabashi, M1
Okamoto, K1
Toiyama, Y1
Ogino, T1
Nakamura, M1
Yamada, K1
Wakai, T1
Sato, Y1
Kimura, H1
Takahashi, K1
Hida, K1
Kinugasa, Y1
Ishida, F1
Okuda, J1
Daito, K1
Koyama, F1
Ueno, H1
Yamamoto, T1
Yamamoto, S1
Hanai, T1
Maemoto, A1
Arakaki, J1
Komori, K1
Akagi, Y1
Shida, D1
Yamaguchi, S1
Matsuda, K1
Maeda, K1
Noake, T1
Nezu, R1
Sasaki, S1
Hasegawa, J1
Sunami, E1
Kanemitsu, Y1
Katsumata, K1
Uehara, K1
Kiyomatsu, T1
Suto, T1
Kazama, S1
Yamada, T1
Goi, T1
Ishihara, S1
Ajioka, Y1
Sugihara, K1
Dammann, K1
Khare, V1
Harpain, F1
Lang, M1
Kurtovic, A1
Mesteri, I1
Evstatiev, R1
Gasche, C1
Cheddani, H1
Dauchet, L1
Fumery, M1
Charpentier, C1
Marie Bouvier, A1
Dupas, JL1
Pariente, B1
Peyrin-Biroulet, L1
Savoye, G1
Gower-Rousseau, C1
Etienney, I1
Bouhnik, Y1
Gendre, JP1
Lémann, M1
Cosnes, J1
Matuchansky, C1
Beaugerie, L1
Modigliani, R1
Rambaud, JC1
Hagymási, K1
Tulassay, Z1
Veldman, W1
van Beek, M1
Keuning, JJ1
Driessen, WM1
Ritland, SR1
Leighton, JA1
Hirsch, RE1
Morrow, JD1
Weaver, AL1
Gendler, SJ1
MacGregor, DJ1
Kim, YS1
Sleisenger, MH1
Johnson, LK1

Reviews

1 review available for mesalamine and Cancer of Intestines

ArticleYear
[Inflammatory bowel disease and colorectal cancer].
    Orvosi hetilap, 2006, Oct-15, Volume: 147, Issue:41

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cholangitis, Sclerosing; Colitis, Ulcerative; Colonoscopy;

2006

Other Studies

7 other studies available for mesalamine and Cancer of Intestines

ArticleYear
Effect of Biologics on the Risk of Advanced-Stage Inflammatory Bowel Disease-Associated Intestinal Cancer: A Nationwide Study.
    The American journal of gastroenterology, 2023, 07-01, Volume: 118, Issue:7

    Topics: Biological Products; Colitis, Ulcerative; Crohn Disease; Humans; Immunologic Factors; Inflammatory B

2023
PAK1 promotes intestinal tumor initiation.
    Cancer prevention research (Philadelphia, Pa.), 2015, Volume: 8, Issue:11

    Topics: Animals; Azoxymethane; beta Catenin; Carcinogenesis; Colonoscopy; Dextrans; Female; Gene Deletion; G

2015
Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study.
    The American journal of gastroenterology, 2016, Volume: 111, Issue:10

    Topics: Adrenal Cortex Hormones; Age of Onset; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroi

2016
Crohn's disease over 20 years after diagnosis in a referral population.
    Gastroenterologie clinique et biologique, 2004, Volume: 28, Issue:12

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Az

2004
Regional enteritis complicating malignant lymphoma.
    The Netherlands journal of medicine, 1996, Volume: 49, Issue:2

    Topics: Adult; Aminosalicylic Acids; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Anti

1996
Evaluation of 5-aminosalicylic acid (5-ASA) for cancer chemoprevention: lack of efficacy against nascent adenomatous polyps in the Apc(Min) mouse.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:4

    Topics: Adenomatous Polyps; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Chemo

1999
Chemoprevention of colon cancer carcinogenesis by balsalazide: inhibition of azoxymethane-induced aberrant crypt formation in the rat colon and intestinal tumor formation in the B6-Min/+ mouse.
    International journal of oncology, 2000, Volume: 17, Issue:1

    Topics: Aminosalicylic Acids; Animals; Anti-Ulcer Agents; Anticarcinogenic Agents; Azoxymethane; Cell Divisi

2000