mercaptopurine has been researched along with Anemia--Hemolytic--Autoimmune* in 37 studies
2 review(s) available for mercaptopurine and Anemia--Hemolytic--Autoimmune
Article | Year |
---|---|
Immunosuppressive therapy in the treatment of autoimmune diseases.
Topics: Adolescent; Adrenal Cortex Hormones; Alkylating Agents; Anemia; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Antilymphocyte Serum; Arthritis, Rheumatoid; Autoimmune Diseases; Azathioprine; Colchicine; Cyclosporins; Danazol; Female; Hepatitis, Chronic; Humans; Immunoglobulin G; Immunosuppressive Agents; Levamisole; Lupus Erythematosus, Systemic; Male; Mercaptopurine; Methotrexate; Multiple Sclerosis; Pregnancy | 1984 |
Immunosuppressive therapy. 1.
Topics: Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Antimetabolites; Arthritis, Rheumatoid; Azathioprine; Blood Coagulation Disorders; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Cyclophosphamide; Dermatomyositis; Factor VIII; Hepatitis; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Prednisolone; Purpura, Thrombocytopenic; Scleroderma, Systemic | 1972 |
2 trial(s) available for mercaptopurine and Anemia--Hemolytic--Autoimmune
Article | Year |
---|---|
Immunosuppressive therapy. 1.
Topics: Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Antimetabolites; Arthritis, Rheumatoid; Azathioprine; Blood Coagulation Disorders; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Cyclophosphamide; Dermatomyositis; Factor VIII; Hepatitis; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Prednisolone; Purpura, Thrombocytopenic; Scleroderma, Systemic | 1972 |
[Immuno-suppressive treatment in 15 patients with autoimmune affections or diseases of immunological pathogenesis].
Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Clinical Trials as Topic; Humans; Lupus Erythematosus, Systemic; Mercaptopurine; Polyarteritis Nodosa; Purpura | 1966 |
34 other study(ies) available for mercaptopurine and Anemia--Hemolytic--Autoimmune
Article | Year |
---|---|
Immune hemolytic anemia induced by 6-mercaptopurine.
Myelosuppression is the main hematotoxic effect of 6-mercaptopurine (6-MP), which is an antimetabolite chemotherapy drug. Immune hemolytic anemia associated with this drug has not been previously reported.. A 67-year-old man with chronic myelomonocytic leukemia presented with anemia 2 weeks after 6-MP therapy had been initiated. Additional tests provided laboratory evidence of hemolysis. When treatment was stopped, the patient's condition and laboratory results showed a progressive improvement.. The direct antiglobulin test was positive for IgG. The eluate and the serum were not reactive with panel red cells but reacted with 6-MP-treated red cells, while the normal serum pool was unreactive. The direct antiglobulin test was no longer positive by 20 days after the cessation of 6-MP therapy.. This drug, 6-MP, should be added to the list of drugs that have been reported to cause immune hemolytic anemia by means of the so-called hapten mechanism. Topics: Aged; Anemia, Hemolytic, Autoimmune; Coombs Test; Humans; Leukemia, Myelomonocytic, Chronic; Male; Mercaptopurine | 2000 |
A case of Evans syndrome, successfully treated with 6-mercaptopurine.
Topics: Anemia, Hemolytic, Autoimmune; Child; Humans; Male; Mercaptopurine; Purpura, Thrombocytopenic; Syndrome | 1986 |
Superior sagittal sinus thrombosis associated with Evans' syndrome of haemolytic anaemia.
A case of superior sagittal sinus thrombosis associated with Evans' syndrome of immune haemolytic anaemia is reported. The neurological symptoms and signs were headaches, right quadrant hemianopia, dyslexia without agraphia, motor aphasia, numbness in and weakness of the right upper extremity, papilloedema and coma. The cerebral venous sinus thrombosis, involving cerebral veins, superior sagittal sinus and straight sinus, was diagnosed by cerebral angiography. It is noteworthy that the superior sagittal sinus thrombosis occurred during a haematological recovery period, with rapid responses to treatment with 6-mercaptopurine and high doses of adrenocorticosteroids. Following a reduction in the doses of these drugs, the symptoms and signs related to the superior sagittal sinus thrombosis gradually subsided, and the haematological pictures remained in remission. Topics: Adult; Anemia, Hemolytic, Autoimmune; Cranial Sinuses; Dexamethasone; Humans; Intracranial Embolism and Thrombosis; Male; Mercaptopurine; Syndrome; Thrombophlebitis | 1985 |
[Autoimmune hemolytic anaemia in childhood. Review and report of one case (author's transl)].
Autoimmune hemolytic anaemia (AIHA) in childhood is associated with antibodies produced by the patient himself, which coat his red cells causing their hemolysis. Although in some cases no underlying disease could be found, in the majority of children a virus etiology is apparent. There are very few reports regarding the use of treatment with immunsuppressive agents and the possible benefit. The article reports one case of AIHA. The patient developed at age 6 months a prolonged chronic form of AIHA complicated by thrombopenic purpura. The recent knowledge about pathogenesis, clinical phenomena, serology and prognosis is discussed. Treatment with corticosteroids, azathioprine or cyclophosphamide failed to benefit. Splenectomy and 6-mercaptopurin therapy (3 months) resulted in a complete remission. Topics: Anemia, Hemolytic, Autoimmune; Autoantibodies; Azathioprine; Chronic Disease; Cortisone; Cyclophosphamide; Humans; Infant; Male; Mercaptopurine; Splenectomy; Virus Diseases | 1977 |
Drug therapy of autoimmune hemolytic anemia.
Topics: Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Cyclophosphamide; Drug Administration Schedule; Hemoglobinuria, Paroxysmal; Heparin; Humans; Mercaptopurine; Prognosis; Splenectomy; Thymectomy | 1976 |
Disseminated toxoplasmosis in the compromised host. A report of five cases.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Autopsy; Azathioprine; Brain; Breast Neoplasms; Female; Hodgkin Disease; Humans; Immunosuppression Therapy; Infection Control; Infections; Kidney Transplantation; Lung; Lupus Erythematosus, Systemic; Male; Mercaptopurine; Middle Aged; Myocardium; Neoplasm Metastasis; Prednisone; Toxoplasmosis; Transplantation, Homologous | 1974 |
[Purine analogues in autoimmune diseases--results of studies lasting several years].
Topics: Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Azathioprine; Humans; Lupus Erythematosus, Systemic; Mercaptopurine; Time Factors | 1973 |
[The evolution of idiopathic autoimmune hemolytic anemia].
Topics: Age Factors; Anemia, Hemolytic, Autoimmune; Antibodies; Chlorambucil; Cyclophosphamide; Female; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Prednisone; Pregnancy; Pregnancy Complications, Hematologic; Sex Factors; Splenectomy | 1973 |
Immunosuppressive therapy.
Topics: Anemia, Hemolytic, Autoimmune; Antigen-Antibody Reactions; Arthritis, Rheumatoid; Azathioprine; Crohn Disease; Cyclophosphamide; Female; Glomerulonephritis; Glucocorticoids; Hepatitis; Humans; Immunity; Immunity, Cellular; Immunosuppression Therapy; Immunosuppressive Agents; Male; Mercaptopurine; Methotrexate; Nephrotic Syndrome; Purpura, Thrombocytopenic | 1973 |
[Problems in Evan's syndrome. Clinical and nuclear medicine studies].
Topics: Adult; Anemia, Hemolytic, Autoimmune; Chromium Isotopes; Coombs Test; Cortisone; Female; Humans; Leukopenia; Male; Mercaptopurine; Middle Aged; Purpura, Thrombocytopenic; Splenectomy; Syndrome | 1973 |
[Immunosuppressive long-term therapy of autoimmune diseases in hematology].
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Antimetabolites; Arthritis, Rheumatoid; Autoimmune Diseases; Azathioprine; Female; Humans; Immunosuppressive Agents; Long-Term Care; Lupus Erythematosus, Systemic; Male; Mercaptopurine; Middle Aged; Purpura, Thrombocytopenic | 1972 |
[Immunosuppressive therapy in immuno-hematologic diseases].
Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Humans; Immunosuppressive Agents; Mercaptopurine; Thrombocytopenia | 1972 |
[Immunosuppressive therapy].
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Antibody Formation; Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Immunosuppressive Agents; Liver; Liver Function Tests; Lupus Erythematosus, Systemic; Lymphocyte Activation; Mercaptopurine; Middle Aged; Time Factors | 1971 |
[A case of severe autoimmune hemolytic anemia of unknown etiology in a 50-day-old infant, cured with 6-mercaptopurine].
Topics: Anemia, Hemolytic, Autoimmune; Blood Transfusion; Erythrocytes; Erythropoiesis; Female; Humans; Infant; Mercaptopurine; Prednisone; Soaps | 1971 |
Testing for Ph 1 chromosome on mailed specimens of peripheral blood.
Topics: Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; Antimetabolites; Blood Specimen Collection; Bone Marrow Diseases; Busulfan; Chromosome Aberrations; Diuretics; Hodgkin Disease; Humans; Karyotyping; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemoid Reaction; Mercaptopurine; Prednisone; Specimen Handling; Thrombocytopenia; Time Factors | 1971 |
[Therapy of anemias].
Topics: Anemia; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Anemia, Sideroblastic; Azathioprine; Dactinomycin; Fluorouracil; Humans; Immunosuppressive Agents; Mercaptopurine | 1970 |
[Immunosuppressive agents in hematology].
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Agranulocytosis; Anemia, Hemolytic, Autoimmune; Azathioprine; Child; Child, Preschool; Female; Hematologic Diseases; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Male; Mercaptopurine; Middle Aged; Prednisone; Purpura, Thrombocytopenic; Splenectomy; Thrombocytopenia | 1970 |
[Immunosuppressive agents in hematology].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Agranulocytosis; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Azathioprine; Child; Child, Preschool; Female; Humans; Immunosuppressive Agents; Infant; Male; Mercaptopurine; Middle Aged; Prednisone; Purpura, Thrombocytopenic; Splenectomy; Thrombocytopenia | 1970 |
[Immunosuppressive therapy].
Topics: Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Animals; Autoimmune Diseases; Azathioprine; Corneal Transplantation; Dactinomycin; Humans; Immunosuppressive Agents; Kidney Diseases; Mercaptopurine; Plasmacytoma; Psoriasis; Transplantation Immunology | 1970 |
[Treatment of acquired hemolytic anemia with immunosuppressive drugs].
Topics: Adrenal Cortex Hormones; Adult; Aged; Anemia, Hemolytic, Autoimmune; Child; Humans; Male; Mercaptopurine; Middle Aged | 1970 |
[Experience in the therapy of autoimmune diseases].
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Dactinomycin; Female; Granuloma, Lethal Midline; Humans; Male; Mercaptopurine; Middle Aged; Prednisone; Purpura, Thrombocytopenic; Thrombocytopenia | 1969 |
Lymphocyte transformation tests in patients under treatment with immunosuppressive drugs.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Arthritis, Rheumatoid; Azathioprine; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Lectins; Lupus Erythematosus, Systemic; Lymphocyte Activation; Lymphocytes; Male; Mercaptopurine; Middle Aged; Purpura, Thrombocytopenic; Streptolysins | 1969 |
[Immunosuppressive therapy of autoimmune hemolytic anemias. (Preliminary report)].
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Cushing Syndrome; Female; Humans; Immunosuppressive Agents; Male; Mercaptopurine; Middle Aged; Prednisone | 1969 |
Autoimmune hemolytic anemia with hemoglobinemia and hemoglobinuria in the absence of a demonstrable hemolysin or complement-binding antibody.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Antibodies; Cellulose; Chromatography; Complement System Proteins; Female; Heart Failure; Hemagglutination Tests; Hematocrit; Hemoglobinuria; Hemolysin Proteins; Humans; Mercaptopurine; Methicillin; Myocardial Infarction; Pneumonia; Prednisolone | 1969 |
6-mercaptopurine administration to NZB mice.
Topics: Anemia, Hemolytic, Autoimmune; Animals; Antibody Formation; Coombs Test; Hematocrit; Male; Mercaptopurine; Methods; Mice | 1968 |
Azathioprine in myeloproliferative and autoimmune disorders.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Azathioprine; Colitis, Ulcerative; Female; Humans; Lectins; Leukemia; Male; Mercaptopurine; Middle Aged; Nephrotic Syndrome; Purpura, Thrombotic Thrombocytopenic | 1968 |
[The immunosuppressive agents. 3. The immunosuppressive agents in hematology].
Topics: Anemia, Hemolytic, Autoimmune; Autoimmune Diseases; Azathioprine; Cyclophosphamide; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Purpura, Thrombocytopenic; Thioguanine | 1967 |
Thrombocytopenic purpura in patient with autoimmune haemolytic anaemia, successfully treated with mercaptopurine.
Topics: Adolescent; Adrenocorticotropic Hormone; Anemia, Hemolytic, Autoimmune; Humans; Male; Mercaptopurine; Prednisone; Purpura, Thrombotic Thrombocytopenic; Splenectomy | 1967 |
[Therapeutic results in 45 cases of apparently extra-globular, acquired hemolytic anemia].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anemia, Hemolytic, Autoimmune; Blood Transfusion; Humans; Mercaptopurine; Purpura, Thrombocytopenic; Splenectomy; Thioguanine | 1966 |
Treatment of collagen diseases with cytostatics.
Topics: Adrenal Cortex Hormones; Adult; Aged; Anemia, Hemolytic, Autoimmune; Arthritis, Rheumatoid; Asthma; Azathioprine; Collagen Diseases; Female; Humans; Leukopenia; Lupus Erythematosus, Systemic; Male; Mercaptopurine; Middle Aged; Polyarteritis Nodosa; Polymyalgia Rheumatica; Thyroiditis | 1965 |
Autoimmune hemolytic anemia in an infant. Report of a case treated unsuccessfully with thymectomy.
Topics: Anemia, Hemolytic, Autoimmune; Antivenins; Black or African American; Female; Heparin; Humans; Infant, Newborn; Mercaptopurine; Splenectomy; Thymectomy | 1965 |
[TREATMENT WITH 6-MERCAPTOPURINE IN AUTOIMMUNE HEMOLYTIC ANEMIA].
Topics: Anemia; Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Humans; Mercaptopurine | 1964 |
CHRONIC LEUKEMIA.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Alkylating Agents; Anemia; Anemia, Hemolytic, Autoimmune; Busulfan; Chlorambucil; Cyclophosphamide; Folic Acid Antagonists; Hemorrhage; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Neoplasms; Nitrogen Mustard Compounds; Phosphorus Isotopes; Splenectomy; Thioguanine; Triethylenemelamine | 1964 |
The treatment of autoimmune hemolytic anemia with 6-mercaptopurine and thioguanine.
Topics: Anemia, Hemolytic, Autoimmune; Humans; Mercaptopurine; Thioguanine | 1962 |