mesalamine has been researched along with Adverse Drug Event in 17 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 10 (58.82) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Matthews, EJ | 1 |
| Kruhlak, NL | 1 |
| Weaver, JL | 1 |
| Benz, RD | 1 |
| Contrera, JF | 1 |
| Pedersen, JM | 1 |
| Matsson, P | 1 |
| Bergström, CA | 1 |
| Norinder, U | 1 |
| Hoogstraate, J | 1 |
| Artursson, P | 1 |
| Dhaneshwar, SS | 1 |
| Chail, M | 1 |
| Patil, M | 1 |
| Naqvi, S | 1 |
| Vadnerkar, G | 1 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 1 |
| Naessens, D | 1 |
| Cameron, C | 1 |
| Hoaglin, DC | 1 |
| Kruis, W | 1 |
| Neshta, V | 1 |
| Pesegova, M | 1 |
| Alekseeva, O | 1 |
| Andreev, P | 1 |
| Datsenko, O | 1 |
| Levchenko, O | 1 |
| Abdulkhakov, S | 1 |
| Lozynskyy, Y | 1 |
| Mostovoy, Y | 1 |
| Soloviev, K | 1 |
| Dorofeyev, AE | 1 |
| Vieth, M | 1 |
| Stiess, M | 1 |
| Greinwald, R | 1 |
| Mohrbacher, R | 1 |
| Siegmund, B | 1 |
| Jairath, V | 1 |
| Hokkanen, SRK | 1 |
| Guizzetti, L | 1 |
| Boxall, N | 1 |
| Campbell-Hill, S | 1 |
| Patel, H | 1 |
| Sharma, R | 1 |
| Rawal, RK | 1 |
| Gaba, T | 1 |
| Singla, N | 1 |
| Malhotra, M | 1 |
| Matharoo, S | 1 |
| Bhardwaj, TR | 1 |
| Ha, CY | 1 |
| Russo, L | 1 |
| Schneider, G | 1 |
| Gardiner, MH | 1 |
| Lanes, S | 1 |
| Streck, P | 1 |
| Rosen, S | 1 |
| Lang, A | 1 |
| Salomon, N | 1 |
| Wu, JC | 1 |
| Kopylov, U | 1 |
| Lahat, A | 1 |
| Har-Noy, O | 1 |
| Ching, JY | 1 |
| Cheong, PK | 1 |
| Avidan, B | 1 |
| Gamus, D | 1 |
| Kaimakliotis, I | 1 |
| Eliakim, R | 1 |
| Ng, SC | 1 |
| Ben-Horin, S | 1 |
| Sun, J | 1 |
| Shen, X | 1 |
| Dong, J | 1 |
| Wang, H | 1 |
| Zuo, L | 1 |
| Zhao, J | 1 |
| Zhu, W | 1 |
| Li, Y | 1 |
| Gong, J | 1 |
| Li, J | 1 |
| Casanova, MJ | 1 |
| Chaparro, M | 1 |
| García-Sánchez, V | 1 |
| Nantes, O | 1 |
| Leo, E | 1 |
| Rojas-Feria, M | 1 |
| Jauregui-Amezaga, A | 1 |
| García-López, S | 1 |
| Huguet, JM | 1 |
| Arguelles-Arias, F | 1 |
| Aicart, M | 1 |
| Marín-Jiménez, I | 1 |
| Gómez-García, M | 1 |
| Muñoz, F | 1 |
| Esteve, M | 1 |
| Bujanda, L | 1 |
| Cortés, X | 1 |
| Tosca, J | 1 |
| Pineda, JR | 1 |
| Mañosa, M | 1 |
| Llaó, J | 1 |
| Guardiola, J | 1 |
| Pérez-Martínez, I | 1 |
| Muñoz, C | 2 |
| González-Lama, Y | 1 |
| Hinojosa, J | 1 |
| Vázquez, JM | 1 |
| Martinez-Montiel, MP | 1 |
| Rodríguez, GE | 1 |
| Pajares, R | 1 |
| García-Sepulcre, MF | 1 |
| Hernández-Martínez, A | 1 |
| Pérez-Calle, JL | 1 |
| Beltrán, B | 1 |
| Busquets, D | 1 |
| Ramos, L | 1 |
| Bermejo, F | 1 |
| Barrio, J | 1 |
| Barreiro-de Acosta, M | 1 |
| Roncedo, O | 1 |
| Calvet, X | 1 |
| Hervías, D | 1 |
| Gomollón, F | 1 |
| Domínguez-Antonaya, M | 1 |
| Alcaín, G | 1 |
| Sicilia, B | 1 |
| Dueñas, C | 1 |
| Gutiérrez, A | 1 |
| Lorente-Poyatos, R | 1 |
| Domínguez, M | 1 |
| Khorrami, S | 1 |
| Taxonera, C | 1 |
| Rodríguez-Pérez, A | 1 |
| Ponferrada, A | 1 |
| Van Domselaar, M | 1 |
| Arias-Rivera, ML | 1 |
| Merino, O | 1 |
| Castro, E | 1 |
| Marrero, JM | 1 |
| Martín-Arranz, M | 1 |
| Botella, B | 1 |
| Fernández-Salazar, L | 1 |
| Monfort, D | 1 |
| Opio, V | 1 |
| García-Herola, A | 1 |
| Menacho, M | 1 |
| Ramírez-de la Piscina, P | 1 |
| Ceballos, D | 1 |
| Almela, P | 1 |
| Navarro-Llavat, M | 1 |
| Robles-Alonso, V | 1 |
| Vega-López, AB | 1 |
| Moraleja, I | 1 |
| Novella, MT | 1 |
| Castaño-Milla, C | 1 |
| Sánchez-Torres, A | 1 |
| Benítez, JM | 1 |
| Rodríguez, C | 1 |
| Castro, L | 1 |
| Garrido, E | 1 |
| Domènech, E | 1 |
| García-Planella, E | 1 |
| Gisbert, JP | 1 |
| Wenzl, HH | 1 |
| Hussar, DA | 1 |
| Perney, P | 1 |
| Berthier, E | 1 |
| Pageaux, GP | 1 |
| Hillaire-Buys, D | 1 |
| Roques, V | 1 |
| Fabbro-Peray, P | 1 |
| Melki, M | 1 |
| Hanslik, B | 1 |
| Bauret, P | 1 |
| Larrey, D | 1 |
| Blayac, JP | 1 |
| Blanc, F | 1 |
| Prantera, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-blind, Multicentre Study to Compare the Efficacy and Safety of Budesonide Versus Mesalazine Suppository Versus a Combination Therapy of Budesonide/Mesalazine Suppositories in Patients With Acute Ulcerative Proctitis[NCT01966783] | Phase 2 | 320 participants (Anticipated) | Interventional | 2013-09-30 | Completed | ||
| Randomized, Double-blind, Placebo-controlled Study to Evaluated the Efficacy of Combining Curcumin+5ASA Medication Versus 5ASA Medication Alone on Active Mild to Moderate Ulcerative Colitis Patients[NCT01320436] | Phase 3 | 50 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| Investigation of the Effects of Curcumin and Resveratrol Supplements Added to the Mediterranean Diet on Disease Severity and Inflammatory Biomarkers in Patients With Ulcerative Colitis[NCT05761327] | 45 participants (Anticipated) | Interventional | 2022-06-03 | Recruiting | |||
| Anti-TNF Discontinuation in Patients With Inflammatory Bowel Disease: Multicentre, Prospective, Randomized Clinical Trial and Economic Evaluation[NCT02994836] | Phase 4 | 139 participants (Actual) | Interventional | 2017-04-21 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for mesalamine and Adverse Drug Event
| Article | Year |
|---|---|
Medical management of inflammatory bowel disease in the elderly: balancing safety and efficacy.
Topics: Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Biotransformation; Comorbidity; Cost of Illnes | 2014 |
Diarrhea in chronic inflammatory bowel diseases.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidiarrheals; Bacterial Infections | 2012 |
Delayed-release Multi Matrix System (MMX) mesalazine in ulcerative colitis: a viewpoint by Cosimo Prantera.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Delayed-Action Preparations; Drug-Rela | 2007 |
3 trials available for mesalamine and Adverse Drug Event
| Article | Year |
|---|---|
Budesonide Suppositories Are Effective and Safe for Treating Acute Ulcerative Proctitis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Budesonide; Colitis, Ulcerative; Double-Blind Met | 2019 |
Curcumin in Combination With Mesalamine Induces Remission in Patients With Mild-to-Moderate Ulcerative Colitis in a Randomized Controlled Trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulc | 2015 |
Curcumin in Combination With Mesalamine Induces Remission in Patients With Mild-to-Moderate Ulcerative Colitis in a Randomized Controlled Trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulc | 2015 |
Curcumin in Combination With Mesalamine Induces Remission in Patients With Mild-to-Moderate Ulcerative Colitis in a Randomized Controlled Trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulc | 2015 |
Curcumin in Combination With Mesalamine Induces Remission in Patients With Mild-to-Moderate Ulcerative Colitis in a Randomized Controlled Trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulc | 2015 |
Tripterygium wilfordii Hook F as Maintenance Treatment for Crohn's Disease.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Crohn Disease; Dose-Response Relationship, Drug; Dru | 2015 |
11 other studies available for mesalamine and Adverse Drug Event
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Bi | 2008 |
Colon-specific mutual amide prodrugs of 4-aminosalicylic acid for their mitigating effect on experimental colitis in rats.
Topics: Aminosalicylic Acids; Animals; Colitis; Colon; Drug Delivery Systems; Drug Stability; Drug-Related S | 2009 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Network Meta-analysis of Ulcerative Colitis Pharmacotherapies: Carryover Effects From Induction and Bias of the Results.
Topics: Colitis, Ulcerative; Drug-Related Side Effects and Adverse Reactions; Humans; Mesalamine; Network Me | 2021 |
No increased risk of nephrotoxicity associated with 5-aminosalicylic acid in IBD: a population-based cohort and nested case-control study.
Topics: Aged; Aged, 80 and over; Case-Control Studies; Cohort Studies; Colitis, Ulcerative; Crohn Disease; D | 2019 |
Design, synthesis and ex vivo evaluation of colon-specific azo based prodrugs of anticancer agents.
Topics: Animals; Antineoplastic Agents; Azo Compounds; Cell Line, Tumor; Colon; Colonic Neoplasms; Drug Desi | 2013 |
Role of pharmacoepidemiology studies in addressing pharmacovigilance questions: a case example of pancreatitis risk among ulcerative colitis patients using mesalazine.
Topics: Acute Disease; Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Col | 2014 |
Evolution After Anti-TNF Discontinuation in Patients With Inflammatory Bowel Disease: A Multicenter Long-Term Follow-Up Study.
Topics: Adalimumab; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antirheumatic Agents; Colitis, | 2017 |
New drugs 2002, part 1.
Topics: Amides; Aminosalicylic Acids; Anti-Ulcer Agents; Antipsychotic Agents; Bimatoprost; Cloprostenol; Cy | 2002 |
Are drugs a risk factor of post-ERCP pancreatitis?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Cholangiopancreatography, Endoscopic Retro | 2003 |