meropenem and Nephrotic-Syndrome

Bacillus cereus (B. cereus) is a Gram-positive rod that is widely distributed in the environment and can be a cause of food poisoning. We herein present a case of B. cereus necrotizing pneumonia in a patient with nephrotic syndrome under corticosteroid treatment after developing transient gastroenteritis symptoms. B. cereus was isolated from bronchial lavage fluid and transbronchial biopsy specimens. A multiplex polymerase chain reaction analysis of the toxin genes revealed a strain possessing enterotoxicity. The patient recovered after one week of intravenous meropenem followed by a combination of oral moxifloxacin and clindamycin. B. cereus is a pathogen that causes necrotizing pneumonia in immunocompromised hosts.

Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Aza Compounds; Bacillus cereus; Biopsy, Needle; Bronchoalveolar Lavage Fluid; Clindamycin; Drug Therapy, Combination; Fluoroquinolones; Follow-Up Studies; Gram-Positive Bacterial Infections; Humans; Immunocompromised Host; Immunohistochemistry; Male; Meropenem; Moxifloxacin; Necrosis; Nephrotic Syndrome; Pneumonia, Bacterial; Quinolines; Radiography, Thoracic; Risk Assessment; Severity of Illness Index; Thienamycins; Tomography, X-Ray Computed; Treatment Outcome