mesalamine has been researched along with Benign Neoplasms in 14 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| "For development of targeted cancer therapy, attention is given to kinases rather than phosphatases inhibitors." | 1.51 | Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types. ( Abdu-Allah, H; Al-Azawi, AM; El-Awady, R; El-Shorbagi, AN; Menon, V; Ramadan, W; Saleh, E; Tarazi, H; Vazhappilly, CG, 2019) |
| "Mesalamine were the most frequently used medications." | 1.48 | Inflammatory bowel disease in patients over the age of 70 y. Does the disease duration influence its behavior? ( Bosca-Watts, MM; Cortes, X; Gil, R; Hervás, D; Huguet, JM; Iborra, M; Maroto, N; Paredes, JM, 2018) |
| "No significant risk for other intestinal cancers was found, especially for small bowel carcinoma." | 1.43 | Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study. ( Charpentier, C; Cheddani, H; Dauchet, L; Dupas, JL; Fumery, M; Gower-Rousseau, C; Marie Bouvier, A; Pariente, B; Peyrin-Biroulet, L; Savoye, G, 2016) |
| "The risk of colorectal cancer is increased in patients with inflammatory bowel diseases, especially those with ulcerative colitis (UC)." | 1.34 | 5-aminosalicylic acid given in the remission stage of colitis suppresses colitis-associated cancer in a mouse colitis model. ( Endo, H; Fujisawa, T; Fujita, K; Ikeda, I; Inamori, M; Kubota, K; Nagashima, Y; Nakagama, H; Nakajima, A; Nozaki, Y; Saito, S; Takahashi, H; Tomimoto, A; Wada, K; Yoneda, M; Yonemitsu, K, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Bansal, Y | 1 |
| Kaur, M | 1 |
| Silakari, O | 1 |
| Tang-Fichaux, M | 1 |
| Branchu, P | 1 |
| Nougayrède, JP | 1 |
| Oswald, E | 1 |
| Mouhtar El Hálabi, S | 1 |
| Valdés Delgado, T | 1 |
| Maldonado Pérez, B | 1 |
| Belvis Jiménez, M | 1 |
| Argüelles Arias, F | 1 |
| Bonovas, S | 1 |
| Fiorino, G | 1 |
| Lytras, T | 1 |
| Nikolopoulos, G | 1 |
| Peyrin-Biroulet, L | 2 |
| Danese, S | 1 |
| Collins, PD | 1 |
| Vazhappilly, CG | 1 |
| Saleh, E | 1 |
| Ramadan, W | 1 |
| Menon, V | 1 |
| Al-Azawi, AM | 1 |
| Tarazi, H | 1 |
| Abdu-Allah, H | 1 |
| El-Shorbagi, AN | 2 |
| El-Awady, R | 2 |
| Huguet, JM | 1 |
| Iborra, M | 1 |
| Bosca-Watts, MM | 1 |
| Maroto, N | 1 |
| Gil, R | 1 |
| Cortes, X | 1 |
| Hervás, D | 1 |
| Paredes, JM | 1 |
| Korczynska, M | 1 |
| Le, DD | 1 |
| Younger, N | 1 |
| Gregori-Puigjané, E | 1 |
| Tumber, A | 1 |
| Krojer, T | 1 |
| Velupillai, S | 1 |
| Gileadi, C | 1 |
| Nowak, RP | 1 |
| Iwasa, E | 1 |
| Pollock, SB | 1 |
| Ortiz Torres, I | 1 |
| Oppermann, U | 1 |
| Shoichet, BK | 1 |
| Fujimori, DG | 1 |
| Abdu-Allah, HH | 1 |
| Abdel-Moty, SG | 1 |
| Cheddani, H | 1 |
| Dauchet, L | 1 |
| Fumery, M | 1 |
| Charpentier, C | 1 |
| Marie Bouvier, A | 1 |
| Dupas, JL | 1 |
| Pariente, B | 1 |
| Savoye, G | 1 |
| Gower-Rousseau, C | 1 |
| Taubert, D | 1 |
| Berkels, R | 1 |
| Schömig, E | 1 |
| Winther, KV | 1 |
| Jess, T | 1 |
| Langholz, E | 1 |
| Munkholm, P | 1 |
| Binder, V | 1 |
| Ikeda, I | 1 |
| Tomimoto, A | 1 |
| Wada, K | 1 |
| Fujisawa, T | 1 |
| Fujita, K | 1 |
| Yonemitsu, K | 1 |
| Nozaki, Y | 1 |
| Endo, H | 1 |
| Takahashi, H | 1 |
| Yoneda, M | 1 |
| Inamori, M | 1 |
| Kubota, K | 1 |
| Saito, S | 1 |
| Nagashima, Y | 1 |
| Nakagama, H | 1 |
| Nakajima, A | 1 |
3 reviews available for mesalamine and Benign Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
Tackling the Threat of Cancer Due to Pathobionts Producing Colibactin: Is Mesalamine the Magic Bullet?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Escherichia coli; Humans; Mesalamine; Neoplasms; Peptides; | 2021 |
[Aspirin--a suitable drug for cancer prevention?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cost-Benefit Analysis; Cyclooxygenase Inhibitors; | 2004 |
11 other studies available for mesalamine and Benign Neoplasms
| Article | Year |
|---|---|
Benzimidazole--ibuprofen/mesalamine conjugates: potential candidates for multifactorial diseases.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Benzimidazoles; Edema; Ibup | 2015 |
Severe outbreak of ulcerative colitis and cerebral neoplasia. Difficult management in COVID time.
Topics: Colitis, Ulcerative; COVID-19; Disease Outbreaks; Humans; Male; Mesalamine; Middle Aged; Neoplasms | 2023 |
Editorial: evidence is growing for protective effects of 5-aminosalicylates against colitis-associated cancer-authors' reply.
Topics: Colitis; Colitis, Ulcerative; Humans; Mesalamine; Neoplasms | 2017 |
Editorial: evidence is growing for protective effects of 5-aminosalicylates against colitis-associated cancer.
Topics: Colitis; Colitis, Ulcerative; Humans; Mesalamine; Neoplasms | 2017 |
Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types.
Topics: Apoptosis; Cell Movement; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Neoplas | 2019 |
Inflammatory bowel disease in patients over the age of 70 y. Does the disease duration influence its behavior?
Topics: Adrenal Cortex Hormones; Aged; Aged, 80 and over; Comorbidity; Cross-Sectional Studies; Disease Prog | 2018 |
Docking and Linking of Fragments To Discover Jumonji Histone Demethylase Inhibitors.
Topics: Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Humans; Jumonji Domain-Containing Histone De | 2016 |
Design and synthesis of novel 5-aminosalicylate (5-ASA)-4-thiazolinone hybrid derivatives with promising antiproliferative activity.
Topics: Antineoplastic Agents; Cell Proliferation; Humans; MCF-7 Cells; Mesalamine; Models, Molecular; Neopl | 2016 |
Cancer in Elderly Onset Inflammatory Bowel Disease: A Population-Based Study.
Topics: Adrenal Cortex Hormones; Age of Onset; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroi | 2016 |
Long-term risk of cancer in ulcerative colitis: a population-based cohort study from Copenhagen County.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; C | 2004 |
5-aminosalicylic acid given in the remission stage of colitis suppresses colitis-associated cancer in a mouse colitis model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; Colitis; Colitis, Ulcerative; Disease | 2007 |