mercaptopurine and Hepatitis

mercaptopurine has been researched along with Hepatitis* in 65 studies

Reviews

11 review(s) available for mercaptopurine and Hepatitis

Article	Year
[Therapy of chronic progessive hepatitis]. La Clinica terapeutica, 1980, Aug-31, Volume: 94, Issue:4 Topics: Adrenal Cortex Hormones; Aminoimidazole Carboxamide; Azathioprine; Chlorambucil; Chronic Disease; Hepatitis; Humans; Mercaptopurine; Penicillamine; Succinates; Vitamins	1980
Assessment of autoantigenic activity of hepatic tissue components. Gastroenterology, 1976, Volume: 71, Issue:1 Topics: Alcoholism; Animals; Antigens; Autoantigens; Autoimmune Diseases; Cell Migration Inhibition; Hepatitis; Humans; Immunity, Cellular; Leukocytes; Liver; Macrophage Migration-Inhibitory Factors; Mercaptopurine	1976
[Immunodepressants in chronic liver diseases (a review of the literature and the authors' own data)]. Terapevticheskii arkhiv, 1976, Volume: 48, Issue:3 Topics: Azathioprine; B-Lymphocytes; Chronic Disease; Denmark; Drug Evaluation; Female; Glucocorticoids; Hepatitis; Humans; Immunity, Cellular; Immunosuppressive Agents; Liver Cirrhosis; Liver Diseases; Male; Mercaptopurine; Placebos; T-Lymphocytes	1976
An approach to the use of immunosuppressive drugs in nonmalignant diseases. The Journal of allergy and clinical immunology, 1973, Volume: 52, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chlorambucil; Cyclophosphamide; Granulomatosis with Polyangiitis; Hepatitis; Humans; Immunosuppressive Agents; Liver Cirrhosis; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Mice; Mice, Inbred NZB; Multiple Sclerosis; Nephritis; Nephrosis; Nitrogen Mustard Compounds; Penicillins; Psoriasis; Uveitis, Anterior	1973
Cytotoxic drugs in treatment of nonmalignant diseases. Annals of internal medicine, 1972, Volume: 76, Issue:4 Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Colitis, Ulcerative; Crohn Disease; Cyclophosphamide; Granulomatosis with Polyangiitis; Hepatitis; Humans; Immune Complex Diseases; Immunosuppressive Agents; Infections; Liver Cirrhosis, Biliary; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Nephrotic Syndrome; Ophthalmia, Sympathetic; Psoriasis; Thioguanine; Uveitis	1972
Immunosuppressive therapy. 1. The New England journal of medicine, 1972, Aug-03, Volume: 287, Issue:5 Topics: Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Antimetabolites; Arthritis, Rheumatoid; Azathioprine; Blood Coagulation Disorders; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Cyclophosphamide; Dermatomyositis; Factor VIII; Hepatitis; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Prednisolone; Purpura, Thrombocytopenic; Scleroderma, Systemic	1972
Treatment of chronic hepatitis. Progress in liver diseases, 1972, Volume: 4 Topics: Adrenal Cortex Hormones; Aspartate Aminotransferases; Azathioprine; Blood Proteins; Chronic Disease; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Function Tests; Mercaptopurine; Prednisone; Rest; Serum Albumin; Serum Globulins; Time Factors	1972
Therapeutic considerations in selected forms of acute and chronic liver disease. The Medical clinics of North America, 1971, Volume: 55, Issue:2 Topics: Acute Disease; Age Factors; Alcoholism; Azathioprine; Chemical and Drug Induced Liver Injury; Chronic Disease; Cortisone; Diet Therapy; Exchange Transfusion, Whole Blood; Halothane; Hepatic Encephalopathy; Hepatitis; Hepatitis A; Hepatitis B; Hepatitis B Antigens; Hospitalization; Humans; Liver Diseases; Liver Function Tests; Malabsorption Syndromes; Mercaptopurine; Prednisone; Prognosis; Pruritus	1971
Active chronic hepatitis. The American journal of medicine, 1970, Volume: 48, Issue:4 Topics: Adrenal Cortex Hormones; Azathioprine; Chronic Disease; Diagnosis, Differential; False Positive Reactions; Hepatitis; Hepatitis A; Humans; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Mercaptopurine	1970
[Glucocorticoids and immunosuppressive agents in liver diseases]. Revista espanola de las enfermedades del aparato digestivo, 1970, Dec-01, Volume: 32, Issue:7 Topics: Acute Disease; Glucocorticoids; Hepatitis; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis; Liver Diseases; Mercaptopurine; Prednisolone; Prednisone	1970
[Immunopathology of chronic hepatitis and results of therapy with cytostatics]. Deutsches medizinisches Journal, 1969, Volume: 20, Issue:15 Topics: Animals; Autoantibodies; Azathioprine; Carbon Tetrachloride; Cell Membrane Permeability; Cell Nucleus; Chronic Disease; Hepatitis; Humans; Immunosuppressive Agents; Liver; Lymphocytes; Mercaptopurine; Microscopy, Electron; Mitochondria, Liver; Rats	1969

Trials

2 trial(s) available for mercaptopurine and Hepatitis

Article	Year
Pretreatment liver biopsy in 20 children with histiocytosis X: a clinicopathologic correlation. Medical and pediatric oncology, 1990, Volume: 18, Issue:2 Liver biopsies were done on 20 patients with histiocytosis X (HX) as part of pretreatment evaluation prior to entry on two Childrens Cancer Study Group protocols. Seventeen patients had hepatomegaly, and seven had one or more abnormal laboratory parameters using Lahey's criteria for liver dysfunction. Nineteen of 20 specimens showed various abnormalities of the portal triads. A single biopsy revealed normal liver. Among the changes were triaditis, bile duct proliferation, variable fibrosis with histiocytic infiltrates, and cirrhosis. One patient had typical granulomas of HX within the liver parenchyma in addition to portal triaditis. Patients with larger livers and dysfunction tended to show more marked histologic abnormalities in the portal triads. However, correlations among liver size, function, and pathology showed considerable overlap. Early death among these patients was more likely to be associated with progressive HX in other sites and/or infection. Death from cirrhosis and liver failure per se occurred in one patient 4 years after initial biopsy, but five other children had evidence of cirrhosis on biopsy or at autopsy. The majority of patients with triaditis initially did not have clinical evidence of progressive liver disease although four expired with other manifestations of HX or infection. Conversely, patients showing fibrohistiocytic changes or cirrhosis initially were likely to have continuing or progressive liver disease. Although the liver histology was not diagnostic of HX, the types of portal changes usually predicted the subsequent course of liver disease. Topics: Biopsy, Needle; Child; Child, Preschool; Cyclophosphamide; Follow-Up Studies; Hepatitis; Hepatomegaly; Histiocytosis, Langerhans-Cell; Humans; Infant; Liver; Liver Cirrhosis; Liver Function Tests; Mercaptopurine; Methotrexate; Multicenter Studies as Topic; Prednisone; Vinblastine	1990
Immunosuppressive therapy. 1. The New England journal of medicine, 1972, Aug-03, Volume: 287, Issue:5 Topics: Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Antimetabolites; Arthritis, Rheumatoid; Azathioprine; Blood Coagulation Disorders; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Cyclophosphamide; Dermatomyositis; Factor VIII; Hepatitis; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Prednisolone; Purpura, Thrombocytopenic; Scleroderma, Systemic	1972

Article

Year

Pretreatment liver biopsy in 20 children with histiocytosis X: a clinicopathologic correlation.

Medical and pediatric oncology, 1990, Volume: 18, Issue:2

Liver biopsies were done on 20 patients with histiocytosis X (HX) as part of pretreatment evaluation prior to entry on two Childrens Cancer Study Group protocols. Seventeen patients had hepatomegaly, and seven had one or more abnormal laboratory parameters using Lahey's criteria for liver dysfunction. Nineteen of 20 specimens showed various abnormalities of the portal triads. A single biopsy revealed normal liver. Among the changes were triaditis, bile duct proliferation, variable fibrosis with histiocytic infiltrates, and cirrhosis. One patient had typical granulomas of HX within the liver parenchyma in addition to portal triaditis. Patients with larger livers and dysfunction tended to show more marked histologic abnormalities in the portal triads. However, correlations among liver size, function, and pathology showed considerable overlap. Early death among these patients was more likely to be associated with progressive HX in other sites and/or infection. Death from cirrhosis and liver failure per se occurred in one patient 4 years after initial biopsy, but five other children had evidence of cirrhosis on biopsy or at autopsy. The majority of patients with triaditis initially did not have clinical evidence of progressive liver disease although four expired with other manifestations of HX or infection. Conversely, patients showing fibrohistiocytic changes or cirrhosis initially were likely to have continuing or progressive liver disease. Although the liver histology was not diagnostic of HX, the types of portal changes usually predicted the subsequent course of liver disease.

Topics: Biopsy, Needle; Child; Child, Preschool; Cyclophosphamide; Follow-Up Studies; Hepatitis; Hepatomegaly; Histiocytosis, Langerhans-Cell; Humans; Infant; Liver; Liver Cirrhosis; Liver Function Tests; Mercaptopurine; Methotrexate; Multicenter Studies as Topic; Prednisone; Vinblastine

1990

Immunosuppressive therapy. 1.

The New England journal of medicine, 1972, Aug-03, Volume: 287, Issue:5

Topics: Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Antimetabolites; Arthritis, Rheumatoid; Azathioprine; Blood Coagulation Disorders; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Cyclophosphamide; Dermatomyositis; Factor VIII; Hepatitis; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Prednisolone; Purpura, Thrombocytopenic; Scleroderma, Systemic

1972

Other Studies

53 other study(ies) available for mercaptopurine and Hepatitis

Article	Year
The successful treatment of autoimmune hepatitis with 6-mercaptopurine after failure with azathioprine. Gastroenterology, 1996, Volume: 110, Issue:1 Although the treatment of choice for autoimmune hepatitis is glucocorticoids, their side effects make long-term use undesirable. Therefore, other immunosuppressive agents have been used to replace glucocorticoids in the long-term treatment of autoimmune hepatitis, including azathioprine, a purine analogue. It is derived from 6-mercaptopurine, and these two drugs are often used interchangeably. However, these drugs have different toxicity profiles and may have clinically relevant differences in immunosuppressive activity in individual patients. We report 3 patients with autoimmune hepatitis who either could not tolerate or failed to improve on azathioprine but responded well to 6-mercaptopurine. Topics: Adolescent; Adult; Autoimmune Diseases; Azathioprine; Female; Hepatitis; Humans; Male; Mercaptopurine; Remission Induction	1996
Azathioprine and 6-mercaptopurine and autoimmune hepatitis. Gastroenterology, 1996, Volume: 110, Issue:6 Topics: Autoimmune Diseases; Azathioprine; Hepatitis; Humans; Mercaptopurine	1996
[Chronic hepatitis. Treatment]. Revista de medicina de la Universidad de Navarra, 1979, Volume: 23, Issue:4 Topics: Azathioprine; Drug Therapy, Combination; Hepatitis; Humans; Mercaptopurine; Prednisone	1979
[Chronic hepatitis: diagnostic and therapeutic problems]. Minerva medica, 1975, Apr-25, Volume: 66, Issue:31 The morphological criteria for diagnosing chronic hepatitis are discussed and criticised. A classification closer to clinical reality than that of De Groote et al 1968 is then proposed. Personal experience in differential laboratory diagnosis between the various forms of chronic hepatitis by means of comparative evaluation of an enzymogram and the measurement of certain proteins in the serum is then reported. Case examples are given to emphasise the possibilities of the immunological approach to the problem of active chronic hepatitis. Finally, the cardinal points of therapy are reviewed. Topics: Adult; Anti-Inflammatory Agents; Antibodies; Azathioprine; Blood Proteins; Clinical Enzyme Tests; Drug Therapy, Combination; Female; Fluorescent Antibody Technique; Hepatitis; Hepatitis B Antigens; Humans; Immunodiffusion; Immunoglobulins; Immunosuppressive Agents; Liver Cirrhosis; Liver Function Tests; Male; Mercaptopurine; Middle Aged; Prednisone	1975
Results of immunosuppressive treatment: Prognosis in chronic active hepatitis. Acta hepato-gastroenterologica, 1975, Volume: 22, Issue:4 A series of 21 patients with active chronic hepatit diagnosed on the basis of clinical, biochemical and histological criteria, were treated by immunosuppressive cure--a combination of Prednison or Triamcinolon with 6-Mercaptopurin. The cure lasted for at least 12 months and attempts as its interruption usually brought about exacerbation of activity requiring further treatment reaching the total of more than 3 years, in some cases lasting for all the followed period of 7 years. There were no significant side effects requiring interruption. Immunosuppressive treatment remarkably improved biochemical indicators, particularly significant was the decrease in SGPT activity and hypergammaglobulinemia. The results were likewise good in HB-Ag positive patients, 8 of which are included in the series. The prognosis of chronic active hepatitis undergoing immunosuppressive treatment was mathematically estimated. Using the mathematical solution of biological problems the authors arrived at the probable survival of 5.5 to 6.5 years for their series of patients. Topics: Chronic Disease; Drug Therapy, Combination; Follow-Up Studies; Hepatitis; Hepatitis B; Humans; Immunosuppressive Agents; Liver Function Tests; Mercaptopurine; Prednisone; Triamcinolone	1975
[Role of immunodepressants in the treatment of chronic active (lupoid) hepatitis]. Vestnik Akademii meditsinskikh nauk SSSR, 1975, Issue:6 Topics: Adrenal Cortex Hormones; Antilymphocyte Serum; Azathioprine; Chronic Disease; Drug Therapy, Combination; Female; Hepatitis; Humans; Immunosuppressive Agents; Male; Mercaptopurine	1975
Letter: The T lymphocyte and hepatitis. Lancet (London, England), 1974, Oct-26, Volume: 2, Issue:7887 Topics: Adrenal Cortex Hormones; Hepatitis; Humans; Immunity, Cellular; Immunity, Maternally-Acquired; Mercaptopurine; T-Lymphocytes	1974
[The treatment of chronic hepatitis (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1974, Mar-29, Volume: 116, Issue:13 Topics: Adrenal Cortex Hormones; Antimetabolites; Azathioprine; Chloroquine; Chronic Disease; Hepatitis; Humans; Immobilization; Immunosuppression Therapy; Immunosuppressive Agents; Liver Function Tests; Medication Errors; Mercaptopurine; Recurrence; Rest	1974
[Therapy of chronic hepatitis]. Minerva medica, 1974, Nov-17, Volume: 65, Issue:82 Topics: Anti-Inflammatory Agents; Antimetabolites; Azathioprine; Cholagogues and Choleretics; Chronic Disease; Cortisone; Diuretics; Glucocorticoids; Hepatitis; Humans; Immunosuppressive Agents; Liver Function Tests; Mercaptopurine; Methylprednisolone; Prednisone	1974
[Treatment of chronic hepatitis]. Les Cahiers de medecine, 1974, Oct-15, Volume: 15, Issue:10 Topics: Chronic Disease; Cortisone; Diet Therapy; Glucocorticoids; Hepatitis; Humans; Immunosuppressive Agents; Mercaptopurine	1974
[Treatment of chronic hepatitis]. Zeitschrift fur arztliche Fortbildung, 1974, Volume: 68, Issue:5 Topics: Azathioprine; Chronic Disease; Diet Therapy; Dietary Carbohydrates; Dietary Proteins; Female; Hepatitis; Hot Temperature; Humans; Liver; Liver Cirrhosis; Mercaptopurine; Middle Aged; Penicillamine; Prednisone; Pregnancy; Pregnancy Complications; Rest; Splenectomy	1974
Immunosuppressive therapy. The American journal of the medical sciences, 1973, Volume: 265, Issue:2 Topics: Anemia, Hemolytic, Autoimmune; Antigen-Antibody Reactions; Arthritis, Rheumatoid; Azathioprine; Crohn Disease; Cyclophosphamide; Female; Glomerulonephritis; Glucocorticoids; Hepatitis; Humans; Immunity; Immunity, Cellular; Immunosuppression Therapy; Immunosuppressive Agents; Male; Mercaptopurine; Methotrexate; Nephrotic Syndrome; Purpura, Thrombocytopenic	1973
[Immunosuppressive therapy of chronic aggressive hepatitis]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Oct-15, Volume: 28, Issue:20 Topics: Adult; Azathioprine; Chronic Disease; Female; Glucocorticoids; Hepatitis; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Male; Mercaptopurine; Middle Aged; Time Factors	1973
[Blast transformation of lymphocytes in chronic liver diseases]. Biulleten' eksperimental'noi biologii i meditsiny, 1972, Volume: 73, Issue:8 Topics: Adolescent; Adult; DNA; Hepatitis; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Extracts; Lymphocyte Activation; Mercaptopurine; Middle Aged; Prednisolone	1972
[Various results of immunologic studies on chronic liver diseases]. Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1972, Volume: 32, Issue:1 Topics: Chronic Disease; Hepatitis; Hepatitis B Antigens; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Liver Cirrhosis; Liver Diseases; Lymphocyte Activation; Mercaptopurine; Prednisolone	1972
[Experience with immunosuppressive therapy in chronic aggressive hepatitis]. Vutreshni bolesti, 1972, Volume: 11, Issue:3 Topics: Autoimmune Diseases; Azathioprine; Hepatitis; Humans; Immunosuppressive Agents; Mercaptopurine; Prednisone; Tolbutamide	1972
Management of chronic active hepatitis. Rocky Mountain medical journal, 1972, Volume: 69, Issue:2 Topics: Azathioprine; Chronic Disease; Diet Therapy; Hepatitis; Humans; Mercaptopurine; Prednisolone; Rest	1972
[Treatment of chronic active hepatitis by 6-mercaptopurine and immuran (azathioprine)]. Sovetskaia meditsina, 1972, Volume: 35, Issue:2 Topics: Adolescent; Adult; Aged; Azathioprine; Chronic Disease; Female; Hepatitis; Humans; Liver Cirrhosis; Male; Mercaptopurine; Middle Aged	1972
[Outlines for the use of immunosuppressive therapy in chronic aggressive hepatitis]. Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:6 Topics: Azathioprine; Chronic Disease; Cortisone; Hepatitis; Hepatitis B virus; Immunoglobulin A; Immunoglobulin G; Immunoglobulins; Immunosuppression Therapy; Mercaptopurine; Prednisone; Recurrence	1972
[Effect of therapy using combination of immunosuppressive agents in active chronic hepatitis--report of 2 cases and a review of the literature]. Nihon rinsho. Japanese journal of clinical medicine, 1972, Volume: 30, Issue:3 Topics: Adult; Azathioprine; Chronic Disease; Hepatitis; Humans; Male; Mercaptopurine; Prednisolone	1972
[Long term and permanent therapy of chronic hepatitis]. Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:8 Topics: Autoimmune Diseases; Chronic Disease; Cortisone; Cyclophosphamide; Female; Hepatitis; Hepatitis A; Humans; Liver Cirrhosis; Long-Term Care; Lupus Erythematosus, Systemic; Mercaptopurine; Penicillamine; Tuberculosis, Hepatic	1970
[Therapy of chronic active hepatitis with 6-mercaptopurine]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1970, Jan-01, Volume: 23, Issue:1 Topics: Adult; Chronic Disease; Hepatitis; Humans; Male; Mercaptopurine	1970
[Treatment and prognosis of chronic active hepatitis]. Nihon rinsho. Japanese journal of clinical medicine, 1970, Volume: 28, Issue:2 Topics: Adrenal Cortex Hormones; Adult; Chronic Disease; Female; Hepatitis; Humans; Liver Function Tests; Male; Mercaptopurine; Middle Aged; Prognosis	1970
Long-term results of therapy in patients with chronic liver disease associated with hypergammaglobulinemia. The American journal of medicine, 1969, Volume: 47, Issue:5 Topics: Adolescent; Biopsy; Blood Protein Disorders; Child; Chronic Disease; Cortisone; Female; gamma-Globulins; Hepatitis; Hepatomegaly; Humans; Liver; Liver Diseases; Liver Function Tests; Liver Regeneration; Male; Mercaptopurine; Microscopy, Electron; Prednisone; Prognosis; Serum Albumin; Splenomegaly	1969
[Experiences with 6-mercaptopurine therapy in active chronic hepatopathies]. Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1969, Volume: 22 Topics: Adolescent; Adult; Autoimmune Diseases; Chronic Disease; Female; Hepatitis; Humans; Liver Cirrhosis; Male; Mercaptopurine; Middle Aged; Prednisone	1969
[Therapeutic results in active chronic hepatopathies using 6-mercaptopurine]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1969, Jan-01, Volume: 24, Issue:1 Topics: Adolescent; Adult; Female; Hepatitis; Humans; Leukopenia; Liver Cirrhosis; Male; Mercaptopurine; Middle Aged; Prednisolone; Thrombocytopenia	1969
[Immunosuppression with 6-mercaptopurine in chronic hepatitis]. Die Medizinische Welt, 1969, Feb-22, Volume: 8 Topics: Alanine Transaminase; Arthritis, Rheumatoid; Aspartate Aminotransferases; Chronic Disease; Hepatitis; Humans; Liver Function Tests; Male; Mercaptopurine; Middle Aged	1969
Circulating anticoagulant (antifactor 8 treated with immunosuppressive drugs. Thrombosis et diathesis haemorrhagica, 1969, Apr-30, Volume: 21, Issue:2 Topics: Adult; Anticoagulants; Azathioprine; Blood Cell Count; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Platelets; Factor VIII; Female; Hematocrit; Hematoma; Hepatitis; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Middle Aged; Nitrofurazone; Prednisone; Pregnancy; Pregnancy Complications; Transfusion Reaction	1969
[Results of therapy of active chronic hepatopathies with 6-mercaptopurine]. Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1969, Apr-15, Volume: 24, Issue:8 Topics: Adolescent; Adult; Antimetabolites; Azaguanine; Azathioprine; Chronic Disease; Cyclophosphamide; Female; Hepatitis; Humans; Liver Cirrhosis; Male; Mercaptopurine; Middle Aged; Prednisone; Thioguanine	1969
[Early diagnosis and treatment of post-transfusion hepatitis (serum hepatitis) and chronic hepatitis]. Naika. Internal medicine, 1969, Volume: 23, Issue:6 Topics: Acute Disease; Adult; Alanine Transaminase; Chronic Disease; Hepatitis; Hepatitis B; Humans; Liver Function Tests; Male; Mercaptopurine; Middle Aged	1969
[Lupus inflammation of the liver (Lupoid hepatitis)]. Polskie Archiwum Medycyny Wewnetrznej, 1968, Volume: 41, Issue:5 Topics: Adult; Autoimmune Diseases; Female; Hepatitis; Humans; Lupus Erythematosus, Systemic; Mercaptopurine; Neutrophils; Serologic Tests	1968
[Studies on renin-angiotensin system. I. Angiotensinase activities in hepatic disorders]. Japanese circulation journal, 1968, Volume: 32, Issue:3 Topics: Adult; Angiotensin II; Animals; Bile Duct Neoplasms; Biliary Tract Diseases; Blood Pressure; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloramphenicol; Endopeptidases; Erythromycin; Female; Gout; Hepatitis; Humans; Hypertension; Liver; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Liver Neoplasms; Male; Mercaptopurine; Middle Aged; Nephrotic Syndrome; Rats	1968
Natural history of active chronic hepatitis. II. Pathology, pathogenesis and clinico-pathological correlation. Australasian annals of medicine, 1968, Volume: 17, Issue:4 Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Biliary Tract Diseases; Biopsy; Child; Child, Preschool; Cholestasis; Chronic Disease; Diagnosis, Differential; Female; Hepatitis; Hepatitis A; Humans; Infant; Infant, Newborn; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male; Mercaptopurine; Middle Aged; Necrosis	1968
[Contribution on the therapy of chronic liver parenchymal damage with 6-mercaptopurine]. Medizinische Klinik, 1968, Sep-06, Volume: 63, Issue:36 Topics: Adult; Alanine Transaminase; Bilirubin; Blood Glucose; Chronic Disease; Female; Hepatitis; Humans; Liver Cirrhosis; Male; Mercaptopurine; Middle Aged; Prednisolone	1968
The treatment of active chronic hepatitis with 6-mercaptopurine and azathioprine. Australasian annals of medicine, 1967, Volume: 16, Issue:4 Topics: Acute Disease; Adolescent; Adult; Azathioprine; Child; Chronic Disease; Female; Follow-Up Studies; Hepatitis; Humans; Liver; Liver Function Tests; Male; Mercaptopurine; Middle Aged; Prednisone; Prognosis	1967
Mercaptopurine hepatotoxicity in a patient with chronic active hepatitis. Archives of internal medicine, 1967, Volume: 120, Issue:6 Topics: Acute Kidney Injury; Adolescent; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Creatinine; Female; gamma-Globulins; Hepatitis; Humans; Hyperbilirubinemia; Kidney; Liver; Mercaptopurine; Serum Albumin; Serum Globulins	1967
[6-Mercaptopurine in the treatment of diffuse inflammatory liver diseases]. Revista clinica espanola, 1967, Dec-15, Volume: 107, Issue:5 Topics: Adult; Aged; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Function Tests; Male; Mercaptopurine; Middle Aged	1967
[Therapeutic effects of 6-mercaptopurine on liver diseases]. Nihon rinsho. Japanese journal of clinical medicine, 1966, Volume: 24, Issue:6 Topics: Adult; Female; Hepatitis; Humans; Liver Cirrhosis; Male; Mercaptopurine; Middle Aged	1966
[Round table conference. Therapy of hepatitis]. Nihon rinsho. Japanese journal of clinical medicine, 1966, Volume: 24, Issue:9 Topics: Diet Therapy; Hepatitis; Humans; Mercaptopurine	1966
Chronic active hepatitis treated with 6-mercaptopurine--sustained remission. Annals of internal medicine, 1966, Volume: 65, Issue:6 Topics: Adrenal Cortex Hormones; Adult; Female; Hepatitis; Humans; Mercaptopurine	1966
Experience with the use of 6-mercaptopurine and "Imuran" in the treatment of progressive hepatitis (active chronic hepatitis). Australasian annals of medicine, 1966, Volume: 15, Issue:3 Topics: Adolescent; Adult; Azathioprine; Female; Hepatitis; Humans; Mercaptopurine	1966
Experience with the use of 6-mercaptopurine and "Imuran" in the treatment of progressive hepatitis (active chronic hepatitis). Australasian annals of medicine, 1966, Volume: 15, Issue:3 Topics: Adolescent; Adult; Azathioprine; Female; Hepatitis; Humans; Mercaptopurine	1966
Autoimmune hepatitis. Annals of the New York Academy of Sciences, 1965, Jun-30, Volume: 124, Issue:2 Topics: Autoimmune Diseases; Diagnosis, Differential; Enzymes; Hepatitis; Humans; In Vitro Techniques; Liver Cirrhosis; Lupus Erythematosus, Systemic; Mercaptopurine; Transaminases	1965
[Treatment of chronic hepatitis and liver cirrhosis with 6-mercaptopurine and a methylhydrazine derivative]. Medizinische Klinik, 1965, Aug-20, Volume: 60, Issue:34 Topics: Adult; Aged; Female; Hepatitis; Humans; Hydrazines; Liver Cirrhosis; Liver Function Tests; Male; Mercaptopurine; Middle Aged	1965
[1st experience in the treatment of chronic hepatitis with 6-mercaptopurine and a methylhydrazine derivative]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1965, Volume: 71 Topics: Biopsy; Blood Chemical Analysis; Chronic Disease; Hepatitis; Humans; Hydrazines; Injections, Intravenous; Mercaptopurine	1965
TREATMENT OF ACTIVE CHRONIC HEPATITIS AND LUPOID HEPATITIS WITH 6-MERCAPTOPURINE AND AZOTHIOPRINE. Lancet (London, England), 1964, Apr-25, Volume: 1, Issue:7339 Topics: Adolescent; Anemia; Anemia, Pernicious; Antineoplastic Agents; Autoimmune Diseases; Azathioprine; Clinical Enzyme Tests; Drug Therapy; gamma-Globulins; Gastritis; Glossitis; Hepatitis; Hepatitis, Chronic; Humans; Liver Function Tests; Lupus Erythematosus, Systemic; Mercaptopurine; Prednisolone; Promazine; Thyroiditis; Toxicology; Transaminases; Transplantation Immunology	1964
SUPPRESSION OF PLASMA CELL HEPATITIS WITH 6-MERCAPTOPURINE. The American journal of medicine, 1964, Volume: 36 Topics: Adolescent; Antibody Formation; Arthritis; Arthritis, Juvenile; Blood Protein Disorders; Child; Cortisone; Hepatitis; Humans; Infectious Mononucleosis; Jaundice; Liver Function Tests; Mercaptopurine; Pathology; Plasma Cells; Splenomegaly; Toxicology	1964
HEPATOTOXICITY OF MERCAPTOPURINE. JAMA, 1964, Jun-01, Volume: 188 Topics: Blood Transfusion; Chemical and Drug Induced Liver Injury; Child; Hepatitis; Hepatitis B virus; Leukemia; Mercaptopurine; Pathology; Prednisone; Statistics as Topic; Toxicology	1964
CHRONIC PERSISTING HEPATITIS. The American journal of digestive diseases, 1964, Volume: 9 Topics: Cortisone; Diet; Diet Therapy; Drug Therapy; Hepatitis; Hepatitis A; Hepatitis, Chronic; Humans; Liver Cirrhosis; Mercaptopurine; Pathology; Prognosis; Rest	1964
[TREATMENT OF CHRONIC HEPATITIS WITH 6-MERCAPTOPURINE]. Svenska lakartidningen, 1964, Dec-02, Volume: 61 Topics: Drug Therapy; Hepatitis; Hepatitis A; Hepatitis, Chronic; Humans; Mercaptopurine; Viral Vaccines	1964
CURRENT STUDIES ON THE EFFECT ANTIMETABOLITES IN NEPHROSIS, OTHER NON-NEOPLASTIC DISEASES, AND EXPERIMENTAL ANIMALS. COMBINED CLINICAL STAFF CONFERENCE AT THE NATIONAL INSTITUTES OF HEALTH. Annals of internal medicine, 1963, Volume: 59 Topics: Agammaglobulinemia; Alanine Transaminase; Animals; Antimetabolites; Autoimmune Diseases; Clinical Enzyme Tests; Encephalomyelitis; Hepatitis; Hypersensitivity; Lupus Erythematosus, Systemic; Mercaptopurine; National Institutes of Health (U.S.); Nephrosis; Nephrotic Syndrome; Prednisone; Skin Tests; United States	1963
[ACTION OF NUCLEOSIDES AND ADENINE NUCLEOTIDES ON THE BIOSYNTHESIS OF PORPHYRINS]. Bulletin de la Societe de chimie biologique, 1963, Volume: 45 Topics: Adenine Nucleotides; Animals; Antimetabolites; Chemical and Drug Induced Liver Injury; Chick Embryo; Culture Media; Glycine; Hepatitis; Hexachlorocyclohexane; Hypnotics and Sedatives; Lead Poisoning; Levulinic Acids; Liver; Mercaptopurine; Metabolism; Nucleosides; Pharmacology; Porphyrias; Porphyrins; Pyridines; Rabbits; Rats; Research; Rhodopseudomonas; Succinates; Toxicology	1963
Hepatitis in association with prolonged 6-mercaptopurine therapy. Blood, 1959, Volume: 14, Issue:1 Topics: Hepatitis; Humans; Leukemia; Mercaptopurine; Viral Vaccines	1959