mesalamine has been researched along with Adenoma, Basal Cell in 6 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate chemoprevention of colonic polyps with balsalazide, a 5-aminosalicylate prodrug." | 9.14 | Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled study. ( Gum, JR; Hayes, A; Johnson, LK; Kim, YS; McQuaid, KR; Sleisenger, MH; Terdiman, JP; Weinberg, VK, 2009) |
| "To investigate chemoprevention of colonic polyps with balsalazide, a 5-aminosalicylate prodrug." | 5.14 | Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled study. ( Gum, JR; Hayes, A; Johnson, LK; Kim, YS; McQuaid, KR; Sleisenger, MH; Terdiman, JP; Weinberg, VK, 2009) |
| " Thus, a general recommendation for long-term use of 5-ASA solely for chemopreventive measures is not warranted." | 2.48 | The role of chemoprevention of colorectal cancer with 5-aminosalicylates in ulcerative colitis. ( Herfarth, H, 2012) |
| "Most colorectal cancers (CRC) arise sporadically from precursor lesions: colonic polyps." | 1.62 | 5-Aminosalicylic acid inhibits stem cell function in human adenoma-derived cells: implications for chemoprophylaxis in colorectal tumorigenesis. ( Chambers, AC; Collard, TJ; Creed, TJ; Dixon, SW; Greenhough, A; Legge, DN; Mortensson, EMH; Williams, AC, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Dixon, SW | 1 |
| Collard, TJ | 1 |
| Mortensson, EMH | 1 |
| Legge, DN | 1 |
| Chambers, AC | 1 |
| Greenhough, A | 1 |
| Creed, TJ | 1 |
| Williams, AC | 1 |
| MacFie, TS | 1 |
| Poulsom, R | 1 |
| Parker, A | 1 |
| Warnes, G | 1 |
| Boitsova, T | 1 |
| Nijhuis, A | 1 |
| Suraweera, N | 1 |
| Poehlmann, A | 1 |
| Szary, J | 1 |
| Feakins, R | 1 |
| Jeffery, R | 1 |
| Harper, RW | 1 |
| Jubb, AM | 1 |
| Lindsay, JO | 1 |
| Silver, A | 1 |
| Terdiman, JP | 1 |
| Johnson, LK | 1 |
| Kim, YS | 1 |
| Sleisenger, MH | 1 |
| Gum, JR | 1 |
| Hayes, A | 1 |
| Weinberg, VK | 1 |
| McQuaid, KR | 1 |
| Kisiel, JB | 1 |
| Loftus, EV | 1 |
| Harmsen, WS | 1 |
| Zinsmeister, AR | 1 |
| Sandborn, WJ | 1 |
| Munding, J | 1 |
| Ziebarth, W | 1 |
| Pox, CP | 1 |
| Ladigan, S | 1 |
| Reiser, M | 1 |
| Hüppe, D | 1 |
| Brand, L | 1 |
| Schmiegel, W | 1 |
| Tannapfel, A | 1 |
| Reinacher-Schick, AC | 1 |
| Herfarth, H | 1 |
1 review available for mesalamine and Adenoma, Basal Cell
| Article | Year |
|---|---|
The role of chemoprevention of colorectal cancer with 5-aminosalicylates in ulcerative colitis.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colo | 2012 |
1 trial available for mesalamine and Adenoma, Basal Cell
| Article | Year |
|---|---|
Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled study.
Topics: Adenoma; Aged; Apoptosis; Colon, Sigmoid; Colonic Neoplasms; Colonic Polyps; Double-Blind Method; Ga | 2009 |
4 other studies available for mesalamine and Adenoma, Basal Cell
| Article | Year |
|---|---|
5-Aminosalicylic acid inhibits stem cell function in human adenoma-derived cells: implications for chemoprophylaxis in colorectal tumorigenesis.
Topics: Adenoma; Carcinogenesis; Carcinoma; Cell Line, Tumor; Cell Transformation, Neoplastic; Chemopreventi | 2021 |
DUOX2 and DUOXA2 form the predominant enzyme system capable of producing the reactive oxygen species H2O2 in active ulcerative colitis and are modulated by 5-aminosalicylic acid.
Topics: Adenoma; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cells, Cultured; Colitis, Ulcer | 2014 |
Outcome of sporadic adenomas and adenoma-like dysplasia in patients with ulcerative colitis undergoing polypectomy.
Topics: Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Cell T | 2012 |
The influence of 5-aminosalicylic acid on the progression of colorectal adenomas via the β-catenin signaling pathway.
Topics: Adenoma; beta Catenin; Cadherins; Cell Line, Tumor; Colitis, Ulcerative; Colorectal Neoplasms; Cycli | 2012 |