meropenem and Skin-Ulcer

Our report concerns a 24-year-old man with a chronic exsudative skin lesion after a journey to Southeast Asia. The diagnosis of melioidosis was made by the identification of Burkholderia pseudomallei from the ichor. The diagnosis was confirmed by polymerase change reaction. The patient was treated with meropenem i. v. for about 10 days and with trimethoprim/sulfamethoxazole for the following 12 weeks. Melioidosis is an endemic disease in Southeast Asia and North Australia which in some cases can run a severe course and can have a high fatality rate. The relevance of melioidosis becomes more important against the background of the increasing global movement of travelers and migration.

Topics: Anti-Bacterial Agents; Asia, Southeastern; Burkholderia pseudomallei; Chronic Disease; Humans; Male; Melioidosis; Meropenem; Skin Ulcer; Thienamycins; Travel-Related Illness; Young Adult

Topics: Amikacin; Facial Dermatoses; Fatal Outcome; Female; Gangrene; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Meropenem; Necrosis; Neutropenia; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Skin Diseases, Bacterial; Skin Ulcer; Thienamycins

Cutaneous infection develops because of environmental and local factors, host immunity, and organism adherence and virulence. The authors report a case of exuberant cutaneous ulcers on the buttocks of a diabetic patient. Microbiologic examination allowed the identification of Klebsiella pneumoniae and complete resolution was achieved with the appropriate antibiotic.

Topics: Aged, 80 and over; Anti-Bacterial Agents; Buttocks; Diabetes Complications; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Skin Diseases, Bacterial; Skin Ulcer; Thienamycins