meropenem and Agammaglobulinemia

meropenem has been researched along with Agammaglobulinemia* in 3 studies

Reviews

1 review(s) available for meropenem and Agammaglobulinemia

ArticleYear
Campylobacter jejuni bacteremia and Helicobacter pylori in a patient with X-linked agammaglobulinemia.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2010, Volume: 29, Issue:11

    We describe a 15-year-old patient with X-linked agammaglobulinemia who developed malabsorption and bacteremia due to infection of Helicobacter pylori and Campylobacter jejuni. The Campylobacter bacteremia was only recognized after subculturing of blood culture bottles that failed to signal in the automated system. After 2 weeks of treatment with meropenem and erythromycin for 4 weeks, the patient developed a relapse of bacteremia 10 months later with a high level erythromycin resistant C. jejuni. Sequencing revealed an A2058C mutation in the 23 S rRNA gene associated with this resistance. Treatment with doxycycline for 4 weeks finally resulted in complete eradication. This case report illustrates the importance for physicians to use adapted culture methods and adequate prolonged therapy in patients with an immunodeficiency. A summary of published case reports and series of patients with hypogammaglobulinemia or agammaglobulinemia with Campylobacter or Helicobacter bacteremia is given.

    Topics: Adolescent; Agammaglobulinemia; Anti-Bacterial Agents; Bacteremia; Campylobacter Infections; Campylobacter jejuni; Doxycycline; Drug Resistance, Bacterial; Erythromycin; Genetic Diseases, X-Linked; Helicobacter Infections; Helicobacter pylori; Humans; Immunocompromised Host; Malabsorption Syndromes; Male; Meropenem; Mutation; Recurrence; Thienamycins

2010

Other Studies

2 other study(ies) available for meropenem and Agammaglobulinemia

ArticleYear
Campylobacter fetus bacteremia with purulent pleurisy in a young adult with primary hypogammaglobulinemia.
    Internal medicine (Tokyo, Japan), 2014, Volume: 53, Issue:11

    A 24-year-old man presented with fever and pleural effusion predominantly containing lymphocytes. Cultures of the pleural effusion and blood revealed Campylobacter fetus, and laboratory studies showed a low serum level of immunoglobulin. The patient was diagnosed with C. fetus pleuritis, bacteremia and primary hypogammaglobulinemia, and subsequent treatment with meropenem and immunoglobulin improved his condition. Although the underlying cause of the primary hypogammaglobulinemia remains unclear, the patient's status improved under immunoglobulin replacement therapy. C. fetus pleuritis is a rare infectious disease usually observed in immunocompromised hosts. We herein describe the first report of C. fetus pleuritis in a young adult with primary hypogammaglobulinemia.

    Topics: Agammaglobulinemia; Bacteremia; Campylobacter fetus; Campylobacter Infections; Empyema, Pleural; Humans; Immunization, Passive; Immunocompromised Host; Lung; Male; Meropenem; Pleural Effusion; Pleurisy; Radiography; Thienamycins; Young Adult

2014
Relapsing Campylobacter coli bacteremia with reactive arthritis in a patient with X-linked agammaglobulinemia.
    Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:9

    A patient genetically diagnosed with X-linked agammaglobulinemia repeatedly developed bacteremia due to Campylobacter coli (C. coli) for one year and seven months in spite of immunoglobulin replacement therapy. Throughout the clinical course, C. coli with identical genetic patterns was repeatedly isolated from both blood and stool cultures, thus indicating that the patient had latent intestinal infection. The bacteremia was always accompanied by reactive arthritis. Since the immunoglobulin level was extremely low with severe B cell deficiency, the reactive arthritis must have been induced in a humoral immunity-independent manner. Adding oral minocycline following intravenous meropenem was very effective; the stool cultures became negative and the patient has been well for more than one year without relapse of bacteremia.

    Topics: Administration, Oral; Adult; Agammaglobulinemia; Anti-Bacterial Agents; Arthritis, Reactive; Bacteremia; Campylobacter coli; Campylobacter Infections; Chromosomes, Human, X; Feces; Genetic Linkage; Humans; Injections, Intravenous; Intestinal Diseases; Male; Meropenem; Minocycline; Recurrence; Thienamycins; Treatment Outcome

2007
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