mercaptoethanol has been researched along with Soft Tissue Neoplasms in 7 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
Soft Tissue Neoplasms: Neoplasms of whatever cell type or origin, occurring in the extraskeletal connective tissue framework of the body including the organs of locomotion and their various component structures, such as nerves, blood vessels, lymphatics, etc.
| Excerpt | Relevance | Reference |
|---|---|---|
| "European and American investigators have reported response rates of 38% to 83% for ifosfamide alone in pretreated sarcomas." | 9.06 | Response to ifosfamide and mesna: 124 previously treated patients with metastatic or unresectable sarcoma. ( Antman, KH; Elias, A; Grier, HE; Ryan, L; Sherman, D, 1989) |
| "In a phase II study, 42 patients with advanced soft-tissue sarcoma were treated with ifosfamide by 24-h infusion and mesna by 4-h IV bolus, repeated every 3 weeks." | 7.66 | High-dose alkylation therapy using ifosfamide infusion with mesna in the treatment of adult advanced soft-tissue sarcoma. ( Gowing, NF; Harper, PG; Kaye, SB; Mooney, CA; Parsons, CA; Stuart-Harris, RC; Wiltshaw, E, 1983) |
| "European and American investigators have reported response rates of 38% to 83% for ifosfamide alone in pretreated sarcomas." | 5.06 | Response to ifosfamide and mesna: 124 previously treated patients with metastatic or unresectable sarcoma. ( Antman, KH; Elias, A; Grier, HE; Ryan, L; Sherman, D, 1989) |
| "In a phase II study, 42 patients with advanced soft-tissue sarcoma were treated with ifosfamide by 24-h infusion and mesna by 4-h IV bolus, repeated every 3 weeks." | 3.66 | High-dose alkylation therapy using ifosfamide infusion with mesna in the treatment of adult advanced soft-tissue sarcoma. ( Gowing, NF; Harper, PG; Kaye, SB; Mooney, CA; Parsons, CA; Stuart-Harris, RC; Wiltshaw, E, 1983) |
| "Ifosfamide and mesna were administered to 77 patients with advanced malignancies." | 1.27 | Prediction of ifosfamide/mesna associated encephalopathy. ( Blackledge, G; Blake, AE; Honigsberger, L; Kelly, KA; Meanwell, CA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stuart-Harris, R | 1 |
| Harper, PG | 2 |
| Kaye, SB | 2 |
| Wiltshaw, E | 2 |
| Stuart-Harris, RC | 1 |
| Parsons, CA | 1 |
| Mooney, CA | 1 |
| Gowing, NF | 1 |
| Antman, KH | 1 |
| Ryan, L | 1 |
| Elias, A | 1 |
| Sherman, D | 1 |
| Grier, HE | 1 |
| Willemse, PH | 1 |
| de Vries, EG | 1 |
| Meanwell, CA | 1 |
| Blake, AE | 1 |
| Kelly, KA | 1 |
| Honigsberger, L | 1 |
| Blackledge, G | 1 |
| Klein, HO | 1 |
| Dias Wickramanayake, P | 1 |
| Coerper, C | 1 |
| Christian, E | 1 |
| Cantwell, BM | 1 |
| Carmichael, J | 1 |
| Ghani, S | 1 |
| Harris, AL | 1 |
1 trial available for mercaptoethanol and Soft Tissue Neoplasms
| Article | Year |
|---|---|
Response to ifosfamide and mesna: 124 previously treated patients with metastatic or unresectable sarcoma.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Female; Hematuria; Human | 1989 |
6 other studies available for mercaptoethanol and Soft Tissue Neoplasms
| Article | Year |
|---|---|
High-dose ifosfamide by infusion with mesna in advanced soft tissue sarcoma.
Topics: Adolescent; Adult; Aged; Cyclophosphamide; Female; Humans; Ifosfamide; Male; Mercaptoethanol; Mesna; | 1983 |
High-dose alkylation therapy using ifosfamide infusion with mesna in the treatment of adult advanced soft-tissue sarcoma.
Topics: Adolescent; Adult; Aged; Cyclophosphamide; Drug Evaluation; Drug Therapy, Combination; Female; Human | 1983 |
Mesna: continuous or bolus infusion?
Topics: Drug Administration Schedule; Humans; Ifosfamide; Infusions, Intravenous; Injections, Intravenous; M | 1989 |
Prediction of ifosfamide/mesna associated encephalopathy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Electroencephalography; Female; Huma | 1986 |
Treatment of advanced soft tissue and osteogenic sarcomas with continuous infusion of ifosfamide and mesna.
Topics: Female; Humans; Ifosfamide; Infusions, Intravenous; Male; Mercaptoethanol; Mesna; Middle Aged; Osteo | 1986 |
A phase II study of ifosfamide/mesna with doxorubicin for adult soft tissue sarcoma.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain; Doxorubicin; Drug Ev | 1988 |