merulin-a has been researched along with Breast-Neoplasms* in 1 studies
1 other study(ies) available for merulin-a and Breast-Neoplasms
Article | Year |
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Cytotoxic nor-chamigrane and chamigrane endoperoxides from a basidiomycetous fungus.
A new nor-chamigrane endoperoxide, merulin A (1), and two new chamigrane endoperoxides, merulins B and C (2, 3), were isolated from the culture broth extract of an endophytic fungus of Xylocarpus granatum. Their structures were elucidated on the basis of spectroscopic, mainly NMR and MS, data. X-ray crystallographic analysis confirmed the structure of 1. Compounds 1 and 3 displayed significant cytotoxicity against human breast (BT474) and colon (SW620) cancer cell lines. Topics: Antineoplastic Agents; Basidiomycota; Breast Neoplasms; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Female; Humans; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Peroxides | 2010 |