mercaptoethanol has been researched along with Waldenstrom Macroglobulinemia in 38 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
Waldenstrom Macroglobulinemia: A lymphoproliferative disorder characterized by pleomorphic B-LYMPHOCYTES including PLASMA CELLS, with increased levels of monoclonal serum IMMUNOGLOBULIN M. There is lymphoplasmacytic cells infiltration into bone marrow and often other tissues, also known as lymphoplasmacytic lymphoma. Clinical features include ANEMIA; HEMORRHAGES; and hyperviscosity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with Waldenstr]om's macroglobulinemia whose serum demonstrated properties of both pyroglobulin and cryoglobulin was studied." | 1.31 | Immunochemical characterization of monoclonal protein in the serum of a patient with Waldenstr]om's macroglobulinemia showing both pyroglobulin and cryoglobulin properties. ( Ikeda, H; Kohgo, Y; Matsuno, K; Moriyama, T; Torimoto, Y, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (97.37) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (2.63) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KORNGOLD, L | 1 |
| VAN LEEUWEN, G | 1 |
| CUMMINGS, NA | 1 |
| FRANKLIN, EC | 2 |
| SZABOLCS, M | 1 |
| OROSZ, L | 1 |
| HANKISS, J | 1 |
| REISNER, CA | 1 |
| Moriyama, T | 1 |
| Torimoto, Y | 1 |
| Kohgo, Y | 1 |
| Ikeda, H | 1 |
| Matsuno, K | 1 |
| Hester, RB | 1 |
| Mole, JE | 1 |
| Schrohenloher, RE | 5 |
| Sørensen, S | 1 |
| Andersen, BR | 2 |
| McAninch, JR | 1 |
| Patterson, R | 1 |
| Hege, JS | 1 |
| Epstein, WV | 1 |
| Invernizzi, F | 1 |
| Cattaneo, R | 2 |
| Rosso di San Secondo, V | 1 |
| Balestrieri, G | 2 |
| Zanussi, C | 1 |
| Suzuki, T | 1 |
| Deutsch, HF | 1 |
| Ito, C | 1 |
| Hashimoto, I | 1 |
| Onuma, Y | 1 |
| Ishitoya, Y | 1 |
| Goodman, A | 1 |
| Inman, FP | 3 |
| Mestecky, J | 1 |
| Eskeland, T | 1 |
| Harboe, M | 2 |
| Haegert, DG | 1 |
| Hallberg, T | 1 |
| Coombs, RR | 1 |
| Solheim, BG | 1 |
| Wetter, O | 2 |
| Jahnke, K | 1 |
| Dominguez, CJ | 1 |
| Caggiano, V | 1 |
| Kochwa, S | 1 |
| Wasserman, LR | 1 |
| Beale, D | 1 |
| Feinstein, A | 1 |
| Mackenzie, MR | 1 |
| Warner, NL | 1 |
| Linscott, WD | 1 |
| Fudenberg, HH | 2 |
| Kasukawa, R | 2 |
| Yoshida, T | 2 |
| Milgrom, F | 2 |
| Castaldi, PA | 1 |
| Penny, R | 1 |
| Herberman, RB | 1 |
| Yoshida, H | 1 |
| Morris, JE | 1 |
| Bazzi, C | 1 |
| Simonati, V | 1 |
| Dammacco, F | 1 |
| Giustino, V | 1 |
| Bonomo, L | 1 |
| Hansson, UB | 1 |
| Laurell, CB | 1 |
| Leikola, J | 1 |
| Vyas, GN | 1 |
| Perkins, HA | 1 |
| Mukkur, TK | 1 |
| Bennett, JC | 1 |
| Crome, P | 1 |
| Moffatt, B | 1 |
| Tesar, JT | 1 |
| Schmid, FR | 1 |
| Haisty, WK | 1 |
| Hartz, WH | 1 |
| Egorov, AM | 1 |
| Chernyak, VY | 1 |
| Dunaevsky, YE | 1 |
| Gavrilova, EM | 1 |
| Moiseev, VL | 1 |
38 other studies available for mercaptoethanol and Waldenstrom Macroglobulinemia
| Article | Year |
|---|---|
Macroglobulinemia. III. The effect of mercaptoethanol on the antigenic structure of macroglobulins.
Topics: Antigens; Epitopes; Ethanol; gamma-Globulins; Immune Sera; Macroglobulins; Mercaptoethanol; Proteins | 1959 |
ATYPICAL GAMMA-1-A-GLOBULIN WITH THE ELECTROPHORETIC PROPERTIES OF AN ALPHA-2-GLOBULIN OCCURRING IN MULTIPLE MYELOMA.
Topics: Alpha-Globulins; Blood Protein Electrophoresis; Chromatography; Diagnosis, Differential; gamma-Globu | 1965 |
PHYSICO-CHEMICAL AND IMMUNOLOGICAL PROPERTIES OF PURIFIED PATHOLOGICAL MACROGLOBULIN.
Topics: Biochemical Phenomena; Biochemistry; Blood Protein Electrophoresis; Chemical Phenomena; Chemistry, P | 1965 |
Studies of mercaptoethanol-dissociated normal human 19 S gamma-globulin and pathologic macroglobulins from patients with macroglobulinemia.
Topics: gamma-Globulins; Macroglobulins; Mercaptoethanol; Serum Globulins; Waldenstrom Macroglobulinemia | 1961 |
Immunochemical characterization of monoclonal protein in the serum of a patient with Waldenstr]om's macroglobulinemia showing both pyroglobulin and cryoglobulin properties.
Topics: Aged; Amidohydrolases; Chemical Precipitation; Chromatography, High Pressure Liquid; Cold Temperatur | 2000 |
Evidence for the absence of noncovalent bonds in the Fcmu region of IgM.
Topics: Amino Acid Sequence; Carbohydrates; Chromatography, Gas; Chromatography, Gel; Electrophoresis, Disc; | 1975 |
Monoclonal IgM kappa with rheumatoid factor activity and cryoprecipitability identified only by immunofixation electrophoresis after 2-mercaptoethanol treatment.
Topics: Aged; Antibodies, Monoclonal; Cryoglobulins; Humans; Immunoelectrophoresis; Immunoglobulin kappa-Cha | 1988 |
The incidence of precipitating activity in monoclonal proteins.
Topics: Animals; Antigens; Ascaris; Chromatography; Dinitrophenols; gamma-Globulins; Humans; Immunodiffusion | 1971 |
Antibody islet forming-cells: localized hemolysis inhibition in gel.
Topics: Animals; Antibody-Producing Cells; Antigen-Antibody Reactions; Cattle; Chromatography, DEAE-Cellulos | 1972 |
Pyroglobulinemia. A report of eight patients with associated paraproteinemia.
Topics: Animals; Blood Protein Disorders; Buffers; Chromatography, DEAE-Cellulose; Cryoglobulins; Electropho | 1973 |
Dissociation, reaggregation, and subunit structure studies of some human gamma-M-globulins.
Topics: Amides; Amino Acids; Azirines; Blood Protein Electrophoresis; gamma-Globulins; Guanidines; Humans; I | 1967 |
Inhibitory effects of monoclonal immunoglobulins on anti-globulin reaction.
Topics: Amino Acids; Antibodies, Anti-Idiotypic; Bence Jones Protein; Carbohydrates; Chromatography; Coombs | 1968 |
Structural analysis of a slowly sedimenting proteolytic fragment of human immunoglobulin M.
Topics: Amino Acids; Chromatography, Gel; gamma-Globulins; Immune Sera; Immunodiffusion; Immunoelectrophores | 1969 |
Recombination of the polypeptide chains of a Waldenström's IgM that binds IgG.
Topics: Antigen-Antibody Reactions; Centrifugation, Density Gradient; Disulfides; Dithiothreitol; Electropho | 1973 |
7S immunoglobulin M (IgM) from serum purified by anti-mu-chain immunoadsorbent: comparison of the reassociation properties of 7S IgM and various 19S IgM subunits.
Topics: Adsorption; Centrifugation, Density Gradient; Chromatography, Gel; Electrophoresis, Polyacrylamide G | 1973 |
B and T lymphocyte subpopulations in human peripheral blood.
Topics: Adult; Animals; B-Lymphocytes; Binding Sites; Cattle; Cell Separation; Complement System Proteins; E | 1974 |
Characterization of subunits from a reconstituted monoclonal IgM that binds IgG.
Topics: Acetamides; Animals; Dithiothreitol; Erythrocytes; Hemagglutination Tests; Humans; Immunoelectrophor | 1974 |
Formation of hybrid IgM subunits.
Topics: Alkylation; Animals; Antibodies, Heterophile; Antibody Specificity; Autoradiography; Centrifugation, | 1972 |
[On the conformaton of macroglobulins. II. Acid dissociation and mercaptoethanol denaturation].
Topics: Chemical Phenomena; Chemistry; Humans; In Vitro Techniques; Macroglobulins; Mercaptoethanol; RNA; Wa | 1965 |
[On the conformation of macroglobulins in Waldenstöm's disease. 3. On the kinetics of mercaptoethanol denaturation].
Topics: Blood Protein Electrophoresis; Blood Sedimentation; Blood Viscosity; Humans; Hydrogen-Ion Concentrat | 1967 |
Antigenic heterogeneity of reduced and alkylated subunits of human monoclonal macroglobulins.
Topics: Alkylation; Amides; Antigens; Blood Protein Electrophoresis; Freund's Adjuvant; Humans; Immune Sera; | 1968 |
Studies on the reduction of a human 19S immunoglobulin M.
Topics: Alkylation; Animals; Antigens; Bence Jones Protein; Carbohydrates; Carbon Isotopes; Chemical Phenome | 1969 |
Differentiation of human IgM subclasses by the ability to interact with a factor resembling the first component of complement.
Topics: Animals; Bence Jones Protein; Binding Sites; Chromatography, Gel; Complement System Proteins; Electr | 1969 |
Inhibition of complement-mediated hemolysis by rheumatoid arthritis sera studies in agarose gel.
Topics: Agar; Animals; Antibodies; Arthritis, Rheumatoid; Cellulose; Chromatography; Complement System Prote | 1970 |
A macroglobulin with inhibitory activity against coagulation factor VIII.
Topics: Adsorption; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Transfusion; Chlorambucil; C | 1970 |
Inhibition of natural cytotoxic rabbit antibody by human IgM: production of nontoxic rabbit serum for use as complement source.
Topics: Animals; Antigen-Antibody Reactions; Burkitt Lymphoma; Cell Line; Chromatography; Chromatography, Ge | 1970 |
Reactions of G-myeloma sera with rheumatoid arthritis sera.
Topics: Animals; Arthritis, Rheumatoid; Complement Inactivator Proteins; Erythrocytes; Guinea Pigs; Hemagglu | 1970 |
Dissociation of a small proportion of a human IgM population into Fcmu, Fcmu, and free light chains following reduction.
Topics: Absorption; Antigen-Antibody Reactions; Chromatography, Gel; Humans; Immune Sera; Immunochemistry; I | 1970 |
[Immunochemical study of 3 cases of pyroglobulinemia].
Topics: Amides; Blood Protein Disorders; Blood Protein Electrophoresis; Blood Proteins; Hot Temperature; Hum | 1970 |
Low molecular weight IgM-immunoglobulins in Waldenström's macroglobulinemia.
Topics: Acrylates; Chromatography, Gel; Humans; Immune Sera; Immunodiffusion; Immunoglobulin G; Immunoglobul | 1970 |
Electrophoretic and immunologic differences between monoclonal IgM molecules and their subunits in native plasma.
Topics: Animals; Antigen-Antibody Reactions; Humans; Immunodiffusion; Immunoelectrophoresis; Immunoglobulin | 1970 |
Isoantibodies to human IgM: serologic and immunochemical investigations.
Topics: Antibodies, Anti-Idiotypic; Antibody Specificity; Antigens; Asian People; Bence Jones Protein; Black | 1971 |
Dissociation of Waldenström's immunoglobulin M by the disulfide interchange reaction.
Topics: Alkylation; Buffers; Chemical Phenomena; Chemistry; Chromatography, Gel; Cystamine; Humans; Hydrogen | 1971 |
Spontaneous reoxidation of the subunits of immunoglobulin M (IgM).
Topics: Alkylation; Humans; Immunochemistry; Immunoglobulin M; Immunoglobulins; Mercaptoethanol; Mercaptoeth | 1971 |
Degradation of human IgM by pepsin: characterization of a high molecular weight fragment.
Topics: Alkylation; Animals; Autoanalysis; Chromatography, Gel; Diffusion; Electrophoresis, Disc; Goats; Hum | 1971 |
IgM lymphocytotoxic antibodies following multiple transfusion.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Anemia, Sickle Cell; Antibodies; Antibodies, Anti-Idiotyp | 1971 |
Biological and physical properties of a human m-cryoglobulin and its monomer subunit.
Topics: Alkylation; Binding Sites; Blood Proteins; Carbohydrates; Chemical Precipitation; Complement Fixatio | 1971 |
Reversible dissociation of reduced subunits of human M-globulins ino 5 S component.
Topics: Alkylation; Chromatography, Gel; Disulfides; Humans; Hydrogen-Ion Concentration; Immunodiffusion; Im | 1971 |