mercaptopurine and Oral-Ulcer

mercaptopurine has been researched along with Oral-Ulcer* in 1 studies

Other Studies

1 other study(ies) available for mercaptopurine and Oral-Ulcer

ArticleYear
[Successful primary infliximab treatment of orofacial Crohn's disease without gastrointestinal manifestation].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2012, Jun-25, Volume: 59, Issue:6

    Crohn's disease is a chronic inflammatory bowel disease that can involve the whole gastrointestinal tract. The orofacial manifestation of Crohn's disease, which is rare, can develop irrespective of intestinal involvement. These orofacial lesions are often misdiagnosed as simple oral ulcers. Corticosteroids are the mainstay of therapy for orofacial Crohn's disease. However, infliximab, the chimeric monoclonal antibody to tumor necrosis factor-a, is now considered as a primary treatment because of the disease's relatively high rate of steroid resistance. We present a case of deep oral ulcer and periorbital swelling in a 65-year-old woman. She was diagnosed with intestinal Crohn's disease 7 years ago, which was in remission after treatment with an immunosuppressive agent (azathioprine). The patient was given the diagnosed with orofacial Crohn's disease and successfully treated with infliximab.

    Topics: Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Crohn Disease; Female; Gastrointestinal Diseases; Humans; Immunosuppressive Agents; Infliximab; Mercaptopurine; Oral Ulcer

2012