mercaptopurine has been researched along with Eosinophilic-Granuloma* in 3 studies
3 other study(ies) available for mercaptopurine and Eosinophilic-Granuloma
Article | Year |
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Recurrent Langerhans cell histiocytosis of the mandible.
We report a case of Langerhans cell histiocytosis with a restricted presentation (eosinophilic granuloma of the mandible) complicated by multiple reactivations. Topics: Antimetabolites; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Biopsy; Child; Cladribine; Curettage; Eosinophilic Granuloma; Female; Glucocorticoids; Histiocytosis, Langerhans-Cell; Humans; Mandibular Diseases; Mercaptopurine; Methotrexate; Prednisolone; Recurrence; Tomography, X-Ray Computed; Vinblastine | 2013 |
Treatment of recurrent eosinophilic granuloma with systemic therapy.
To describe the systemic treatment of recurrent eosinophilic granuloma.. Case report and review of Langerhans cell histiocytosis.. A 9-year-old boy had painful, right upper eyelid swelling. A computed tomography scan showed a right superolateral orbital mass with evidence of bony erosion. Frozen section evaluation was consistent with eosinophilic granuloma. Biopsy and curettage were performed. Systemic work-up was negative for extraorbital disease. Recurrence of the orbital mass 6 weeks after surgery was confirmed by magnetic resonance imaging (MRI). Four weeks after treatment with prednisone and vinblastine, MRI showed a marked decrease in the size of the orbital lesion. Additional treatment with 6-mercaptopurine and methotrexate was initiated, and MRI 6 months later showed complete resolution of the lesion.. The treatment of recurrent eosinophilic granuloma is challenging. The goal is to effectively cure the lesion with minimal short-term and long-term side effects. Systemic steroids, vinca alkaloids, antimetabolites, and antifols are preferred because they have less toxicity and mutagenicity. Combination chemotherapy used in conjunction with treatment by a pediatric hematologist/oncologist appears to be an effective method of treating recurrent disease. Topics: Antineoplastic Combined Chemotherapy Protocols; Child; Drug Therapy, Combination; Eosinophilic Granuloma; Glucocorticoids; Humans; Magnetic Resonance Imaging; Male; Mercaptopurine; Orbital Diseases; Prednisone; Recurrence; Vinblastine; X-Rays | 2003 |
MALIGNANT LYMPHOMA PRESENTING AS NECROTIZING EOSINOPHILIC GRANULOMATOSIS.
Topics: Bone Marrow Examination; Drug Therapy; Eosinophilic Granuloma; Lymphoma; Mechlorethamine; Mercaptopurine; Neoplasms; Pathology; Prednisone | 1965 |