meropenem and Empyema--Pleural

Infections caused by fusobacteria have a wide clinical spectrum, and in certain patients, they can lead to severe systemic illness. We report the case of an immunocompromised young woman who presented with severe pneumonia complicated by parapneumonic pleural effusion, despite wide-spectrum antibiotic treatment.

Topics: Adult; Anti-Bacterial Agents; Diagnosis, Differential; Empyema, Pleural; Female; Fusobacterium Infections; Fusobacterium necrophorum; Humans; Immunocompetence; Lemierre Syndrome; Meropenem; Pleural Effusion; Pneumonia; Treatment Outcome

Empyema secondary to foreign body aspiration is rare in adults. We present a case of empyema in a 77-year-old male patient related to a remote aspiration event during a dental procedure. A CT of the chest and bronchoscopy confirmed that a metallic foreign body was located within the right lower lobe bronchus. His pleural fluid culture revealed

Topics: Aged; Anti-Bacterial Agents; Bronchoscopy; Empyema, Pleural; Foreign Bodies; Gram-Negative Bacterial Infections; Humans; Levofloxacin; Lung; Male; Meropenem; Respiratory Aspiration; Sphingomonas; Thienamycins; Tomography, X-Ray Computed

A 24-year-old man presented with fever and pleural effusion predominantly containing lymphocytes. Cultures of the pleural effusion and blood revealed Campylobacter fetus, and laboratory studies showed a low serum level of immunoglobulin. The patient was diagnosed with C. fetus pleuritis, bacteremia and primary hypogammaglobulinemia, and subsequent treatment with meropenem and immunoglobulin improved his condition. Although the underlying cause of the primary hypogammaglobulinemia remains unclear, the patient's status improved under immunoglobulin replacement therapy. C. fetus pleuritis is a rare infectious disease usually observed in immunocompromised hosts. We herein describe the first report of C. fetus pleuritis in a young adult with primary hypogammaglobulinemia.

Topics: Agammaglobulinemia; Bacteremia; Campylobacter fetus; Campylobacter Infections; Empyema, Pleural; Humans; Immunization, Passive; Immunocompromised Host; Lung; Male; Meropenem; Pleural Effusion; Pleurisy; Radiography; Thienamycins; Young Adult