mercaptopurine and Afibrinogenemia

mercaptopurine has been researched along with Afibrinogenemia* in 4 studies

Reviews

1 review(s) available for mercaptopurine and Afibrinogenemia

Article	Year
[Transient hypofibrinogenemia induced by prednisolone in a case of acute lymphoblastic leukemia]. [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:7 We report here a patient with acute lymphoblastic leukemia (ALL) in whom hypofibrinogenemia developed during chemotherapy. The patient was a 65-year-old female who was diagnosed as having common ALL, and she was treated with BHAC-DMPV (enocitabine: 160 mg, daunorubicin : 40 mg, 6-MP: 35 mg, prednisolone (PSL): 60 mg, and vincristine: 2 mg). Hypofibrinogenemia appeared promptly each chemotherapy, including PSL was given. To ascertain a correlation between hypofibrinogenemia and the drugs given in this patient, a trial administration of PSL was attempted during a complete remission state. The level of fibrinogen, in terms of the amount of antigen or coagulability, decreased during PSL treatment, although the levels of AT III, plasminogen, alpha 2PI.Plm complex, and FDP did not change. Thus, it is difficult to speculate that PSL induced destruction of leukemia cells and release of protease from the cells resulting in fibrinolysis and hypofibrinogenemia in this case. These findings also suggest that the administration of only PSL could induce hypofibrinogenemia. Topics: Afibrinogenemia; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine	1989

Article

Year

[Transient hypofibrinogenemia induced by prednisolone in a case of acute lymphoblastic leukemia].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:7

We report here a patient with acute lymphoblastic leukemia (ALL) in whom hypofibrinogenemia developed during chemotherapy. The patient was a 65-year-old female who was diagnosed as having common ALL, and she was treated with BHAC-DMPV (enocitabine: 160 mg, daunorubicin : 40 mg, 6-MP: 35 mg, prednisolone (PSL): 60 mg, and vincristine: 2 mg). Hypofibrinogenemia appeared promptly each chemotherapy, including PSL was given. To ascertain a correlation between hypofibrinogenemia and the drugs given in this patient, a trial administration of PSL was attempted during a complete remission state. The level of fibrinogen, in terms of the amount of antigen or coagulability, decreased during PSL treatment, although the levels of AT III, plasminogen, alpha 2PI.Plm complex, and FDP did not change. Thus, it is difficult to speculate that PSL induced destruction of leukemia cells and release of protease from the cells resulting in fibrinolysis and hypofibrinogenemia in this case. These findings also suggest that the administration of only PSL could induce hypofibrinogenemia.

Topics: Afibrinogenemia; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Mercaptopurine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisolone; Vincristine

1989

Other Studies

3 other study(ies) available for mercaptopurine and Afibrinogenemia

Article	Year
Intravascular coagulation-fibrinolysis (ICF) syndrome and malignancy: historical review and report of two cases with metastatic carcinoid and with acute myelomonocytic leukemia. Thrombosis et diathesis haemorrhagica. Supplementum, 1969, Volume: 36 Topics: Adult; Afibrinogenemia; Aged; Anticoagulants; Antifibrinolytic Agents; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Platelets; Blood Transfusion; Carcinoid Tumor; Female; Fibrinogen; Fibrinolysis; History, 19th Century; History, 20th Century; Humans; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Mitomycins; Prednisone; Steroids	1969
Treatment of AGL. Archives of internal medicine, 1969, Volume: 123, Issue:2 Topics: Adult; Afibrinogenemia; Aged; Anemia; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Humans; Hydroxyzine; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukopenia; Mercaptopurine; Methotrexate; Middle Aged; Polycythemia Vera; Prednisone; Primary Myelofibrosis; Splenomegaly; Vincristine	1969
ACUTE PROMYELOCYTIC LEUKEMIA WITH FIBRINOGEN AND FACTOR V DEFICIENCIES. Blood, 1964, Volume: 23 Topics: Afibrinogenemia; Blood Cell Count; Bone Marrow Examination; Drug Therapy; Factor V Deficiency; Fibrinogen; Humans; Hypoprothrombinemias; Leukemia; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Mercaptopurine; Pathology; Statistics as Topic; Thrombocytopenia	1964