mesalamine has been researched along with Adenocarcinoma, Basal Cell in 14 studies
Mesalamine: An anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE. (From Martindale, The Extra Pharmacopoeia, 30th ed)
mesalamine : A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Thus, a general recommendation for long-term use of 5-ASA solely for chemopreventive measures is not warranted." | 2.48 | The role of chemoprevention of colorectal cancer with 5-aminosalicylates in ulcerative colitis. ( Herfarth, H, 2012) |
| " Therapeutic success of mesalazine may be optimized by a combination of high dose and low frequency of dosage to improve compliance." | 2.43 | Indications for 5-aminosalicylate in inflammatory bowel disease: is the body of evidence complete? ( Mulder, CJ; van Bodegraven, AA, 2006) |
| "Although colorectal cancer (CRC), complicating ulcerative colitis and Crohn's disease, only accounts for 1-2% of all cases of CRC in the general population, it is considered a serious complication of the disease and accounts for approximately 15% of all deaths in inflammatory bowel disease (IBD) patients." | 2.42 | Review article: the incidence and prevalence of colorectal cancer in inflammatory bowel disease. ( Munkholm, P, 2003) |
| "The use of immunosuppressants for the treatment of nephrotic syndrome might affect the development of rectal carcinoma." | 1.43 | Ulcerative colitis associated with nephrotic syndrome after treatment with mesalazine developed into rectal carcinoma: a case study. ( Koketsu, S; Kubota, Y; Noie, T; Okuyama, T; Ono, Y; Oya, M; Sameshima, S, 2016) |
| "To investigate the effects of 5-aminosalicylic acid (5-ASA) in combination with nimesulide on the proliferation of HT-29 colon carcinoma cells and its potential mechanisms." | 1.34 | 5-aminosalicylic acid in combination with nimesulide inhibits proliferation of colon carcinoma cells in vitro. ( Fang, HM; Ma, WJ; Mei, Q; Xu, JM, 2007) |
| "An increased incidence of colonic cancer is associated with chronic inflammatory bowel disease." | 1.28 | The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model. ( Crouch, R; Davis, AE; Patterson, F, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 6 (42.86) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Moreno Moraleda, I | 1 |
| Lázaro Sáez, M | 1 |
| Diéguez Castillo, C | 1 |
| Hernández Martínez, Á | 1 |
| Nieminen, U | 1 |
| Jussila, A | 1 |
| Nordling, S | 1 |
| Mustonen, H | 1 |
| Färkkilä, MA | 1 |
| Andersson, P | 1 |
| Norblad, R | 1 |
| Söderholm, JD | 1 |
| Myrelid, P | 1 |
| Chapman, CG | 1 |
| Rubin, DT | 1 |
| Sameshima, S | 1 |
| Koketsu, S | 1 |
| Okuyama, T | 1 |
| Kubota, Y | 1 |
| Ono, Y | 1 |
| Noie, T | 1 |
| Oya, M | 1 |
| Bazuro, GE | 1 |
| Torino, F | 1 |
| Gasparini, G | 1 |
| Capurso, L | 1 |
| Qualtrough, D | 1 |
| Smallwood, K | 1 |
| Littlejohns, D | 1 |
| Pignatelli, M | 1 |
| Herfarth, H | 1 |
| Munkholm, P | 1 |
| Monteleone, G | 1 |
| Franchi, L | 1 |
| Fina, D | 1 |
| Caruso, R | 1 |
| Vavassori, P | 1 |
| Monteleone, I | 1 |
| Calabrese, E | 1 |
| Naccari, GC | 1 |
| Bellinvia, S | 1 |
| Testi, R | 1 |
| Pallone, F | 1 |
| Kronberger, IE | 1 |
| Graziadei, IW | 1 |
| Vogel, W | 1 |
| van Bodegraven, AA | 1 |
| Mulder, CJ | 1 |
| Fang, HM | 1 |
| Mei, Q | 1 |
| Xu, JM | 1 |
| Ma, WJ | 1 |
| Davis, AE | 1 |
| Patterson, F | 1 |
| Crouch, R | 1 |
6 reviews available for mesalamine and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
The potential for medical therapy to reduce the risk of colorectal cancer and optimize surveillance in inflammatory bowel disease.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Cholagogues and Choleretics; | 2014 |
Chemoprevention in gastrointestinal adenocarcinoma: for few but not for all?
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colorectal Neoplasms; ErbB Recepto | 2008 |
The role of chemoprevention of colorectal cancer with 5-aminosalicylates in ulcerative colitis.
Topics: Adenocarcinoma; Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Colo | 2012 |
Review article: the incidence and prevalence of colorectal cancer in inflammatory bowel disease.
Topics: Adenocarcinoma; Age of Onset; Anti-Inflammatory Agents, Non-Steroidal; Colorectal Neoplasms; Humans; | 2003 |
Small bowel adenocarcinoma in Crohn's disease: a case report and review of literature.
Topics: Adenocarcinoma; Adult; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Crohn Disease; Humans; | 2006 |
Indications for 5-aminosalicylate in inflammatory bowel disease: is the body of evidence complete?
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Colonic Neoplasms; Humans; Inflammatory Bow | 2006 |
8 other studies available for mesalamine and Adenocarcinoma, Basal Cell
| Article | Year |
|---|---|
Inflammatory bowel disease and inherited colorectal cancer: Is there a genetic link?
Topics: Adenocarcinoma; Adult; Age of Onset; Anti-Inflammatory Agents; Azathioprine; Breast Neoplasms; Colit | 2021 |
Inflammation and disease duration have a cumulative effect on the risk of dysplasia and carcinoma in IBD: a case-control observational study based on registry data.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Ileorectal anastomosis in comparison with ileal pouch anal anastomosis in reconstructive surgery for ulcerative colitis--a single institution experience.
Topics: Abdominal Neoplasms; Adenocarcinoma; Adolescent; Adrenal Cortex Hormones; Adult; Anastomosis, Surgic | 2014 |
Ulcerative colitis associated with nephrotic syndrome after treatment with mesalazine developed into rectal carcinoma: a case study.
Topics: Adenocarcinoma; Adolescent; Antineoplastic Agents; Colitis, Ulcerative; Colonoscopy; Humans; Lymphat | 2016 |
The actin-bundling protein fascin is overexpressed in inflammatory bowel disease and may be important in tissue repair.
Topics: Actins; Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Butyrates; Carrier Proteins; Cell L | 2011 |
Silencing of SH-PTP2 defines a crucial role in the inactivation of epidermal growth factor receptor by 5-aminosalicylic acid in colon cancer cells.
Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Colorectal Neopl | 2006 |
5-aminosalicylic acid in combination with nimesulide inhibits proliferation of colon carcinoma cells in vitro.
Topics: Adenocarcinoma; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Proliferation; Colonic Neop | 2007 |
The effect of therapeutic drugs used in inflammatory bowel disease on the incidence and growth of colonic cancer in the dimethylhydrazine rat model.
Topics: Adenocarcinoma; Aminosalicylic Acids; Animals; Cocarcinogenesis; Colonic Neoplasms; Dimethylhydrazin | 1992 |