mersalyl has been researched along with Syndrome* in 1 studies
1 other study(ies) available for mersalyl and Syndrome
Article | Year |
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[The receptor of adenosine-dephosphate on the human platelet membrane (author's translation)].
The binding of 14C-ADP on the isolated platelet membrane is a saturable and reversible phenomenon which seems to implicate a protein only partially solubilised by Triton X-100. The binding is strongly reduced by mersalyl, which is known to inhibit the ATPase activity of the thrombosthenin i.e. the platelet contractile protein; this protein could be involved in the mechanism of binding of ADP on the platelet membrane. Platelets not aggregated by ADP from patients with Glanzmann's thrombasthenia, have a normal binding of 14C-ADP which is also strongly reduced by mersalyl. Topics: Adenosine Diphosphate; Blood Platelets; Blood Proteins; Carbon Radioisotopes; Cell Membrane; Humans; Kinetics; Mersalyl; Ouabain; Polyethylene Glycols; Purpura, Thrombocytopenic; Receptors, Drug; Solubility; Syndrome | 1976 |