mercaptopurine has been researched along with Escherichia-coli-Infections* in 7 studies
7 other study(ies) available for mercaptopurine and Escherichia-coli-Infections
Article | Year |
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Immunological enhancement in the pathogenesis of pyelonephritis.
The role of the immune response in pyelonephritis was investigated by manipulation of the host's immune capacity using the immunosuppressive drugs 6-mercaptopurine, cyclophosphamide and thiamphenicol. Treatment with 6-mercaptopurine depressed the humoral immune response but did not have an adverse effect on the course of renal infection. Thiamphenicol administration prevented the development of pathological lesions but this was due to the anti-bacterial activity of thiamphenicol and not to its immunosuppressive activity. Pyelonephritic animals treated with cyclophosphamide did not produce anti-bacterial antibody. Despite this, cyclophosphamide-treated animals were able to eliminate organisms more readily from the infected kidney than untreated animals with a normal humoral immune response. We believe that blocking of the phenomenon of immunological enhancement explains these unexpected results and that the immune response to renal infection may have an immunoenhancing role protecting the bacterial cell from otherwise effective host defence mechanisms. Topics: Animals; Antibodies, Bacterial; Antibody Formation; Cyclophosphamide; Escherichia coli Infections; Female; Kidney; Mercaptopurine; Pyelonephritis; Rats; Thiamphenicol | 1976 |
Application of lysozyme and immunization with Escherichia coli 086 antigen in mice treated with 6-mercaptopurine.
Topics: Animals; Antigens, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Immunosuppressive Agents; Male; Mercaptopurine; Mice; Muramidase | 1974 |
[The experimental studies of anticorporeal administration of azathioprine].
Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Azathioprine; Escherichia coli Infections; Hemagglutination Tests; Immunosuppression Therapy; Mercaptopurine; Pyelonephritis; Rabbits | 1971 |
EFFECT OF 6-MERCAPTOPURINE ON ENDOTOXIN TOLERANCE.
Topics: Chromatography; Chromatography, Gel; Drug Tolerance; Endotoxins; Escherichia coli Infections; Fever; Immunoelectrophoresis; Immunosuppressive Agents; Mercaptopurine; Rabbits; Research; Toxicology; Ultracentrifugation | 1965 |
Acute appendicitis in childhood leukemia.
Topics: Adolescent; Appendicitis; Child; Child, Preschool; Escherichia coli Infections; Female; Humans; Leukemia; Male; Mercaptopurine; Mortality; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis | 1965 |
[APPLICATION OF METHOCLOPRAMIDE IN THE VOMITING OF INFANTS AND CHILDREN].
Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Anti-Bacterial Agents; Antiemetics; Calcium Chloride; Child; Drug Therapy; Escherichia coli Infections; Gastroenteritis; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Mercaptopurine; Toxicology; Vomiting | 1964 |
MYOCARDIAL ABSCESSES.
Topics: Abscess; Anti-Bacterial Agents; Aspergillosis; Candidiasis; Clostridium; Electrocardiography; Escherichia coli Infections; Geriatrics; Heart Diseases; Humans; Klebsiella; Mechlorethamine; Mercaptopurine; Pathology; Proteus; Staphylococcal Infections; Statistics as Topic; Steroids; Streptococcal Infections; Surgical Procedures, Operative | 1963 |