mercaptoethanol has been researched along with Rhabdomyosarcoma in 5 studies
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.
Rhabdomyosarcoma: A malignant solid tumor arising from mesenchymal tissues which normally differentiate to form striated muscle. It can occur in a wide variety of sites. It is divided into four distinct types: pleomorphic, predominantly in male adults; alveolar (RHABDOMYOSARCOMA, ALVEOLAR), mainly in adolescents and young adults; embryonal (RHABDOMYOSARCOMA, EMBRYONAL), predominantly in infants and children; and botryoidal, also in young children. It is one of the most frequently occurring soft tissue sarcomas and the most common in children under 15. (From Dorland, 27th ed; Holland et al., Cancer Medicine, 3d ed, p2186; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, pp1647-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mesna is a sulfhydryl compound that reacts with the metabolites of cyclophosphamide that are excreted in the urine and may produce bladder wall irritation." | 5.27 | Efficacy of mesna in preventing further cyclophosphamide-induced hemorrhagic cystitis. ( Luce, JK; Simons, JA, 1988) |
| "Mesna is a sulfhydryl compound that reacts with the metabolites of cyclophosphamide that are excreted in the urine and may produce bladder wall irritation." | 1.27 | Efficacy of mesna in preventing further cyclophosphamide-induced hemorrhagic cystitis. ( Luce, JK; Simons, JA, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rand, K | 1 |
| Davis, J | 1 |
| Gilden, RV | 1 |
| Oroszlan, S | 1 |
| Long, C | 1 |
| Iwasaku-Fujimoto, M | 1 |
| Fujiwara, F | 1 |
| Todo, S | 1 |
| Morioka, Y | 1 |
| Imashuku, S | 1 |
| Verdeguer, A | 1 |
| Castel, V | 1 |
| Esquembre, C | 1 |
| Ferris, J | 1 |
| Fernandez, JM | 1 |
| Ruiz, JG | 1 |
| Salloum, E | 1 |
| Flamant, F | 1 |
| Ghosn, M | 1 |
| Taleb, N | 1 |
| Akatchereian, C | 1 |
| Luce, JK | 1 |
| Simons, JA | 1 |
5 other studies available for mercaptoethanol and Rhabdomyosarcoma
| Article | Year |
|---|---|
Fusion inhibition: bioassay of type C viral protein.
Topics: Cell Fusion; Cell Line; Glioma; Hot Temperature; Mercaptoethanol; Molecular Weight; Neutralization T | 1975 |
[Effects of mesna (2-mercaptoethane sodium sulfonate) in children with malignant disease receiving oxazaphosphorine chemotherapy].
Topics: Bone Neoplasms; Child; Cyclophosphamide; Cystitis; Female; Hematuria; Humans; Ifosfamide; Leukemia; | 1990 |
Fatal encephalopathy with ifosfamide/mesna.
Topics: Brain Diseases; Child; Drug Therapy, Combination; Humans; Ifosfamide; Male; Mercaptoethanol; Mesna; | 1989 |
Irreversible encephalopathy with ifosfamide/mesna.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Diseases; Child, Preschool; Dactinomycin; Fema | 1987 |
Efficacy of mesna in preventing further cyclophosphamide-induced hemorrhagic cystitis.
Topics: Adolescent; Adult; Child; Cyclophosphamide; Cystitis; Cystoscopy; Female; Hematuria; Humans; Male; M | 1988 |