mesalamine has been researched along with Adenomatous Polyps in 2 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Adenomatous Polyps: Benign neoplasms derived from glandular epithelium. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is an increased risk of colorectal cancer in patients with inflammatory bowel disease (IBD)." | 1.33 | Distal adenomatous polyps are rare in patients with inflammatory bowel disease. ( Dixon, A; Hart, A; Robinson, R; Wurm, P, 2006) |
| " To directly evaluate the ability of 5-ASA to suppress intestinal tumors, we studied several formulations of 5-ASA (free acid, sulfasalazine, and Pentasa) at multiple oral dosage levels [500, 2400, 4800, and 9600 parts/million (ppm)] in the adenomatous polyposis coli (Apc) mouse model of multiple intestinal neoplasia (Min)." | 1.30 | Evaluation of 5-aminosalicylic acid (5-ASA) for cancer chemoprevention: lack of efficacy against nascent adenomatous polyps in the Apc(Min) mouse. ( Gendler, SJ; Hirsch, RE; Leighton, JA; Morrow, JD; Ritland, SR; Weaver, AL, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dixon, A | 1 |
| Wurm, P | 1 |
| Hart, A | 1 |
| Robinson, R | 1 |
| Ritland, SR | 1 |
| Leighton, JA | 1 |
| Hirsch, RE | 1 |
| Morrow, JD | 1 |
| Weaver, AL | 1 |
| Gendler, SJ | 1 |
2 other studies available for mesalamine and Adenomatous Polyps
| Article | Year |
|---|---|
Distal adenomatous polyps are rare in patients with inflammatory bowel disease.
Topics: Adenomatous Polyps; Antimetabolites, Antineoplastic; Azathioprine; Case-Control Studies; Colorectal | 2006 |
Evaluation of 5-aminosalicylic acid (5-ASA) for cancer chemoprevention: lack of efficacy against nascent adenomatous polyps in the Apc(Min) mouse.
Topics: Adenomatous Polyps; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Chemo | 1999 |